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The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.

Nilsson, Karin LU ; Gustafson, Lars LU and Hultberg, Björn LU (2012) In Dementia and Geriatric Cognitive Disorders Extra 2. p.10-18
Abstract
BACKGROUND:

Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.



METHOD:

In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.



RESULTS AND CONCLUSION:

Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease... (More)
BACKGROUND:

Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.



METHOD:

In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.



RESULTS AND CONCLUSION:

Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dementia and Geriatric Cognitive Disorders Extra
volume
2
pages
10 - 18
publisher
Karger
external identifiers
  • PMID:22479261
ISSN
1664-5464
DOI
10.1159/000334997
language
English
LU publication?
yes
id
f11d08e8-ad91-4917-ae93-8e3b89b2c1b0 (old id 2519765)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22479261?dopt=Abstract
date added to LUP
2012-05-06 14:25:04
date last changed
2016-04-16 06:21:00
@misc{f11d08e8-ad91-4917-ae93-8e3b89b2c1b0,
  abstract     = {BACKGROUND:<br/><br>
Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.<br/><br>
<br/><br>
METHOD:<br/><br>
In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.<br/><br>
<br/><br>
RESULTS AND CONCLUSION:<br/><br>
Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease.},
  author       = {Nilsson, Karin and Gustafson, Lars and Hultberg, Björn},
  issn         = {1664-5464},
  language     = {eng},
  pages        = {10--18},
  publisher    = {ARRAY(0x80f1e70)},
  series       = {Dementia and Geriatric Cognitive Disorders Extra},
  title        = {The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.},
  url          = {http://dx.doi.org/10.1159/000334997},
  volume       = {2},
  year         = {2012},
}