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Translocation-related sarcomas.

Mertens, Fredrik LU ; Antonescu, Cristina R; Hohenberger, Peter; Ladanyi, Marc; Modena, Piergiorgio; D'Incalci, Maurizio; Casali, Paolo G; Aglietta, Massimo and Alvegård, Thor LU (2009) In Seminars in Oncology 36(4). p.312-323
Abstract
Sarcomas with chromosomal translocations represent only about one fourth of sarcoma diagnoses. However, like gastrointestinal stromal tumor (GIST), with its characteristic KIT or PDGFRA mutations, they are particularly interesting since they provide specific biological insights and mechanisms of action that may have an impact upon prognosis or therapy. These are mechanisms we are just beginning to exploit. In this section we will review the biology and clinical impact of translocation-associated sarcomas and review the clinical findings that have made a recent impact upon patients with these diverse diagnoses.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Seminars in Oncology
volume
36
issue
4
pages
312 - 323
publisher
W.B. Saunders Ltd
external identifiers
  • WOS:000268899600004
  • PMID:19664492
  • Scopus:67949088340
ISSN
0093-7754
DOI
10.1053/j.seminoncol.2009.06.004
language
English
LU publication?
yes
id
4a35f13f-db3d-45bc-aa09-64b1aee8a95e (old id 1469899)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19664492?dopt=Abstract
date added to LUP
2009-09-04 14:22:51
date last changed
2016-10-13 04:25:18
@misc{4a35f13f-db3d-45bc-aa09-64b1aee8a95e,
  abstract     = {Sarcomas with chromosomal translocations represent only about one fourth of sarcoma diagnoses. However, like gastrointestinal stromal tumor (GIST), with its characteristic KIT or PDGFRA mutations, they are particularly interesting since they provide specific biological insights and mechanisms of action that may have an impact upon prognosis or therapy. These are mechanisms we are just beginning to exploit. In this section we will review the biology and clinical impact of translocation-associated sarcomas and review the clinical findings that have made a recent impact upon patients with these diverse diagnoses.},
  author       = {Mertens, Fredrik and Antonescu, Cristina R and Hohenberger, Peter and Ladanyi, Marc and Modena, Piergiorgio and D'Incalci, Maurizio and Casali, Paolo G and Aglietta, Massimo and Alvegård, Thor},
  issn         = {0093-7754},
  language     = {eng},
  number       = {4},
  pages        = {312--323},
  publisher    = {ARRAY(0x60040a0)},
  series       = {Seminars in Oncology},
  title        = {Translocation-related sarcomas.},
  url          = {http://dx.doi.org/10.1053/j.seminoncol.2009.06.004},
  volume       = {36},
  year         = {2009},
}