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Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.

Tada, Hayato; Melander, Olle LU ; Louie, Judy Z; Catanese, Joseph J; Rowland, Charles M; Devlin, James J; Kathiresan, Sekar and Shiffman, Dov (2015) In European Heart Journal
Abstract
Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Heart Journal
publisher
Oxford University Press
external identifiers
  • PMID:26392438
  • WOS:000371250400012
  • Scopus:84962173287
ISSN
1522-9645
DOI
10.1093/eurheartj/ehv462
language
English
LU publication?
yes
id
0a361e7e-7b52-4392-a1fe-0cc3478cf29d (old id 8035423)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26392438?dopt=Abstract
date added to LUP
2015-10-03 17:26:11
date last changed
2016-11-06 04:26:19
@misc{0a361e7e-7b52-4392-a1fe-0cc3478cf29d,
  abstract     = {Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.},
  author       = {Tada, Hayato and Melander, Olle and Louie, Judy Z and Catanese, Joseph J and Rowland, Charles M and Devlin, James J and Kathiresan, Sekar and Shiffman, Dov},
  issn         = {1522-9645},
  language     = {eng},
  month        = {09},
  publisher    = {ARRAY(0xc0f1a48)},
  series       = {European Heart Journal},
  title        = {Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.},
  url          = {http://dx.doi.org/10.1093/eurheartj/ehv462},
  year         = {2015},
}