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Thrombotic occlusion of all left coronary branches in a young woman with severe ulcerative colitis

Gustavsson, Carl Gunnar LU ; Svensson, Peter LU ; Hertervig, Erik LU ; Lennart, Sandhall; Peter, Hårdhammar; Natascia, Malcevschi-Lind and Olsson, Sven-Erik LU (2011) In ISRN Cardiology
Abstract
Background. The thrombosis risk is increased in active ulcerative colitis. The limited number of reported complications have

predominantly been cerebrovascular but other vessel territories may also be affected. Patient. During a severe attack of ulcerative

colitis a 37-year-old woman suffered occlusion of all left coronary artery branches. Serial angiographies showed progressive

recanalisation of the coronary arteries during anticoagulation, but no atherosclerotic stenosis. The cause of infarction was thus

considered to be an extensive coronary thrombosis. However, a large battery of blood tests failed to identify any procoagulant

abnormality. Conclusion. Evidence is now accumulating that the... (More)
Background. The thrombosis risk is increased in active ulcerative colitis. The limited number of reported complications have

predominantly been cerebrovascular but other vessel territories may also be affected. Patient. During a severe attack of ulcerative

colitis a 37-year-old woman suffered occlusion of all left coronary artery branches. Serial angiographies showed progressive

recanalisation of the coronary arteries during anticoagulation, but no atherosclerotic stenosis. The cause of infarction was thus

considered to be an extensive coronary thrombosis. However, a large battery of blood tests failed to identify any procoagulant

abnormality. Conclusion. Evidence is now accumulating that the increased thrombosis risk also may involve the coronary arteries,

even in young patients. To the best of our knowledge this is the third reported case ofmyocardial infarction despite angiographically

normal coronary arteries in a patient with active ulcerative colitis. The extent of affected myocardiumwas in this case exceptionally

large. (Less)
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organization
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Contribution to journal
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published
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ISRN Cardiology
publisher
Hindawi Publishing Corporation
DOI
10.5402/2011/134631
language
English
LU publication?
yes
id
4c6b8836-633a-43b1-873e-54d97d22d6d4 (old id 1940487)
alternative location
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279691/
http://www.hindawi.com/isrn/cardiology/2011/134631/
http://www.ncbi.nlm.nih.gov/pubmed/22347627
date added to LUP
2013-05-14 15:18:15
date last changed
2016-09-20 03:28:31
@misc{4c6b8836-633a-43b1-873e-54d97d22d6d4,
  abstract     = {Background. The thrombosis risk is increased in active ulcerative colitis. The limited number of reported complications have<br/><br>
predominantly been cerebrovascular but other vessel territories may also be affected. Patient. During a severe attack of ulcerative<br/><br>
colitis a 37-year-old woman suffered occlusion of all left coronary artery branches. Serial angiographies showed progressive<br/><br>
recanalisation of the coronary arteries during anticoagulation, but no atherosclerotic stenosis. The cause of infarction was thus<br/><br>
considered to be an extensive coronary thrombosis. However, a large battery of blood tests failed to identify any procoagulant<br/><br>
abnormality. Conclusion. Evidence is now accumulating that the increased thrombosis risk also may involve the coronary arteries,<br/><br>
even in young patients. To the best of our knowledge this is the third reported case ofmyocardial infarction despite angiographically<br/><br>
normal coronary arteries in a patient with active ulcerative colitis. The extent of affected myocardiumwas in this case exceptionally<br/><br>
large.},
  author       = {Gustavsson, Carl Gunnar and Svensson, Peter and Hertervig, Erik and Lennart, Sandhall and Peter, Hårdhammar and Natascia, Malcevschi-Lind and Olsson, Sven-Erik},
  language     = {eng},
  publisher    = {ARRAY(0x9ab4b40)},
  series       = {ISRN Cardiology},
  title        = {Thrombotic occlusion of all left coronary branches in a young woman with severe ulcerative colitis},
  url          = {http://dx.doi.org/10.5402/2011/134631},
  year         = {2011},
}