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Open chromatin and diabetes risk.

Groop, Leif LU (2010) In Nature Genetics 42(3). p.190-192
Abstract
A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes-associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and shows allele-specific enhancer activity, suggesting a potential mechanism for this disease association.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nature Genetics
volume
42
issue
3
pages
190 - 192
publisher
Nature Publishing Group
external identifiers
  • WOS:000274912400003
  • PMID:20179731
  • Scopus:77649099195
ISSN
1546-1718
DOI
10.1038/ng0310-190
language
English
LU publication?
yes
id
b0b03479-1d37-48d3-996a-8213a62f15d1 (old id 1552313)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20179731?dopt=Abstract
date added to LUP
2010-03-03 13:33:37
date last changed
2016-10-16 04:15:11
@misc{b0b03479-1d37-48d3-996a-8213a62f15d1,
  abstract     = {A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes-associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and shows allele-specific enhancer activity, suggesting a potential mechanism for this disease association.},
  author       = {Groop, Leif},
  issn         = {1546-1718},
  language     = {eng},
  number       = {3},
  pages        = {190--192},
  publisher    = {ARRAY(0x94fe028)},
  series       = {Nature Genetics},
  title        = {Open chromatin and diabetes risk.},
  url          = {http://dx.doi.org/10.1038/ng0310-190},
  volume       = {42},
  year         = {2010},
}