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Polymeric micro-channel-based functionalisation system for micro-cantilevers

Tenje, Maria LU ; Calleja, Montserrat and Boisen, Anja (2005) In Ultramicroscopy 105(1). p.281-286
Abstract
A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing... (More)
A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing each cantilever individually to obtain an array functionalised with different probe molecules. Using this micro-channel system in combination with a cantilever array establishes a method of detecting multiple target molecules simultaneously. Fluorescence experiments have been performed to show the working principle of the micro-channel system in combination with a cantilever array. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
subject
in
Ultramicroscopy
volume
105
issue
1
pages
281 - 286
publisher
Elsevier
external identifiers
  • Scopus:27544464686
ISSN
0304-3991
DOI
10.1016/j.ultramic.2005.06.053
language
English
LU publication?
no
id
8dfbd40a-51c6-4319-8282-407da002c929 (old id 3157986)
date added to LUP
2012-10-25 17:19:47
date last changed
2016-10-13 04:24:27
@misc{8dfbd40a-51c6-4319-8282-407da002c929,
  abstract     = {A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing each cantilever individually to obtain an array functionalised with different probe molecules. Using this micro-channel system in combination with a cantilever array establishes a method of detecting multiple target molecules simultaneously. Fluorescence experiments have been performed to show the working principle of the micro-channel system in combination with a cantilever array.},
  author       = {Tenje, Maria and Calleja, Montserrat and Boisen, Anja},
  issn         = {0304-3991},
  language     = {eng},
  number       = {1},
  pages        = {281--286},
  publisher    = {ARRAY(0x773ec18)},
  series       = {Ultramicroscopy},
  title        = {Polymeric micro-channel-based functionalisation system for micro-cantilevers},
  url          = {http://dx.doi.org/10.1016/j.ultramic.2005.06.053},
  volume       = {105},
  year         = {2005},
}