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Complex avoidance behavior and its neurochemical regulation in the land snail Cepea numerals

Dyakonova, V. E.; Elofsson, Rolf LU ; Carlberg, M and Sakharov, D A (1995) In General Pharmacology 26. p.773-777
Abstract
.
1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.
2.
2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the searching behaviour. Opposite effects were achieved by injection of antisera to the enkephalins.
3.
3. Both retraction and searching behaviours were potentiated by 5-HT. Methysergide antagonized the effects of the enkephalins on the searching behaviour.
4.
4. We conclude that endogenous opioids act antagonistic to... (More)
.
1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.
2.
2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the searching behaviour. Opposite effects were achieved by injection of antisera to the enkephalins.
3.
3. Both retraction and searching behaviours were potentiated by 5-HT. Methysergide antagonized the effects of the enkephalins on the searching behaviour.
4.
4. We conclude that endogenous opioids act antagonistic to FMRFamide in the neuronally controlled switch between passive and active avoidance behaviour. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Land snail, opioids, FMRFamide, serotonin, avoidance behaviour
in
General Pharmacology
volume
26
pages
773 - 777
publisher
Elsevier
ISSN
0306-3623
DOI
10.1016/0306-3623(94)00263-M
language
English
LU publication?
yes
id
225ce9ca-4358-450f-a04b-1f2e3e877366
date added to LUP
2016-10-31 21:34:38
date last changed
2016-11-17 15:02:14
@misc{225ce9ca-4358-450f-a04b-1f2e3e877366,
  abstract     = {.<br/>1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.<br/>2.<br/>2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the searching behaviour. Opposite effects were achieved by injection of antisera to the enkephalins.<br/>3.<br/>3. Both retraction and searching behaviours were potentiated by 5-HT. Methysergide antagonized the effects of the enkephalins on the searching behaviour.<br/>4.<br/>4. We conclude that endogenous opioids act antagonistic to FMRFamide in the neuronally controlled switch between passive and active avoidance behaviour.},
  author       = {Dyakonova, V. E. and Elofsson, Rolf and Carlberg, M and Sakharov, D A},
  issn         = {0306-3623},
  keyword      = {Land snail,opioids,FMRFamide,serotonin,avoidance behaviour},
  language     = {eng},
  pages        = {773--777},
  publisher    = {ARRAY(0x7c3e2c0)},
  series       = {General Pharmacology},
  title        = {Complex avoidance behavior and its neurochemical regulation in the land snail Cepea numerals},
  url          = {http://dx.doi.org/10.1016/0306-3623(94)00263-M},
  volume       = {26},
  year         = {1995},
}