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Convection-dominated dispersion regime in wide-bore chromatography : A transport-based approach to assess the occurrence of slip flows in microchannels

Adrover, Alessandra; Cerbelli, Stefano; Garofalo, Fabio LU and Giona, Massimiliano (2009) In Analytical Chemistry 81(19). p.8009-8014
Abstract

This article develops the theoretical analysis of transport and dispersion phenomena in wide-bore chromatography at values of the Peclet number Pe beyond the upper bound of validity of the Taylor-Aris theory. It is shown that for Poiseuille flows in cylindrical capillaries the average residence time grows logarithmically with the Peclet number, while the variance of the outlet chromatogram scales as the power 1/3 of Pe. In the presence of slip boundary conditions, both the mean and the variance of the outlet chromatograms saturate at high Pe, and this phenomenon provides an indirect transport-based way to detect slip flow conditions at the solid walls and, more generally, flow distributions in channel flows. © 2009 American Chemical... (More)

This article develops the theoretical analysis of transport and dispersion phenomena in wide-bore chromatography at values of the Peclet number Pe beyond the upper bound of validity of the Taylor-Aris theory. It is shown that for Poiseuille flows in cylindrical capillaries the average residence time grows logarithmically with the Peclet number, while the variance of the outlet chromatogram scales as the power 1/3 of Pe. In the presence of slip boundary conditions, both the mean and the variance of the outlet chromatograms saturate at high Pe, and this phenomenon provides an indirect transport-based way to detect slip flow conditions at the solid walls and, more generally, flow distributions in channel flows. © 2009 American Chemical Society.

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author
publishing date
type
Contribution to journal
publication status
published
in
Analytical Chemistry
volume
81
issue
19
pages
6 pages
publisher
The American Chemical Society
external identifiers
  • Scopus:70349629996
ISSN
0003-2700
DOI
10.1021/ac901504u
language
English
LU publication?
no
id
7cf0cd10-5a3c-460f-9840-beef2cfb09c6
date added to LUP
2016-06-27 10:09:46
date last changed
2016-09-20 03:07:23
@misc{7cf0cd10-5a3c-460f-9840-beef2cfb09c6,
  abstract     = {<p>This article develops the theoretical analysis of transport and dispersion phenomena in wide-bore chromatography at values of the Peclet number Pe beyond the upper bound of validity of the Taylor-Aris theory. It is shown that for Poiseuille flows in cylindrical capillaries the average residence time grows logarithmically with the Peclet number, while the variance of the outlet chromatogram scales as the power 1/3 of Pe. In the presence of slip boundary conditions, both the mean and the variance of the outlet chromatograms saturate at high Pe, and this phenomenon provides an indirect transport-based way to detect slip flow conditions at the solid walls and, more generally, flow distributions in channel flows. © 2009 American Chemical Society.</p>},
  author       = {Adrover, Alessandra and Cerbelli, Stefano and Garofalo, Fabio and Giona, Massimiliano},
  issn         = {0003-2700},
  language     = {eng},
  month        = {10},
  number       = {19},
  pages        = {8009--8014},
  publisher    = {ARRAY(0x8b47ed0)},
  series       = {Analytical Chemistry},
  title        = {Convection-dominated dispersion regime in wide-bore chromatography : A transport-based approach to assess the occurrence of slip flows in microchannels},
  url          = {http://dx.doi.org/10.1021/ac901504u},
  volume       = {81},
  year         = {2009},
}