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Nickel-doped agarose gel phantoms in MR imaging

Christoffersson, J O; Olsson, L E LU and Sjöberg, S (1991) In Acta Radiologica 32(5). p.31-426
Abstract

A method for the production of a tissue-mimicking phantom material for MR imaging is described. The material consists of a nickel-doped agarose gel. The T1 and T2 values of the gel can be varied independently by changing the relative amounts of nickel and agarose. Practically any T1 and T2 combination of clinical interest can be obtained. The long-term stability was studied and found to be good. The relaxation times were estimated using an MR analyzer. The accuracy and the reproducibility of these measurements were evaluated and found to be reassuring. Gel phantoms were also scanned in an MR unit. The signal strength of an inversion recovery sequence was evaluated using the gel phantoms in order to verify their usefulness. These... (More)

A method for the production of a tissue-mimicking phantom material for MR imaging is described. The material consists of a nickel-doped agarose gel. The T1 and T2 values of the gel can be varied independently by changing the relative amounts of nickel and agarose. Practically any T1 and T2 combination of clinical interest can be obtained. The long-term stability was studied and found to be good. The relaxation times were estimated using an MR analyzer. The accuracy and the reproducibility of these measurements were evaluated and found to be reassuring. Gel phantoms were also scanned in an MR unit. The signal strength of an inversion recovery sequence was evaluated using the gel phantoms in order to verify their usefulness. These measurements were compared to theory with good agreement. Furthermore, tissue-equivalent phantoms were made. Gels resembling gray matter, white matter, and CSF were scanned. Comparisons with clinical in vivo scans, as well as calculated levels were made. It is anticipated that the gel phantoms described here will be useful in quality assurance as well as in pulse sequence optimization.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Gels, Magnetic Resonance Imaging, Models, Structural, Nickel, Sepharose
in
Acta Radiologica
volume
32
issue
5
pages
6 pages
publisher
John Wiley & Sons
external identifiers
  • Scopus:0026040266
ISSN
0284-1851
DOI
10.3109/02841859109177599
language
English
LU publication?
yes
id
2895ca29-1b79-4bb5-9f7b-f19857cb3bb7
date added to LUP
2016-08-16 12:17:17
date last changed
2016-09-15 11:08:19
@misc{2895ca29-1b79-4bb5-9f7b-f19857cb3bb7,
  abstract     = {<p>A method for the production of a tissue-mimicking phantom material for MR imaging is described. The material consists of a nickel-doped agarose gel. The T1 and T2 values of the gel can be varied independently by changing the relative amounts of nickel and agarose. Practically any T1 and T2 combination of clinical interest can be obtained. The long-term stability was studied and found to be good. The relaxation times were estimated using an MR analyzer. The accuracy and the reproducibility of these measurements were evaluated and found to be reassuring. Gel phantoms were also scanned in an MR unit. The signal strength of an inversion recovery sequence was evaluated using the gel phantoms in order to verify their usefulness. These measurements were compared to theory with good agreement. Furthermore, tissue-equivalent phantoms were made. Gels resembling gray matter, white matter, and CSF were scanned. Comparisons with clinical in vivo scans, as well as calculated levels were made. It is anticipated that the gel phantoms described here will be useful in quality assurance as well as in pulse sequence optimization.</p>},
  author       = {Christoffersson, J O and Olsson, L E and Sjöberg, S},
  issn         = {0284-1851},
  keyword      = {Gels,Magnetic Resonance Imaging,Models, Structural,Nickel,Sepharose},
  language     = {eng},
  number       = {5},
  pages        = {31--426},
  publisher    = {ARRAY(0x75b3a58)},
  series       = {Acta Radiologica},
  title        = {Nickel-doped agarose gel phantoms in MR imaging},
  url          = {http://dx.doi.org/10.3109/02841859109177599},
  volume       = {32},
  year         = {1991},
}