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Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.

Saxne, Tore LU ; Palladino, Michael; Heinegård, Dick LU ; Talal, Norman and Wollheim, Frank LU (1988) In Arthritis and Rheumatism 31(8). p.1041-1045
Abstract
Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor α (TNFα). Seven of 12 sera from RA patients contained TNFα, while only 1 of those from reactive arthritis patients was positive. Gamma-interferon was detected in the synovial fluids and sera of only the RA patients. Tumor necrosis factor β was not detected in any sera or synovial fluids. RA patients with detectable TNFα had higher erythrocyte sedimentation rates and synovial fluid leukocyte counts.
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author
organization
publishing date
type
Contribution to journal
publication status
published
in
Arthritis and Rheumatism
volume
31
issue
8
pages
1041 - 1045
publisher
John Wiley & Sons
ISSN
0004-3591
language
English
LU publication?
yes
id
2cb0f821-d861-4ad3-a2c0-cea40268079a
date added to LUP
2016-05-06 16:02:37
date last changed
2016-06-13 10:23:09
@misc{2cb0f821-d861-4ad3-a2c0-cea40268079a,
  abstract     = {Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor α (TNFα). Seven of 12 sera from RA patients contained TNFα, while only 1 of those from reactive arthritis patients was positive. Gamma-interferon was detected in the synovial fluids and sera of only the RA patients. Tumor necrosis factor β was not detected in any sera or synovial fluids. RA patients with detectable TNFα had higher erythrocyte sedimentation rates and synovial fluid leukocyte counts.},
  author       = {Saxne, Tore and Palladino, Michael and Heinegård, Dick and Talal, Norman and Wollheim, Frank},
  issn         = {0004-3591},
  language     = {eng},
  number       = {8},
  pages        = {1041--1045},
  publisher    = {ARRAY(0x874abd0)},
  series       = {Arthritis and Rheumatism},
  title        = {Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.},
  volume       = {31},
  year         = {1988},
}