Characterization of genetic variation in TLR8 in relation to allergic rhinitis.
Henmyr, V; Lind-Halldén, C; Carlberg, D; Halldén, C, et al. (2015-12-02). Characterization of genetic variation in TLR8 in relation to allergic rhinitis.. Allergy
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Published
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English
Authors:
Henmyr, V
;
Lind-Halldén, C
;
Carlberg, D
;
Halldén, C
, et al.
Department:
Molecular Cell Biology
Abstract:
A previous investigation of all 10 TLR-genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. The present study therefore searches for rare variants in the TLR8 region and also investigates the reproducibility of previous SNP associations.
Keywords:
Respiratory Medicine and Allergy ;
Medical Genetics
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