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Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat

Dahlbäck, Björn LU ; Hansson, C.; Islam, M. Q.; Szpirer, J.; Szpirer, C.; Lundwall, Åke LU and Levan, G. (1988) In Somat Cell Mol Genet 14(5). p.14-509
Abstract
Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.
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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
DNA Probes, Molecular, Cloning, Pair 1, Human, *Chromosomes, *Chromosome Mapping, Animals, Southern, Blotting, Factor V/*genetics, Humans, Hybrid Cells, Nucleic Acid Hybridization, Rats, Research Support, Non-U.S. Gov't
in
Somat Cell Mol Genet
volume
14
issue
5
pages
14 - 509
external identifiers
  • Scopus:0023764379
language
English
LU publication?
yes
id
a85d319f-ea9b-4f6f-94c3-fd85955e2c2a (old id 3965159)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3175767
date added to LUP
2013-08-11 15:13:26
date last changed
2016-10-13 04:57:15
@misc{a85d319f-ea9b-4f6f-94c3-fd85955e2c2a,
  abstract     = {Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.},
  author       = {Dahlbäck, Björn and Hansson, C. and Islam, M. Q. and Szpirer, J. and Szpirer, C. and Lundwall, Åke and Levan, G.},
  keyword      = {DNA Probes,Molecular,Cloning,Pair 1,Human,*Chromosomes,*Chromosome Mapping,Animals,Southern,Blotting,Factor V/*genetics,Humans,Hybrid Cells,Nucleic Acid Hybridization,Rats,Research Support,Non-U.S. Gov't},
  language     = {eng},
  number       = {5},
  pages        = {14--509},
  series       = {Somat Cell Mol Genet},
  title        = {Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat},
  volume       = {14},
  year         = {1988},
}