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A MRI and polarized gases compatible respirator and gas administrator for the study of the small animal lung : volume measurement and control

Kyriazis, Angelos; Perez de Alejo, Rigoberto; Rodriguez, Ignacio; Olsson, Lars E LU and Ruiz-Cabello, Jesus (2010) In IEEE Transactions on Biomedical Engineering 57(7). p.9-1745
Abstract

We have developed over the past years an experimental magnetic resonance imaging (MRI) and polarized gases compatible mechanical respirator for the study of the small experimental animal. The respirator has been successfully used for experiments both in the MRI setting for polarized (3)He, (19)F, and proton imaging as well as for functional measurements of the lungs. The new main pneumatic valve with the two integrated sensors for simultaneous lung pressure and volume measurements and the proportional valve to set the tidal volume of the respiration are described. It is shown how the device measures and controls the tidal volume of the lungs.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Animals, Biomedical Research, Gases, Lung Compliance, Lung Volume Measurements, Magnetic Resonance Imaging, Mice, Ventilators, Mechanical
in
IEEE Transactions on Biomedical Engineering
volume
57
issue
7
pages
5 pages
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • Scopus:77953800531
ISSN
0018-9294
DOI
10.1109/TBME.2010.2042596
language
English
LU publication?
yes
id
1a926b23-bc24-4ad6-a066-8576f850d99b
date added to LUP
2016-08-16 12:09:40
date last changed
2016-10-13 05:12:15
@misc{1a926b23-bc24-4ad6-a066-8576f850d99b,
  abstract     = {<p>We have developed over the past years an experimental magnetic resonance imaging (MRI) and polarized gases compatible mechanical respirator for the study of the small experimental animal. The respirator has been successfully used for experiments both in the MRI setting for polarized (3)He, (19)F, and proton imaging as well as for functional measurements of the lungs. The new main pneumatic valve with the two integrated sensors for simultaneous lung pressure and volume measurements and the proportional valve to set the tidal volume of the respiration are described. It is shown how the device measures and controls the tidal volume of the lungs.</p>},
  author       = {Kyriazis, Angelos and Perez de Alejo, Rigoberto and Rodriguez, Ignacio and Olsson, Lars E and Ruiz-Cabello, Jesus},
  issn         = {0018-9294},
  keyword      = {Animals,Biomedical Research,Gases,Lung Compliance,Lung Volume Measurements,Magnetic Resonance Imaging,Mice,Ventilators, Mechanical},
  language     = {eng},
  number       = {7},
  pages        = {9--1745},
  publisher    = {ARRAY(0x8f84f28)},
  series       = {IEEE Transactions on Biomedical Engineering},
  title        = {A MRI and polarized gases compatible respirator and gas administrator for the study of the small animal lung : volume measurement and control},
  url          = {http://dx.doi.org/10.1109/TBME.2010.2042596},
  volume       = {57},
  year         = {2010},
}