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CT angiography of intracranial arterial vessels: impact of tube voltage and contrast media concentration on image quality.

Ramgren, Birgitta LU ; Björkman-Burtscher, Isabella LU ; Holtås, Stig and Siemund, Roger LU (2012) In Acta radiologica (Stockholm, Sweden : 1987) 53(8). p.929-934
Abstract
Background:

Computed tomography angiography (CTA) of intracranial arteries has high demands on image quality. Important parameters influencing vessel enhancement are injection rate, concentration of contrast media and tube voltage.



Purpose:

To evaluate the impact of an increase of contrast media concentration from 300 to 400 mg iodine/mL (mgI/mL) and the effect of a decrease of tube voltage from 120 to 90 kVp on vessel attenuation and image quality in CT angiography of intracranial arteries.



Material and Methods

Sixty-three patients were included into three protocol groups: Group I, 300 mgI/mL 120 kVp; Group II, 400 mgI/mL 120 kVp; Group III, 400 mgI/mL 90 kVp. Hounsfield... (More)
Background:

Computed tomography angiography (CTA) of intracranial arteries has high demands on image quality. Important parameters influencing vessel enhancement are injection rate, concentration of contrast media and tube voltage.



Purpose:

To evaluate the impact of an increase of contrast media concentration from 300 to 400 mg iodine/mL (mgI/mL) and the effect of a decrease of tube voltage from 120 to 90 kVp on vessel attenuation and image quality in CT angiography of intracranial arteries.



Material and Methods

Sixty-three patients were included into three protocol groups: Group I, 300 mgI/mL 120 kVp; Group II, 400 mgI/mL 120 kVp; Group III, 400 mgI/mL 90 kVp. Hounsfield units (HU) were measured in the internal carotid artery (ICA) and the M1 and M2 segments of the middle cerebral artery. Image quality grading was performed regarding M1 and M2 segments, volume rendering and general image impression.



Results:

The difference in mean HU in ICA concerning the effect of contrast media concentration was statistically significant (P = 0.03) in favor of higher concentration. The difference in ICA enhancement due to the effect of tube voltage was statistically significant (P < 0.01) in favor of lower tube voltage. The increase of contrast medium concentration raised the mean enhancement in ICA with 18% and the decrease of tube voltage raised the mean enhancement with 37%. Image quality grading showed a trend towards improved grading for higher contrast concentration and lower tube voltage. Statistically significant better grading was found for the combined effect of both measures except for general impression (P 0.01-0.05).



Conclusion:

The uses of highly concentrated contrast media and low tube voltage are easily performed measures to improve image quality in CTA of intracranial vessel. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta radiologica (Stockholm, Sweden : 1987)
volume
53
issue
8
pages
929 - 934
publisher
John Wiley & Sons
external identifiers
  • WOS:000310820000016
  • PMID:22903017
  • Scopus:84867704575
ISSN
1600-0455
DOI
10.1258/ar.2012.120218
language
English
LU publication?
yes
id
ffcb8e9a-ecbb-4a41-bcc7-99d20d6c5a27 (old id 3047393)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22903017?dopt=Abstract
date added to LUP
2012-09-05 20:03:40
date last changed
2016-10-30 04:35:56
@misc{ffcb8e9a-ecbb-4a41-bcc7-99d20d6c5a27,
  abstract     = {Background:<br/><br>
Computed tomography angiography (CTA) of intracranial arteries has high demands on image quality. Important parameters influencing vessel enhancement are injection rate, concentration of contrast media and tube voltage.<br/><br>
<br/><br>
Purpose:<br/><br>
To evaluate the impact of an increase of contrast media concentration from 300 to 400 mg iodine/mL (mgI/mL) and the effect of a decrease of tube voltage from 120 to 90 kVp on vessel attenuation and image quality in CT angiography of intracranial arteries.<br/><br>
<br/><br>
Material and Methods<br/><br>
Sixty-three patients were included into three protocol groups: Group I, 300 mgI/mL 120 kVp; Group II, 400 mgI/mL 120 kVp; Group III, 400 mgI/mL 90 kVp. Hounsfield units (HU) were measured in the internal carotid artery (ICA) and the M1 and M2 segments of the middle cerebral artery. Image quality grading was performed regarding M1 and M2 segments, volume rendering and general image impression.<br/><br>
<br/><br>
Results:<br/><br>
The difference in mean HU in ICA concerning the effect of contrast media concentration was statistically significant (P = 0.03) in favor of higher concentration. The difference in ICA enhancement due to the effect of tube voltage was statistically significant (P &lt; 0.01) in favor of lower tube voltage. The increase of contrast medium concentration raised the mean enhancement in ICA with 18% and the decrease of tube voltage raised the mean enhancement with 37%. Image quality grading showed a trend towards improved grading for higher contrast concentration and lower tube voltage. Statistically significant better grading was found for the combined effect of both measures except for general impression (P 0.01-0.05).<br/><br>
<br/><br>
Conclusion:<br/><br>
The uses of highly concentrated contrast media and low tube voltage are easily performed measures to improve image quality in CTA of intracranial vessel.},
  author       = {Ramgren, Birgitta and Björkman-Burtscher, Isabella and Holtås, Stig and Siemund, Roger},
  issn         = {1600-0455},
  language     = {eng},
  number       = {8},
  pages        = {929--934},
  publisher    = {ARRAY(0xa00ec28)},
  series       = {Acta radiologica (Stockholm, Sweden : 1987)},
  title        = {CT angiography of intracranial arterial vessels: impact of tube voltage and contrast media concentration on image quality.},
  url          = {http://dx.doi.org/10.1258/ar.2012.120218},
  volume       = {53},
  year         = {2012},
}