REDOX regulation of mitochondrial function in plants
(2012) In Plant, Cell and Environment 35(2). p.80-271- Abstract
Mitochondrial components dynamically change in response to environmental and developmental cues. However, the regulatory pathways that underlie these changes are largely unknown. A global analysis of changes in mitochondrial components at the transcript, protein and metabolite levels was undertaken, to gain a greater insight into how mitochondrial functions are regulated and respond to various internal or external cues. At the transcript level, large-scale changes in groups of genes suggest the presence of co-regulatory mechanisms for these components. Furthermore, the pathways that regulate these changes appear to be integrated into regulatory pathways that alter a variety of functions in cells. However, the changes in transcripts are... (More)
Mitochondrial components dynamically change in response to environmental and developmental cues. However, the regulatory pathways that underlie these changes are largely unknown. A global analysis of changes in mitochondrial components at the transcript, protein and metabolite levels was undertaken, to gain a greater insight into how mitochondrial functions are regulated and respond to various internal or external cues. At the transcript level, large-scale changes in groups of genes suggest the presence of co-regulatory mechanisms for these components. Furthermore, the pathways that regulate these changes appear to be integrated into regulatory pathways that alter a variety of functions in cells. However, the changes in transcripts are not always observed at the protein or the metabolite level. This is likely to be due to post-transcriptional levels of regulation and also the fact that in-depth profiles, which have been obtained for transcripts from a variety of studies, are currently not available for proteins and metabolites. Thus, while transcripts for genes give us a picture of what the cells are 'thinking' in relation to mitochondrial components, some of these responses may be lost in translation.
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- author
- Giraud, Estelle ; Van Aken, Olivier LU ; Uggalla, Vindya and Whelan, James
- publishing date
- 2012-02
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Gene Expression Regulation, Plant, Metabolomics, Mitochondria, Oxidation-Reduction, Oxidative Stress, Plants, Proteomics, Stress, Physiological, Transcriptome
- in
- Plant, Cell and Environment
- volume
- 35
- issue
- 2
- pages
- 10 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:21332513
- scopus:84855348301
- ISSN
- 0140-7791
- DOI
- 10.1111/j.1365-3040.2011.02293.x
- language
- English
- LU publication?
- no
- id
- b9569dbd-b25f-455a-b91f-bfb237742acb
- date added to LUP
- 2017-05-09 10:07:19
- date last changed
- 2024-04-14 10:13:26
@article{b9569dbd-b25f-455a-b91f-bfb237742acb,
abstract = {{<p>Mitochondrial components dynamically change in response to environmental and developmental cues. However, the regulatory pathways that underlie these changes are largely unknown. A global analysis of changes in mitochondrial components at the transcript, protein and metabolite levels was undertaken, to gain a greater insight into how mitochondrial functions are regulated and respond to various internal or external cues. At the transcript level, large-scale changes in groups of genes suggest the presence of co-regulatory mechanisms for these components. Furthermore, the pathways that regulate these changes appear to be integrated into regulatory pathways that alter a variety of functions in cells. However, the changes in transcripts are not always observed at the protein or the metabolite level. This is likely to be due to post-transcriptional levels of regulation and also the fact that in-depth profiles, which have been obtained for transcripts from a variety of studies, are currently not available for proteins and metabolites. Thus, while transcripts for genes give us a picture of what the cells are 'thinking' in relation to mitochondrial components, some of these responses may be lost in translation.</p>}},
author = {{Giraud, Estelle and Van Aken, Olivier and Uggalla, Vindya and Whelan, James}},
issn = {{0140-7791}},
keywords = {{Gene Expression Regulation, Plant; Metabolomics; Mitochondria; Oxidation-Reduction; Oxidative Stress; Plants; Proteomics; Stress, Physiological; Transcriptome}},
language = {{eng}},
number = {{2}},
pages = {{80--271}},
publisher = {{Wiley-Blackwell}},
series = {{Plant, Cell and Environment}},
title = {{REDOX regulation of mitochondrial function in plants}},
url = {{http://dx.doi.org/10.1111/j.1365-3040.2011.02293.x}},
doi = {{10.1111/j.1365-3040.2011.02293.x}},
volume = {{35}},
year = {{2012}},
}