Características antigénicas de los virus aislados del líquido cefalorraquídeo de pacientes con neuropatía epidémica
(1998) In Revista cubana de medicina tropical 50 Suppl. p.4-231- Abstract
During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism... (More)
During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism through which these viruses take part in the etiopathogenesis of epidemic neuropathy in Cuba.
(Less)
- author
- Sarmiento Pérez, L ; Más Lago, P ; Avalos Redón, I ; Bello Corredor, M and Palomera Puentes, R
- alternative title
- The antigenic characteristics of the viruses isolated from the cerebrospinal fluid of patients with epidemic neuropathy
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Antigens, Viral/analysis, Blotting, Western, Cerebrospinal Fluid/virology, Cuba/epidemiology, Disease Outbreaks, Enterovirus/immunology, Humans, Peripheral Nervous System Diseases/epidemiology
- in
- Revista cubana de medicina tropical
- volume
- 50 Suppl
- pages
- 4 pages
- publisher
- Editorial Ciencias Medicas
- external identifiers
-
- pmid:10349452
- scopus:0032249289
- ISSN
- 0375-0760
- language
- Spanish
- LU publication?
- no
- id
- b9e95735-ae5a-4845-9f2b-90d0633eff85
- alternative location
- http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601998000400002
- date added to LUP
- 2019-07-08 15:17:46
- date last changed
- 2024-01-01 15:46:21
@article{b9e95735-ae5a-4845-9f2b-90d0633eff85,
abstract = {{<p>During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism through which these viruses take part in the etiopathogenesis of epidemic neuropathy in Cuba.</p>}},
author = {{Sarmiento Pérez, L and Más Lago, P and Avalos Redón, I and Bello Corredor, M and Palomera Puentes, R}},
issn = {{0375-0760}},
keywords = {{Antigens, Viral/analysis; Blotting, Western; Cerebrospinal Fluid/virology; Cuba/epidemiology; Disease Outbreaks; Enterovirus/immunology; Humans; Peripheral Nervous System Diseases/epidemiology}},
language = {{spa}},
pages = {{4--231}},
publisher = {{Editorial Ciencias Medicas}},
series = {{Revista cubana de medicina tropical}},
title = {{Características antigénicas de los virus aislados del líquido cefalorraquídeo de pacientes con neuropatía epidémica}},
url = {{http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601998000400002}},
volume = {{50 Suppl}},
year = {{1998}},
}