Roles of signaling and transcriptional networks in pathological lymphangiogenesis.
(2016) In Advanced Drug Delivery Reviews 99. p.161-171- Abstract
- Lymphangiogenesis, the generation of new lymphatic vessels, plays important roles in cancer metastasis. Outstanding progress during the past decade has dramatically increased the novel knowledge and insights of the mechanisms underlying the generation of new lymphatic vessels, the roles of transcription factors and lymphangiogenic growth factors during physiological development and pathological processes such as cancer and inflammation. Furthermore, an understanding of the molecular consequences during tumor lymphangiogenesis has provided chances to develop better diagnostic and therapeutic approaches that aim to limit the progression of cancer. In this article, we will explain the current knowledge of how lymphatic function is altered in... (More)
- Lymphangiogenesis, the generation of new lymphatic vessels, plays important roles in cancer metastasis. Outstanding progress during the past decade has dramatically increased the novel knowledge and insights of the mechanisms underlying the generation of new lymphatic vessels, the roles of transcription factors and lymphangiogenic growth factors during physiological development and pathological processes such as cancer and inflammation. Furthermore, an understanding of the molecular consequences during tumor lymphangiogenesis has provided chances to develop better diagnostic and therapeutic approaches that aim to limit the progression of cancer. In this article, we will explain the current knowledge of how lymphatic function is altered in various pathological conditions including cancer progression. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8829159
- author
- Yoshimatsu, Yasuhiro ; Miyazaki, Hideki LU and Watabe, Tetsuro
- organization
- publishing date
- 2016-02-03
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Advanced Drug Delivery Reviews
- volume
- 99
- pages
- 161 - 171
- publisher
- Elsevier
- external identifiers
-
- pmid:26850127
- scopus:84962615544
- pmid:26850127
- wos:000374421500004
- ISSN
- 0169-409X
- DOI
- 10.1016/j.addr.2016.01.020
- language
- English
- LU publication?
- yes
- id
- 2e34ea38-09c6-480e-a6a8-71c7b43da354 (old id 8829159)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26850127?dopt=Abstract
- date added to LUP
- 2016-04-04 08:56:36
- date last changed
- 2022-04-08 01:06:20
@article{2e34ea38-09c6-480e-a6a8-71c7b43da354,
abstract = {{Lymphangiogenesis, the generation of new lymphatic vessels, plays important roles in cancer metastasis. Outstanding progress during the past decade has dramatically increased the novel knowledge and insights of the mechanisms underlying the generation of new lymphatic vessels, the roles of transcription factors and lymphangiogenic growth factors during physiological development and pathological processes such as cancer and inflammation. Furthermore, an understanding of the molecular consequences during tumor lymphangiogenesis has provided chances to develop better diagnostic and therapeutic approaches that aim to limit the progression of cancer. In this article, we will explain the current knowledge of how lymphatic function is altered in various pathological conditions including cancer progression.}},
author = {{Yoshimatsu, Yasuhiro and Miyazaki, Hideki and Watabe, Tetsuro}},
issn = {{0169-409X}},
language = {{eng}},
month = {{02}},
pages = {{161--171}},
publisher = {{Elsevier}},
series = {{Advanced Drug Delivery Reviews}},
title = {{Roles of signaling and transcriptional networks in pathological lymphangiogenesis.}},
url = {{http://dx.doi.org/10.1016/j.addr.2016.01.020}},
doi = {{10.1016/j.addr.2016.01.020}},
volume = {{99}},
year = {{2016}},
}