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Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin

Odenholt, Inga LU ; Lowdin, E and Cars, O (2003) In Antimicrobial Agents and Chemotherapy 47(10). p.3352-3356
Abstract
Postantibiotic effects (PAEs), postantibiotic sub-MIC effects, and sub-MIC effects of the new nonfluoroquinolone PGE-9509924, ciprofloxacin, and levofloxacin against gram-positive and gram-negative strains were investigated. In comparison to ciprofloxacin and levofloxacin, PGE-9509924 exerted very similar PAEs against all strains except for both strains of Streptococcus pneumoniae, where longer PAEs were found for PGE-9509924. All three investigated quinolones showed no minimal PAEs against Pseudomonas aeruginosa.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Antimicrobial Agents and Chemotherapy
volume
47
issue
10
pages
3352 - 3356
publisher
American Society for Microbiology
external identifiers
  • pmid:14506057
  • wos:000185612600053
  • scopus:0141924815
ISSN
1098-6596
DOI
10.1128/AAC.47.10.3352-3356.2003
language
English
LU publication?
yes
id
fcb5dfe2-e9ac-48d6-947a-11ac17098721 (old id 899924)
alternative location
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=201171
date added to LUP
2016-04-01 16:06:55
date last changed
2022-04-15 02:11:11
@article{fcb5dfe2-e9ac-48d6-947a-11ac17098721,
  abstract     = {{Postantibiotic effects (PAEs), postantibiotic sub-MIC effects, and sub-MIC effects of the new nonfluoroquinolone PGE-9509924, ciprofloxacin, and levofloxacin against gram-positive and gram-negative strains were investigated. In comparison to ciprofloxacin and levofloxacin, PGE-9509924 exerted very similar PAEs against all strains except for both strains of Streptococcus pneumoniae, where longer PAEs were found for PGE-9509924. All three investigated quinolones showed no minimal PAEs against Pseudomonas aeruginosa.}},
  author       = {{Odenholt, Inga and Lowdin, E and Cars, O}},
  issn         = {{1098-6596}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{3352--3356}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Antimicrobial Agents and Chemotherapy}},
  title        = {{Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin}},
  url          = {{http://dx.doi.org/10.1128/AAC.47.10.3352-3356.2003}},
  doi          = {{10.1128/AAC.47.10.3352-3356.2003}},
  volume       = {{47}},
  year         = {{2003}},
}