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An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments

Åkesson, Mats ; Hagander, Per LU and Axelsson, Jan Peter (2002) 8th IFAC International Conference on Computer Applications in Biotechnology (CAB8) p.213-218
Abstract
A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Fermentation process, probing, extremum control, process control
host publication
Computer Applications in Biotechnology 2001
pages
213 - 218
publisher
Elsevier
conference name
8th IFAC International Conference on Computer Applications in Biotechnology (CAB8)
conference location
Quebeq City, Canada
conference dates
2001-06-24 - 2001-06-27
external identifiers
  • wos:000177564700037
ISBN
0080436811
language
English
LU publication?
yes
id
4edaf96b-3832-485f-9cec-60f80a23645c (old id 537890)
date added to LUP
2016-04-04 11:08:28
date last changed
2019-12-11 09:36:39
@inproceedings{4edaf96b-3832-485f-9cec-60f80a23645c,
  abstract     = {{A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.}},
  author       = {{Åkesson, Mats and Hagander, Per and Axelsson, Jan Peter}},
  booktitle    = {{Computer Applications in Biotechnology 2001}},
  isbn         = {{0080436811}},
  keywords     = {{Fermentation process; probing; extremum control; process control}},
  language     = {{eng}},
  pages        = {{213--218}},
  publisher    = {{Elsevier}},
  title        = {{An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments}},
  year         = {{2002}},
}