Cachexia: a problem of energetic inefficiency
(2014) In Journal of Cachexia, Sarcopenia and Muscle 5(4). p.86-279- Abstract
An alteration of energy balance is the immediate cause of the so-called cachexia. Although alterations of energy intake are often associated with cachexia, it has lately became clear that an increased energy expenditure is the main cause of wasting associated with different types of pathological conditions, such as cancer, infections or chronic heart failure among others. Different types of molecular mechanisms contribute to energy expenditure and, therefore, involuntary body weight loss; among them, adenosine triphosphate (ATP) consumption by sarcoplasmic reticulum Ca(2+) pumps could represent a key mechanism. In other cases, an increase in energy inefficiency will further contribute to energy imbalance.
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https://lup.lub.lu.se/record/a04a80a1-8def-44ee-a3b5-7d46ac6520f6
- author
- Argilés, Josep M ; Fontes-Oliveira, Cibely Cristine LU ; Toledo, Miriam ; López-Soriano, Francisco J and Busquets, Sílvia
- publishing date
- 2014-12
- type
- Contribution to journal
- publication status
- published
- keywords
- Journal Article
- in
- Journal of Cachexia, Sarcopenia and Muscle
- volume
- 5
- issue
- 4
- pages
- 86 - 279
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:25118829
- scopus:84951560724
- ISSN
- 2190-5991
- DOI
- 10.1007/s13539-014-0154-x
- language
- English
- LU publication?
- no
- id
- a04a80a1-8def-44ee-a3b5-7d46ac6520f6
- date added to LUP
- 2017-02-28 16:09:39
- date last changed
- 2024-04-14 06:44:02
@article{a04a80a1-8def-44ee-a3b5-7d46ac6520f6,
abstract = {{<p>An alteration of energy balance is the immediate cause of the so-called cachexia. Although alterations of energy intake are often associated with cachexia, it has lately became clear that an increased energy expenditure is the main cause of wasting associated with different types of pathological conditions, such as cancer, infections or chronic heart failure among others. Different types of molecular mechanisms contribute to energy expenditure and, therefore, involuntary body weight loss; among them, adenosine triphosphate (ATP) consumption by sarcoplasmic reticulum Ca(2+) pumps could represent a key mechanism. In other cases, an increase in energy inefficiency will further contribute to energy imbalance.</p>}},
author = {{Argilés, Josep M and Fontes-Oliveira, Cibely Cristine and Toledo, Miriam and López-Soriano, Francisco J and Busquets, Sílvia}},
issn = {{2190-5991}},
keywords = {{Journal Article}},
language = {{eng}},
number = {{4}},
pages = {{86--279}},
publisher = {{Wiley-Blackwell}},
series = {{Journal of Cachexia, Sarcopenia and Muscle}},
title = {{Cachexia: a problem of energetic inefficiency}},
url = {{http://dx.doi.org/10.1007/s13539-014-0154-x}},
doi = {{10.1007/s13539-014-0154-x}},
volume = {{5}},
year = {{2014}},
}