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Neuropsychological tests as discriminators between dementia of Alzheimer type and frontotemporal dementia

Elfgren, C. LU ; Brun, A. LU ; Gustafson, L. LU ; Johanson, A. LU ; Minthon, L. LU ; Passant, U. LU and Risberg, J. LU (1994) In International Journal of Geriatric Psychiatry 9(8). p.635-642
Abstract
The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memory. Eighty-nine per cent of the sample was correctly classified by discriminant analysis. Evaluating the ability of the obtained discriminant function to differentiate between groups of DAT and FTD in a new, clinically diagnosed sample of 38 cases yielded an overall success rate of 84%. The results suggest that cognitive tests may be helpful for... (More)
The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memory. Eighty-nine per cent of the sample was correctly classified by discriminant analysis. Evaluating the ability of the obtained discriminant function to differentiate between groups of DAT and FTD in a new, clinically diagnosed sample of 38 cases yielded an overall success rate of 84%. The results suggest that cognitive tests may be helpful for differential diagnosis in the context of a neuropsychiatric examination. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
keywords
adult, aged, Alzheimer disease, article, autopsy, clinical article, clinical trial, cognition, dementia, depth perception, differential diagnosis, discriminant analysis, female, frontal lobe, human, male, neuropsychological test, task performance, verbal behavior, verbal memory
in
International Journal of Geriatric Psychiatry
volume
9
issue
8
pages
635 - 642
external identifiers
  • Scopus:0028027363
ISSN
1099-1166
DOI
10.1002/gps.930090807
language
English
LU publication?
no
id
7a12b863-c164-42d9-8bb6-7426e08e844a
date added to LUP
2016-10-29 14:43:54
date last changed
2016-11-27 04:43:46
@misc{7a12b863-c164-42d9-8bb6-7426e08e844a,
  abstract     = {The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memory. Eighty-nine per cent of the sample was correctly classified by discriminant analysis. Evaluating the ability of the obtained discriminant function to differentiate between groups of DAT and FTD in a new, clinically diagnosed sample of 38 cases yielded an overall success rate of 84%. The results suggest that cognitive tests may be helpful for differential diagnosis in the context of a neuropsychiatric examination.},
  author       = {Elfgren, C. and Brun, A. and Gustafson, L. and Johanson, A. and Minthon, L. and Passant, U. and Risberg, J.},
  issn         = {1099-1166},
  keyword      = {adult,aged,Alzheimer disease,article,autopsy,clinical article,clinical trial,cognition,dementia,depth perception,differential diagnosis,discriminant analysis,female,frontal lobe,human,male,neuropsychological test,task performance,verbal behavior,verbal memory},
  language     = {eng},
  month        = {10},
  number       = {8},
  pages        = {635--642},
  series       = {International Journal of Geriatric Psychiatry},
  title        = {Neuropsychological tests as discriminators between dementia of Alzheimer type and frontotemporal dementia},
  url          = {http://dx.doi.org/10.1002/gps.930090807},
  volume       = {9},
  year         = {1994},
}