Steady-State Diffusion in Complex Amphiphilic Films
(2009)- Abstract
- The relation between structure and diffusive transport at steady-state
is investigated theoretically for amphiphilic systems. Amphiphilic
systems typically show a large response to moderate changes in control
parameters, such as temperature, osmotic pressure, and the presence of
cosolvents and cosolutes. Such systems is therefore expected to show a
local response in structure due to the transport process. The structure
of the system is analysed in terms of a local equilibrium description.
The main focus is on systems with the propensity of undergoing an
internal phase separation. In this case there is a particularly strong
coupling between the diffusion... (More) - The relation between structure and diffusive transport at steady-state
is investigated theoretically for amphiphilic systems. Amphiphilic
systems typically show a large response to moderate changes in control
parameters, such as temperature, osmotic pressure, and the presence of
cosolvents and cosolutes. Such systems is therefore expected to show a
local response in structure due to the transport process. The structure
of the system is analysed in terms of a local equilibrium description.
The main focus is on systems with the propensity of undergoing an
internal phase separation. In this case there is a particularly strong
coupling between the diffusion process(es) and the local structure of
the system, which can lead to non-linear behaviour.
Specific applications include diffusive transport through the outermost
layer of human skin, the stratum corneum, where the possibility of a
phase change of the stratum corneum lipids could explain experimental
observations of a non-linear behaviour of the water transport. A model
for the formation of a gradient in pH over the stratum corneum is also
presented in terms of the diffusive transport of water and carbon
dioxide. Another application is film formation at the air-liquid
interface of surfactant-water systems undergoing evaporation. A study
showing that the structure of the surfactant layer lining the alveoli is
functionally beneficial for the diffusive transport of oxygen is also
presented. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1390787
- author
- Åberg, Christoffer LU
- supervisor
-
- Håkan Wennerström LU
- Emma Sparr LU
- opponent
-
- Dr Kabalnov, Alexey, Hewlett Packard, San Diego, USA
- organization
- publishing date
- 2009
- type
- Thesis
- publication status
- published
- subject
- keywords
- film formation, lung surfactant, skin surface pH, stratum corneum, responding membrane, diffusive transport, phase transition
- pages
- 162 pages
- defense location
- Hörsal C, Kemicentrum
- defense date
- 2009-06-04 10:30:00
- ISBN
- 978-91-7422-221-0
- language
- English
- LU publication?
- yes
- id
- 58bf706d-4929-4977-9a9c-ed7b1dbc006f (old id 1390787)
- date added to LUP
- 2016-04-04 13:06:28
- date last changed
- 2018-11-21 21:12:12
@phdthesis{58bf706d-4929-4977-9a9c-ed7b1dbc006f,
abstract = {{The relation between structure and diffusive transport at steady-state<br/><br>
is investigated theoretically for amphiphilic systems. Amphiphilic<br/><br>
systems typically show a large response to moderate changes in control<br/><br>
parameters, such as temperature, osmotic pressure, and the presence of<br/><br>
cosolvents and cosolutes. Such systems is therefore expected to show a<br/><br>
local response in structure due to the transport process. The structure<br/><br>
of the system is analysed in terms of a local equilibrium description.<br/><br>
The main focus is on systems with the propensity of undergoing an<br/><br>
internal phase separation. In this case there is a particularly strong<br/><br>
coupling between the diffusion process(es) and the local structure of<br/><br>
the system, which can lead to non-linear behaviour.<br/><br>
<br/><br>
Specific applications include diffusive transport through the outermost<br/><br>
layer of human skin, the stratum corneum, where the possibility of a<br/><br>
phase change of the stratum corneum lipids could explain experimental<br/><br>
observations of a non-linear behaviour of the water transport. A model<br/><br>
for the formation of a gradient in pH over the stratum corneum is also<br/><br>
presented in terms of the diffusive transport of water and carbon<br/><br>
dioxide. Another application is film formation at the air-liquid<br/><br>
interface of surfactant-water systems undergoing evaporation. A study<br/><br>
showing that the structure of the surfactant layer lining the alveoli is<br/><br>
functionally beneficial for the diffusive transport of oxygen is also<br/><br>
presented.}},
author = {{Åberg, Christoffer}},
isbn = {{978-91-7422-221-0}},
keywords = {{film formation; lung surfactant; skin surface pH; stratum corneum; responding membrane; diffusive transport; phase transition}},
language = {{eng}},
school = {{Lund University}},
title = {{Steady-State Diffusion in Complex Amphiphilic Films}},
url = {{https://lup.lub.lu.se/search/files/6053594/1390999.pdf}},
year = {{2009}},
}