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Incidence of psychotic disorders in the 50 year follow up of the Lundby population.

Bogren, Mats LU ; Mattisson, Cecilia LU ; Isberg, Per-Erik LU ; Munk-Jørgensen, Povl and Nettelbladt, Per LU (2010) In The Australian and New Zealand journal of psychiatry 44(1). p.31-39
Abstract
OBJECTIVE: The aim of the present study was to analyse first incidence of psychotic disorders in the Lundby population during a 50 year period by comparing male and female age at onset, overall incidence rates and age-specific incidence rates. METHOD: The Lundby Study is a prospective study of the mental health of a complete community population (n = 3563), which was followed from 1947 to 1997. Data from interviews, registers, case files and key informants were accumulated via four waves of field work (1947 1957, 1972 and 1997). Mean and median age at onset, and overall and age-specific incidence rates, for the first episodes of major groups of psychotic disorders according to the DSM-IV were calculated (the major groups were: any... (More)
OBJECTIVE: The aim of the present study was to analyse first incidence of psychotic disorders in the Lundby population during a 50 year period by comparing male and female age at onset, overall incidence rates and age-specific incidence rates. METHOD: The Lundby Study is a prospective study of the mental health of a complete community population (n = 3563), which was followed from 1947 to 1997. Data from interviews, registers, case files and key informants were accumulated via four waves of field work (1947 1957, 1972 and 1997). Mean and median age at onset, and overall and age-specific incidence rates, for the first episodes of major groups of psychotic disorders according to the DSM-IV were calculated (the major groups were: any psychotic disorder, psychotic disorder due to a general medical condition, substance-induced psychotic disorder, non-affective psychotic disorder, schizophrenia, other non-affective psychotic disorder and affective psychotic disorder). Male-female differences in mean ages at onset and overall incidence rates were tested. Male-female differences in incidence by age patterns were described. RESULTS: The overall 50 year incidence rate in male subjects was higher than in female subjects for substance-induced psychotic disorder, but for the other disorders the overall rates did not differ significantly between the sexes. The male mean age at onset was lower than that for female subjects for any psychotic disorder, psychotic disorder due to a general medical condition, non-affective psychotic disorder and schizophrenia. Male and female subjects had different incidences by age patterns for any psychotic disorder, non-affective psychotic disorder, schizophrenia and other non-affective psychotic disorder, with a male preponderance among early-onset cases, and a female preponderance among late-onset cases. CONCLUSION: The differences in incidence between the sexes in this 50 year follow up may indicate psychotic disorder-delaying mechanisms in female subjects, or different aetiologies of psychosis in male and female subjects. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Australian and New Zealand journal of psychiatry
volume
44
issue
1
pages
31 - 39
external identifiers
  • WOS:000274155800004
  • PMID:20073565
  • Scopus:75149194878
ISSN
1440-1614
DOI
10.3109/00048670903393647
language
English
LU publication?
yes
id
88c6d891-a9c9-44b6-ac5d-5b04337fabdf (old id 1541079)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20073565?dopt=Abstract
date added to LUP
2010-02-02 13:31:06
date last changed
2016-10-13 04:24:06
@misc{88c6d891-a9c9-44b6-ac5d-5b04337fabdf,
  abstract     = {OBJECTIVE: The aim of the present study was to analyse first incidence of psychotic disorders in the Lundby population during a 50 year period by comparing male and female age at onset, overall incidence rates and age-specific incidence rates. METHOD: The Lundby Study is a prospective study of the mental health of a complete community population (n = 3563), which was followed from 1947 to 1997. Data from interviews, registers, case files and key informants were accumulated via four waves of field work (1947 1957, 1972 and 1997). Mean and median age at onset, and overall and age-specific incidence rates, for the first episodes of major groups of psychotic disorders according to the DSM-IV were calculated (the major groups were: any psychotic disorder, psychotic disorder due to a general medical condition, substance-induced psychotic disorder, non-affective psychotic disorder, schizophrenia, other non-affective psychotic disorder and affective psychotic disorder). Male-female differences in mean ages at onset and overall incidence rates were tested. Male-female differences in incidence by age patterns were described. RESULTS: The overall 50 year incidence rate in male subjects was higher than in female subjects for substance-induced psychotic disorder, but for the other disorders the overall rates did not differ significantly between the sexes. The male mean age at onset was lower than that for female subjects for any psychotic disorder, psychotic disorder due to a general medical condition, non-affective psychotic disorder and schizophrenia. Male and female subjects had different incidences by age patterns for any psychotic disorder, non-affective psychotic disorder, schizophrenia and other non-affective psychotic disorder, with a male preponderance among early-onset cases, and a female preponderance among late-onset cases. CONCLUSION: The differences in incidence between the sexes in this 50 year follow up may indicate psychotic disorder-delaying mechanisms in female subjects, or different aetiologies of psychosis in male and female subjects.},
  author       = {Bogren, Mats and Mattisson, Cecilia and Isberg, Per-Erik and Munk-Jørgensen, Povl and Nettelbladt, Per},
  issn         = {1440-1614},
  language     = {eng},
  number       = {1},
  pages        = {31--39},
  series       = {The Australian and New Zealand journal of psychiatry},
  title        = {Incidence of psychotic disorders in the 50 year follow up of the Lundby population.},
  url          = {http://dx.doi.org/10.3109/00048670903393647},
  volume       = {44},
  year         = {2010},
}