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Effects of exposure to indoor nano-sized particles on heart rate variability

Hagerman, Inger; Isaxon, Christina LU ; Dierschke, Katrin LU ; Wierzbicka, Aneta LU ; Pagels, Joakim LU ; Gudmundsson, Anders LU ; Nielsen, Jörn LU ; Berglund, Margareta; Assarsson, Eva LU and Andersson, Ulla B LU , et al. (2011)
Abstract
Background

Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in fine particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups.

Aim of study

To evaluate the impact of nano-sized indoor air particles on HRV.

Methods

All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene+ozone-reactions or filtered air in a double-blind cross over fashion. 22 healthy females were investigated during 10 minute... (More)
Background

Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in fine particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups.

Aim of study

To evaluate the impact of nano-sized indoor air particles on HRV.

Methods

All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene+ozone-reactions or filtered air in a double-blind cross over fashion. 22 healthy females were investigated during 10 minute periods at different exposures and HRV were computed for various spectral components.

Results

Heart rate was unchanged from baseline values in all groups during all experimental settings. Compared to filtered air, burning candle tended to decrease the power in both high (HF) and low (LF) spectral band but only in HF during terpene+ozone.

Conclusions

Exposure to nano-sized particles of burning candles or terpene+ozone seem to have an impact on heart rate variability, mediated by different aspects of autonomic cardiovascular control.

Practical implications

This study indicate that the HRV method may be used for information on physiological response of exposure different nano-sized particles and contribute to the understanding of mechanisms behind effects of particle exposures (Less)
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organization
publishing date
type
Working Paper
publication status
unpublished
subject
keywords
Airborne particles, nano particles, HRV, cardiovascular, autonomic control
pages
22 pages
language
English
LU publication?
yes
id
b4d72c30-d2e4-495a-9367-d0602e76e2df (old id 1951437)
date added to LUP
2011-05-12 15:14:16
date last changed
2016-04-16 11:36:44
@misc{b4d72c30-d2e4-495a-9367-d0602e76e2df,
  abstract     = {Background<br/><br>
Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in fine particles with diameter &lt; 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups.<br/><br>
Aim of study<br/><br>
To evaluate the impact of nano-sized indoor air particles on HRV. <br/><br>
Methods<br/><br>
All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene+ozone-reactions or filtered air in a double-blind cross over fashion. 22 healthy females were investigated during 10 minute periods at different exposures and HRV were computed for various spectral components.<br/><br>
Results<br/><br>
Heart rate was unchanged from baseline values in all groups during all experimental settings. Compared to filtered air, burning candle tended to decrease the power in both high (HF) and low (LF) spectral band but only in HF during terpene+ozone. <br/><br>
Conclusions<br/><br>
 Exposure to nano-sized particles of burning candles or terpene+ozone seem to have an impact on heart rate variability, mediated by different aspects of autonomic cardiovascular control.<br/><br>
Practical implications<br/><br>
This study indicate that the HRV method may be used for information on physiological response of exposure different nano-sized particles and contribute to the understanding of mechanisms behind effects of particle exposures},
  author       = {Hagerman, Inger and Isaxon, Christina and Dierschke, Katrin and Wierzbicka, Aneta and Pagels, Joakim and Gudmundsson, Anders and Nielsen, Jörn and Berglund, Margareta and Assarsson, Eva and Andersson, Ulla B and Jönsson, Bo A and Bohgard, Mats},
  keyword      = {Airborne particles,nano particles,HRV,cardiovascular,autonomic control},
  language     = {eng},
  pages        = {22},
  title        = {Effects of exposure to indoor nano-sized particles on heart rate variability},
  year         = {2011},
}