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Adiposity in children born small for gestational age is associated with β-cell function, genetic variants for insulin resistance and response to growth hormone treatment.

Thankamony, Ajay; Jensen, Rikke Beck; O'Connell, Susan M; Day, Felix; Kirk, Jeremy; Donaldson, Malcolm; Ivarsson, Sten LU ; Söder, Olle; Roche, Edna and Hoey, Hilary, et al. (2015) In The Journal of clinical endocrinology and metabolism p.20153019-20153019
Abstract
Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to Growth Hormone (GH). We aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to GH treatment in short children born small for gestational age (SGA).
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Contribution to journal
publication status
published
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in
The Journal of clinical endocrinology and metabolism
issue
nov 20
pages
20153019 - 20153019
publisher
The Endocrine Society
external identifiers
  • PMID:26588449
  • Scopus:84954480886
ISSN
1945-7197
DOI
10.1210/jc.2015-3019
language
English
LU publication?
yes
id
3cf0571d-f23f-43f2-9a01-528f73a45fb6 (old id 8235031)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26588449?dopt=Abstract
date added to LUP
2015-12-06 00:33:47
date last changed
2016-11-09 14:39:54
@misc{3cf0571d-f23f-43f2-9a01-528f73a45fb6,
  abstract     = {Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to Growth Hormone (GH). We aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to GH treatment in short children born small for gestational age (SGA).},
  author       = {Thankamony, Ajay and Jensen, Rikke Beck and O'Connell, Susan M and Day, Felix and Kirk, Jeremy and Donaldson, Malcolm and Ivarsson, Sten and Söder, Olle and Roche, Edna and Hoey, Hilary and Ong, Ken K and Dunger, David B and Juul, Anders},
  issn         = {1945-7197},
  language     = {eng},
  number       = {nov 20},
  pages        = {20153019--20153019},
  publisher    = {ARRAY(0xb8196c0)},
  series       = {The Journal of clinical endocrinology and metabolism},
  title        = {Adiposity in children born small for gestational age is associated with β-cell function, genetic variants for insulin resistance and response to growth hormone treatment.},
  url          = {http://dx.doi.org/10.1210/jc.2015-3019},
  year         = {2015},
}