Non-adherence to immunosuppressants after lung transplantation- a common risk behavior
(2019) In Open Nursing Journal- Abstract
Background:
After lung transplantation, life-long treatment with immunosuppressive medication is required to prevent rejection and graft loss but adherence to immunosuppressive treatment may be difficult for the lung recipient. Adherence is essential and non-adherence to immunosuppressive treatment can lead to graft loss and death.
Objective:
The aim of this cross-sectional study was to investigate the prevalence of non-adherence 1 to 5 years after lung transplantation in relation to symptom burden, health literacy, psychological well-being and relevant demographic variables.
Methods:
117 adult lung recipients, due for their annual follow-up 1-5 years after lung transplantation, participated. Four... (More)
Background:
After lung transplantation, life-long treatment with immunosuppressive medication is required to prevent rejection and graft loss but adherence to immunosuppressive treatment may be difficult for the lung recipient. Adherence is essential and non-adherence to immunosuppressive treatment can lead to graft loss and death.
Objective:
The aim of this cross-sectional study was to investigate the prevalence of non-adherence 1 to 5 years after lung transplantation in relation to symptom burden, health literacy, psychological well-being and relevant demographic variables.
Methods:
117 adult lung recipients, due for their annual follow-up 1-5 years after lung transplantation, participated. Four self-report instruments were used for assessment: the Basel Assessment of Adherence with Immunosuppressive Medication Scale, the Newest Vital Sign, the Psychological General Well-Being and the Organ Transplant Symptom and Wellbeing Instrument. Statistical analysis was performed.
Results:
Thirty percent of the lung recipients were non-adherent. The most common non-adherence dimension was not taking a dose (43%) and not being punctual with the regimen (80%). Of those working full time or part time, 43% were non-adherent (p=.032). A higher level of non-adherence was reported a long time after LuTx with the highest level at the 3-year follow-up.
Conclusion:
The level of non-adherence among lung recipients was high. The highest levels were found among those who had returned to work. Non-adherence increased with time after lung transplantation.
(Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d6c7521e-2aa1-4007-b582-b8ad14c3293e
- author
- Lennerling, Annette ; Kisch, Annika LU and Forsberg, Anna LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Open Nursing Journal
- issue
- 58
- publisher
- Bentham Science Publishers
- external identifiers
-
- scopus:85067106886
- ISSN
- 1874-4346
- DOI
- 10.2174/1874434601913010108
- language
- English
- LU publication?
- yes
- id
- d6c7521e-2aa1-4007-b582-b8ad14c3293e
- date added to LUP
- 2019-05-30 22:23:55
- date last changed
- 2022-04-26 00:52:57
@article{d6c7521e-2aa1-4007-b582-b8ad14c3293e,
abstract = {{<br/>Background:<br/><br/>After lung transplantation, life-long treatment with immunosuppressive medication is required to prevent rejection and graft loss but adherence to immunosuppressive treatment may be difficult for the lung recipient. Adherence is essential and non-adherence to immunosuppressive treatment can lead to graft loss and death.<br/>Objective:<br/><br/>The aim of this cross-sectional study was to investigate the prevalence of non-adherence 1 to 5 years after lung transplantation in relation to symptom burden, health literacy, psychological well-being and relevant demographic variables.<br/>Methods:<br/><br/>117 adult lung recipients, due for their annual follow-up 1-5 years after lung transplantation, participated. Four self-report instruments were used for assessment: the Basel Assessment of Adherence with Immunosuppressive Medication Scale, the Newest Vital Sign, the Psychological General Well-Being and the Organ Transplant Symptom and Wellbeing Instrument. Statistical analysis was performed.<br/>Results:<br/><br/>Thirty percent of the lung recipients were non-adherent. The most common non-adherence dimension was not taking a dose (43%) and not being punctual with the regimen (80%). Of those working full time or part time, 43% were non-adherent (p=.032). A higher level of non-adherence was reported a long time after LuTx with the highest level at the 3-year follow-up.<br/>Conclusion:<br/><br/>The level of non-adherence among lung recipients was high. The highest levels were found among those who had returned to work. Non-adherence increased with time after lung transplantation.<br/>}},
author = {{Lennerling, Annette and Kisch, Annika and Forsberg, Anna}},
issn = {{1874-4346}},
language = {{eng}},
number = {{58}},
publisher = {{Bentham Science Publishers}},
series = {{Open Nursing Journal}},
title = {{Non-adherence to immunosuppressants after lung transplantation- a common risk behavior}},
url = {{http://dx.doi.org/10.2174/1874434601913010108}},
doi = {{10.2174/1874434601913010108}},
year = {{2019}},
}