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Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat

Dahlbäck, Björn LU ; Hansson, C. ; Islam, M. Q. ; Szpirer, J. ; Szpirer, C. ; Lundwall, Åke LU and Levan, G. (1988) In Somatic Cell and Molecular Genetics 14(5). p.14-509
Abstract
Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
DNA Probes, Molecular, Cloning, Pair 1, Human, *Chromosomes, *Chromosome Mapping, Animals, Southern, Blotting, Factor V/*genetics, Humans, Hybrid Cells, Nucleic Acid Hybridization, Rats, Research Support, Non-U.S. Gov't
in
Somatic Cell and Molecular Genetics
volume
14
issue
5
pages
14 - 509
publisher
Springer
external identifiers
  • scopus:0023764379
ISSN
0740-7750
language
English
LU publication?
yes
additional info
5
id
a85d319f-ea9b-4f6f-94c3-fd85955e2c2a (old id 3965159)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3175767
date added to LUP
2016-04-04 13:44:14
date last changed
2022-08-29 11:43:48
@article{a85d319f-ea9b-4f6f-94c3-fd85955e2c2a,
  abstract     = {{Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.}},
  author       = {{Dahlbäck, Björn and Hansson, C. and Islam, M. Q. and Szpirer, J. and Szpirer, C. and Lundwall, Åke and Levan, G.}},
  issn         = {{0740-7750}},
  keywords     = {{DNA Probes; Molecular; Cloning; Pair 1; Human; *Chromosomes; *Chromosome Mapping; Animals; Southern; Blotting; Factor V/*genetics; Humans; Hybrid Cells; Nucleic Acid Hybridization; Rats; Research Support; Non-U.S. Gov't}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{14--509}},
  publisher    = {{Springer}},
  series       = {{Somatic Cell and Molecular Genetics}},
  title        = {{Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat}},
  url          = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3175767}},
  volume       = {{14}},
  year         = {{1988}},
}