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Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers

Ivarsson, K; Olsrud, J; Sturesson, C; Moller, P. H; Persson, Bertil R LU and Tranberg, K. G (1998) In Lasers in Surgery and Medicine 22(2). p.86-96
Abstract
Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on... (More)
Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on the bioheat equation was used to calculate the temperature distributions. Results: Temperature regulation was excellent with a tendency towards better regulation in the four-fiber than in the single-fiber experiments. Agreement between calculated and measured temperatures was good. The coagulated (>55 degrees C) and hyperthermic (>45 degrees C) volumes were 6 and 10-11 times larger, respectively, with four-fibers than with a single fiber. Conclusion: It is concluded that the stepwise power regulation system was efficient in maintaining a stable target temperature. The results indicate that the system can produce lesion volumes adequate for treating a relatively large tumor in a single session and that computer simulation may be useful for predicting temperature distribution. (C) 1998 Wiley-Liss, Inc. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Lasers in Surgery and Medicine
volume
22
issue
2
pages
86 - 96
publisher
John Wiley & Sons
external identifiers
  • Scopus:0031937140
ISSN
0196-8092
DOI
10.1002/(SICI)1096-9101(1998)22:2<86::AID-LSM4>3.0.CO;2-S
language
English
LU publication?
yes
id
29291337-de7b-48af-9a9c-69d1c6fab51c (old id 2258426)
date added to LUP
2012-02-20 22:59:56
date last changed
2016-10-13 04:23:48
@misc{29291337-de7b-48af-9a9c-69d1c6fab51c,
  abstract     = {Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in ground bovine muscle using either a single laser fiber or four-fibers. The target temperature at one (feedback) thermistor, placed 5 mm from one of the laser fibers, was set to 50 degrees C and was maintained by means of stepwise power regulation. The temperature distribution was monitored using multiple thermistor probes. A numerical model based on the bioheat equation was used to calculate the temperature distributions. Results: Temperature regulation was excellent with a tendency towards better regulation in the four-fiber than in the single-fiber experiments. Agreement between calculated and measured temperatures was good. The coagulated (&gt;55 degrees C) and hyperthermic (&gt;45 degrees C) volumes were 6 and 10-11 times larger, respectively, with four-fibers than with a single fiber. Conclusion: It is concluded that the stepwise power regulation system was efficient in maintaining a stable target temperature. The results indicate that the system can produce lesion volumes adequate for treating a relatively large tumor in a single session and that computer simulation may be useful for predicting temperature distribution. (C) 1998 Wiley-Liss, Inc.},
  author       = {Ivarsson, K and Olsrud, J and Sturesson, C and Moller, P. H and Persson, Bertil R and Tranberg, K. G},
  issn         = {0196-8092},
  language     = {eng},
  number       = {2},
  pages        = {86--96},
  publisher    = {ARRAY(0x89e6e48)},
  series       = {Lasers in Surgery and Medicine},
  title        = {Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers},
  url          = {http://dx.doi.org/10.1002/(SICI)1096-9101(1998)22:2<86::AID-LSM4>3.0.CO;2-S},
  volume       = {22},
  year         = {1998},
}