Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features
Nyberg, Lisa LU ; Björk, Jan ; Björkdahl, Peter LU ; Ekberg, Olle LU ; Sjöberg, Klas LU
and Vigren, Lina
LU
(2017)
In BMC Gastroenterology
17(1).
- Abstract
Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate... (More)
Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM. Conclusions: We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.
(Less)
- author
- Nyberg, Lisa
LU
; Björk, Jan
; Björkdahl, Peter
LU
; Ekberg, Olle
LU
; Sjöberg, Klas
LU
and Vigren, Lina
LU
- organization
- publishing date
- 2017-06-13
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Clinical classification, Mesenteric panniculitis, Mesenteritis, Panniculitis, Radiological classification, Retractile mesenteritis, Sclerosing mesenteritis
- in
- BMC Gastroenterology
- volume
- 17
- issue
- 1
- article number
- 75
- publisher
- BioMed Central (BMC)
- external identifiers
-
- scopus:85020676301
- wos:000403642500001
- pmid:28610559
- ISSN
- 1471-230X
- DOI
- 10.1186/s12876-017-0632-7
- language
- English
- LU publication?
- yes
- id
- 98f3bd8e-7d5f-4450-aa94-c81643ca303d
- date added to LUP
- 2017-08-11 15:28:41
- date last changed
- 2024-02-29 19:43:20
@article{98f3bd8e-7d5f-4450-aa94-c81643ca303d,
abstract = {{<p>Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Methods: Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study. Results: Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM. Conclusions: We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.</p>}},
author = {{Nyberg, Lisa and Björk, Jan and Björkdahl, Peter and Ekberg, Olle and Sjöberg, Klas and Vigren, Lina}},
issn = {{1471-230X}},
keywords = {{Clinical classification; Mesenteric panniculitis; Mesenteritis; Panniculitis; Radiological classification; Retractile mesenteritis; Sclerosing mesenteritis}},
language = {{eng}},
month = {{06}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Gastroenterology}},
title = {{Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features}},
url = {{http://dx.doi.org/10.1186/s12876-017-0632-7}},
doi = {{10.1186/s12876-017-0632-7}},
volume = {{17}},
year = {{2017}},
}