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The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

Dustler, Magnus LU ; Förnvik, Daniel LU ; Timberg, Pontus LU ; Petersson, Hannie LU ; Tingberg, Anders LU and Zackrisson, Sophia LU (2016) 13th International Workshop on Breast Imaging, IWDM 2016 In Breast Imaging 9699. p.282-288
Abstract

Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P =... (More)

Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Elastography, Mammography, Mechanical imaging, Screening
in
Breast Imaging
editor
Tingberg, Anders ; Lång, Kristina and Timberg, Pontus
volume
9699
pages
7 pages
publisher
Springer Verlag
conference name
13th International Workshop on Breast Imaging, IWDM 2016
external identifiers
  • Scopus:84977553497
ISSN
03029743
16113349
ISBN
9783319415451
DOI
10.1007/978-3-319-41546-8_36
language
English
LU publication?
yes
id
2267bf40-208f-4d18-8782-dc370f5febc3
date added to LUP
2016-07-25 12:47:06
date last changed
2016-10-05 08:43:55
@misc{2267bf40-208f-4d18-8782-dc370f5febc3,
  abstract     = {<p>Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.</p>},
  author       = {Dustler, Magnus and Förnvik, Daniel and Timberg, Pontus and Petersson, Hannie and Tingberg, Anders and Zackrisson, Sophia},
  editor       = {Tingberg, Anders  and Lång, Kristina and Timberg, Pontus},
  isbn         = {9783319415451},
  issn         = {03029743},
  keyword      = {Elastography,Mammography,Mechanical imaging,Screening},
  language     = {eng},
  pages        = {282--288},
  publisher    = {ARRAY(0xa0d7dc0)},
  series       = {Breast Imaging},
  title        = {The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography},
  url          = {http://dx.doi.org/10.1007/978-3-319-41546-8_36},
  volume       = {9699},
  year         = {2016},
}