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Inflammatory Cytokines and Biomarkers of Cartilage Metabolism 8 Years After Anterior Cruciate Ligament Reconstruction: Results From Operated and Contralateral Knees.

Åhlén, Martina; Roshani, Leyla; Lidén, Mattias; Struglics, André LU ; Rostgård-Christensen, Lars and Kartus, Jüri (2015) In American Journal of Sports Medicine
Abstract
Patients who sustain an acute anterior cruciate ligament (ACL) rupture are at increased risk to develop posttraumatic arthritis (PTA) in the injured knee whether the ACL is reconstructed or treated nonoperatively. Inflammatory cytokines and cartilage degradation biomarkers are elevated at the time of acute injury and postoperatively. This suggests that one mechanism for PTA may be an inflammatory degradative process initiated on the acute injury and sustained for some length of time independent of whether adequate joint stability is restored.
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author
organization
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type
Contribution to journal
publication status
published
subject
in
American Journal of Sports Medicine
publisher
American Orthopaedic Society for Sports Medicine
external identifiers
  • PMID:25787698
  • Scopus:84930532671
ISSN
1552-3365
DOI
10.1177/0363546515574059
language
English
LU publication?
yes
id
aa19d62e-9ecd-4c34-abe4-d5dcdf21b048 (old id 5258138)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25787698?dopt=Abstract
date added to LUP
2015-04-05 14:49:43
date last changed
2016-11-01 10:18:14
@misc{aa19d62e-9ecd-4c34-abe4-d5dcdf21b048,
  abstract     = {Patients who sustain an acute anterior cruciate ligament (ACL) rupture are at increased risk to develop posttraumatic arthritis (PTA) in the injured knee whether the ACL is reconstructed or treated nonoperatively. Inflammatory cytokines and cartilage degradation biomarkers are elevated at the time of acute injury and postoperatively. This suggests that one mechanism for PTA may be an inflammatory degradative process initiated on the acute injury and sustained for some length of time independent of whether adequate joint stability is restored.},
  author       = {Åhlén, Martina and Roshani, Leyla and Lidén, Mattias and Struglics, André and Rostgård-Christensen, Lars and Kartus, Jüri},
  issn         = {1552-3365},
  language     = {eng},
  month        = {03},
  publisher    = {ARRAY(0x8f67af0)},
  series       = {American Journal of Sports Medicine},
  title        = {Inflammatory Cytokines and Biomarkers of Cartilage Metabolism 8 Years After Anterior Cruciate Ligament Reconstruction: Results From Operated and Contralateral Knees.},
  url          = {http://dx.doi.org/10.1177/0363546515574059},
  year         = {2015},
}