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Cumulative delivery rate in an in vitro fertilization program with a single embryo transfer policy.

Sundström, Per and Saldeen, Pia LU (2009) In Acta Obstetricia et Gynecologica Scandinavica 88(6). p.700-706
Abstract
OBJECTIVE: To investigate the cumulative delivery rate for women completing three fresh embryo transfer cycles or giving birth after the first or second transfer cycle in an in vitro fertilization program with a single embryo transfer (SET) policy. SETTING: Privately run infertility clinic in southern Sweden (Skåne region). POPULATION: Four hundred fifty-three consecutive, unselected public patients beginning an ovum pick-up cycle between July 2002 and June 2004. METHOD: Retrospective, observational study. MAIN OUTCOME MEASURE: Cumulative delivery rates. RESULTS: Of 370 women who completed the study with up to three fresh ET cycles (90% SETs), 244 women (66%) progressed to delivery. Among the deliveries were three sets of twins (1%), one... (More)
OBJECTIVE: To investigate the cumulative delivery rate for women completing three fresh embryo transfer cycles or giving birth after the first or second transfer cycle in an in vitro fertilization program with a single embryo transfer (SET) policy. SETTING: Privately run infertility clinic in southern Sweden (Skåne region). POPULATION: Four hundred fifty-three consecutive, unselected public patients beginning an ovum pick-up cycle between July 2002 and June 2004. METHOD: Retrospective, observational study. MAIN OUTCOME MEASURE: Cumulative delivery rates. RESULTS: Of 370 women who completed the study with up to three fresh ET cycles (90% SETs), 244 women (66%) progressed to delivery. Among the deliveries were three sets of twins (1%), one dizygotic. Cumulative delivery rates showed significant differences relative to age <36 (71%) and >or=36 years (47%), and delivery rates relative to rank of ET cycle (first and second vs. third ET cycle - 35, 34, and 21% delivery rates, respectively). CONCLUSIONS: The 66% cumulative delivery rate is in accordance with rates in similar observational studies and in estimation studies, in which predominantly two embryos were used for transfer. The multiple delivery rate was low. We suggest that repeated SET cycles can be implemented on a large scale even in a primarily unselected patient population without compromising the outcome. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Obstetricia et Gynecologica Scandinavica
volume
88
issue
6
pages
700 - 706
publisher
Wiley-Blackwell
external identifiers
  • PMID:19455443
  • Scopus:66149148311
ISSN
1600-0412
DOI
10.1080/00016340902956939
language
English
LU publication?
yes
id
6019fc20-555d-4a95-96de-09229dc889fd (old id 1412122)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19455443?dopt=Abstract
date added to LUP
2009-06-04 09:22:58
date last changed
2016-10-13 04:25:28
@misc{6019fc20-555d-4a95-96de-09229dc889fd,
  abstract     = {OBJECTIVE: To investigate the cumulative delivery rate for women completing three fresh embryo transfer cycles or giving birth after the first or second transfer cycle in an in vitro fertilization program with a single embryo transfer (SET) policy. SETTING: Privately run infertility clinic in southern Sweden (Skåne region). POPULATION: Four hundred fifty-three consecutive, unselected public patients beginning an ovum pick-up cycle between July 2002 and June 2004. METHOD: Retrospective, observational study. MAIN OUTCOME MEASURE: Cumulative delivery rates. RESULTS: Of 370 women who completed the study with up to three fresh ET cycles (90% SETs), 244 women (66%) progressed to delivery. Among the deliveries were three sets of twins (1%), one dizygotic. Cumulative delivery rates showed significant differences relative to age &lt;36 (71%) and &gt;or=36 years (47%), and delivery rates relative to rank of ET cycle (first and second vs. third ET cycle - 35, 34, and 21% delivery rates, respectively). CONCLUSIONS: The 66% cumulative delivery rate is in accordance with rates in similar observational studies and in estimation studies, in which predominantly two embryos were used for transfer. The multiple delivery rate was low. We suggest that repeated SET cycles can be implemented on a large scale even in a primarily unselected patient population without compromising the outcome.},
  author       = {Sundström, Per and Saldeen, Pia},
  issn         = {1600-0412},
  language     = {eng},
  number       = {6},
  pages        = {700--706},
  publisher    = {ARRAY(0xcbc5a28)},
  series       = {Acta Obstetricia et Gynecologica Scandinavica},
  title        = {Cumulative delivery rate in an in vitro fertilization program with a single embryo transfer policy.},
  url          = {http://dx.doi.org/10.1080/00016340902956939},
  volume       = {88},
  year         = {2009},
}