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Predictors for Outcome after Vacuum Assisted Closure Therapy of Peri-vascular Surgical Site Infections in the Groin.

Svensson, S; Monsen, C; Kölbel, Tilo LU and Acosta, Stefan (2008) In European journal of vascular and endovascular surgery 36. p.84-89
Abstract
OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC((R))) therapy of peri-vascular surgical site infections in the groin after arterial surgery. DESIGN: Retrospective study. MATERIALS: Thirty-three groins received VAC((R)) therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital. METHODS: Following surgical revision, VAC((R)) therapy was applied in the groin at a continuous topical negative pressure of 125mmHg. The median follow up time was 16 months. RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC((R)) therapy was... (More)
OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC((R))) therapy of peri-vascular surgical site infections in the groin after arterial surgery. DESIGN: Retrospective study. MATERIALS: Thirty-three groins received VAC((R)) therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital. METHODS: Following surgical revision, VAC((R)) therapy was applied in the groin at a continuous topical negative pressure of 125mmHg. The median follow up time was 16 months. RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC((R)) therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC((R)) associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC((R)) treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001). CONCLUSIONS: VAC((R)) treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC((R)) therapy were associated with amputation and death. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European journal of vascular and endovascular surgery
volume
36
pages
84 - 89
publisher
Elsevier
external identifiers
  • PMID:18294875
  • WOS:000257856300016
  • Scopus:45749086056
ISSN
1532-2165
DOI
10.1016/j.ejvs.2007.12.020
language
English
LU publication?
yes
id
31c699ab-8f0f-46ea-a15c-428f0f75bd20 (old id 1041580)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18294875?dopt=Abstract
date added to LUP
2008-03-06 15:41:13
date last changed
2016-11-06 04:25:09
@misc{31c699ab-8f0f-46ea-a15c-428f0f75bd20,
  abstract     = {OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC((R))) therapy of peri-vascular surgical site infections in the groin after arterial surgery. DESIGN: Retrospective study. MATERIALS: Thirty-three groins received VAC((R)) therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital. METHODS: Following surgical revision, VAC((R)) therapy was applied in the groin at a continuous topical negative pressure of 125mmHg. The median follow up time was 16 months. RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC((R)) therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC((R)) associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC((R)) treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p&lt;0.001). CONCLUSIONS: VAC((R)) treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC((R)) therapy were associated with amputation and death.},
  author       = {Svensson, S and Monsen, C and Kölbel, Tilo and Acosta, Stefan},
  issn         = {1532-2165},
  language     = {eng},
  pages        = {84--89},
  publisher    = {ARRAY(0xaab24e8)},
  series       = {European journal of vascular and endovascular surgery },
  title        = {Predictors for Outcome after Vacuum Assisted Closure Therapy of Peri-vascular Surgical Site Infections in the Groin.},
  url          = {http://dx.doi.org/10.1016/j.ejvs.2007.12.020},
  volume       = {36},
  year         = {2008},
}