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Macromolecular Drug Delivery: Basic Principles and Therapeutic Applications.

Belting, Mattias LU and Wittrup, Anders LU (2009) In Molecular Biotechnology 43. p.89-94
Abstract
Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on e.g., polymer chemistry, cell biology, nano technology, systems biology, advanced imaging methods, and clinical medicine. This poses obvious challenges to the scientific community, but also provides opportunities for the unexpected at the interface between different disciplines. This review summarizes recent studies of macromolecular delivery that should be of interest to researchers involved in... (More)
Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on e.g., polymer chemistry, cell biology, nano technology, systems biology, advanced imaging methods, and clinical medicine. This poses obvious challenges to the scientific community, but also provides opportunities for the unexpected at the interface between different disciplines. This review summarizes recent studies of macromolecular delivery that should be of interest to researchers involved in macromolecular drug synthesis as well as in vitro and in vivo drug delivery studies. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Molecular Biotechnology
volume
43
pages
89 - 94
publisher
Humana Press
external identifiers
  • WOS:000269205900011
  • PMID:19475521
  • Scopus:70350520554
ISSN
1559-0305
DOI
10.1007/s12033-009-9185-5
language
English
LU publication?
yes
id
48f25c46-2f94-4dc5-affa-6f5e79df7f21 (old id 1411932)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19475521?dopt=Abstract
date added to LUP
2009-06-03 14:20:54
date last changed
2016-10-13 04:35:07
@misc{48f25c46-2f94-4dc5-affa-6f5e79df7f21,
  abstract     = {Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on e.g., polymer chemistry, cell biology, nano technology, systems biology, advanced imaging methods, and clinical medicine. This poses obvious challenges to the scientific community, but also provides opportunities for the unexpected at the interface between different disciplines. This review summarizes recent studies of macromolecular delivery that should be of interest to researchers involved in macromolecular drug synthesis as well as in vitro and in vivo drug delivery studies.},
  author       = {Belting, Mattias and Wittrup, Anders},
  issn         = {1559-0305},
  language     = {eng},
  pages        = {89--94},
  publisher    = {ARRAY(0x9096638)},
  series       = {Molecular Biotechnology},
  title        = {Macromolecular Drug Delivery: Basic Principles and Therapeutic Applications.},
  url          = {http://dx.doi.org/10.1007/s12033-009-9185-5},
  volume       = {43},
  year         = {2009},
}