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Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates

Ulvsbäck, M.; Spurr, N. K. and Lundwall, Åke LU (1991) In Genomics 11(4). p.4-920
Abstract
The gene for beta-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10. The coding nucleotides of the human gene are separated into four exons by relatively large introns. A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency.
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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
*Prostatic Secretory Proteins, Molecular Sequence Data, Humans, Dna, Molecular, Cloning, Pair 10, Human, *Chromosomes, Chromosome Mapping, Southern, Blotting, Animals, Base Sequence, Proteins/*genetics, Research Support, Non-U.S. Gov't, Restriction Mapping, Semen/*metabolism, Seminal Plasma Proteins, Vertebrates/genetics
in
Genomics
volume
11
issue
4
pages
4 - 920
publisher
Academic Press
external identifiers
  • Scopus:0026353104
ISSN
1089-8646
language
English
LU publication?
yes
id
b73e2116-6113-4890-a2ce-0aa61c8837c8 (old id 3965204)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1783399
date added to LUP
2013-08-11 15:11:42
date last changed
2016-10-13 05:03:11
@misc{b73e2116-6113-4890-a2ce-0aa61c8837c8,
  abstract     = {The gene for beta-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10. The coding nucleotides of the human gene are separated into four exons by relatively large introns. A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency.},
  author       = {Ulvsbäck, M. and Spurr, N. K. and Lundwall, Åke},
  issn         = {1089-8646},
  keyword      = {*Prostatic Secretory Proteins,Molecular Sequence Data,Humans,Dna,Molecular,Cloning,Pair 10,Human,*Chromosomes,Chromosome Mapping,Southern,Blotting,Animals,Base Sequence,Proteins/*genetics,Research Support,Non-U.S. Gov't,Restriction Mapping,Semen/*metabolism,Seminal Plasma Proteins,Vertebrates/genetics},
  language     = {eng},
  number       = {4},
  pages        = {4--920},
  publisher    = {ARRAY(0x91dd708)},
  series       = {Genomics},
  title        = {Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates},
  volume       = {11},
  year         = {1991},
}