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Polymeric micro-channel-based functionalisation system for micro-cantilevers

Nordström, Maria LU ; Calleja, Montserrat and Boisen, Anja (2005) In Ultramicroscopy 105(1). p.281-286
Abstract
A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing... (More)
A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing each cantilever individually to obtain an array functionalised with different probe molecules. Using this micro-channel system in combination with a cantilever array establishes a method of detecting multiple target molecules simultaneously. Fluorescence experiments have been performed to show the working principle of the micro-channel system in combination with a cantilever array. (Less)
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author
; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Ultramicroscopy
volume
105
issue
1
pages
281 - 286
publisher
Elsevier
external identifiers
  • scopus:27544464686
ISSN
0304-3991
DOI
10.1016/j.ultramic.2005.06.053
language
English
LU publication?
no
id
8dfbd40a-51c6-4319-8282-407da002c929 (old id 3157986)
date added to LUP
2016-04-04 09:07:49
date last changed
2022-04-23 19:08:56
@article{8dfbd40a-51c6-4319-8282-407da002c929,
  abstract     = {{A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing each cantilever individually to obtain an array functionalised with different probe molecules. Using this micro-channel system in combination with a cantilever array establishes a method of detecting multiple target molecules simultaneously. Fluorescence experiments have been performed to show the working principle of the micro-channel system in combination with a cantilever array.}},
  author       = {{Nordström, Maria and Calleja, Montserrat and Boisen, Anja}},
  issn         = {{0304-3991}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{281--286}},
  publisher    = {{Elsevier}},
  series       = {{Ultramicroscopy}},
  title        = {{Polymeric micro-channel-based functionalisation system for micro-cantilevers}},
  url          = {{http://dx.doi.org/10.1016/j.ultramic.2005.06.053}},
  doi          = {{10.1016/j.ultramic.2005.06.053}},
  volume       = {{105}},
  year         = {{2005}},
}