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Two meals with different carbohydrate, fat and protein contents render equivalent postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin

Ohlsson, Bodil LU ; Darwiche, Gassan LU ; Roth, Bodil LU and Höglund, Peter LU (2016) In International Journal of Food Sciences and Nutrition 67(7). p.872-880
Abstract

The aim was to compare postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin between a control breakfast and a moderately low-carbohydrate test breakfast, given randomly after 10-h fast. Blood samples were collected before and repeatedly after the meal. Plasma calprotectin, cortisol, triglycerides and zonulin were analyzed. The total area under the curve (tAUC) and change in AUC from baseline (dAUC) were calculated. Ratios between the test and control values were calculated to investigate equivalence. Healthy volunteers (8 men and 12 women; 46.0 ± 14.5 years) were included. tAUCs of cortisol and triglycerides did not differ between the breakfasts (p = 0.158 versus p = 0.579). Cortisol dAUCs were decreased and... (More)

The aim was to compare postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin between a control breakfast and a moderately low-carbohydrate test breakfast, given randomly after 10-h fast. Blood samples were collected before and repeatedly after the meal. Plasma calprotectin, cortisol, triglycerides and zonulin were analyzed. The total area under the curve (tAUC) and change in AUC from baseline (dAUC) were calculated. Ratios between the test and control values were calculated to investigate equivalence. Healthy volunteers (8 men and 12 women; 46.0 ± 14.5 years) were included. tAUCs of cortisol and triglycerides did not differ between the breakfasts (p = 0.158 versus p = 0.579). Cortisol dAUCs were decreased and triglyceride dAUCs were increased after both breakfasts, with no differences between the breakfasts (p = 0.933 versus p = 0.277). Calprotectin and zonulin levels were unaffected. The meals were bioequivalent for cortisol, triglycerides and zonulin, but not for calprotectin.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
calprotectin, cortisol, high-fat content, high-protein content, low-carbohydrate content, triglycerides, zonulin
in
International Journal of Food Sciences and Nutrition
volume
67
issue
7
pages
9 pages
publisher
Taylor & Francis
external identifiers
  • Scopus:84976346985
ISSN
0963-7486
DOI
10.1080/09637486.2016.1202214
language
English
LU publication?
yes
id
b6ce3358-b4da-41c3-8c41-2a11ac04e361
date added to LUP
2016-07-18 09:31:58
date last changed
2016-10-25 14:35:20
@misc{b6ce3358-b4da-41c3-8c41-2a11ac04e361,
  abstract     = {<p>The aim was to compare postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin between a control breakfast and a moderately low-carbohydrate test breakfast, given randomly after 10-h fast. Blood samples were collected before and repeatedly after the meal. Plasma calprotectin, cortisol, triglycerides and zonulin were analyzed. The total area under the curve (tAUC) and change in AUC from baseline (dAUC) were calculated. Ratios between the test and control values were calculated to investigate equivalence. Healthy volunteers (8 men and 12 women; 46.0 ± 14.5 years) were included. tAUCs of cortisol and triglycerides did not differ between the breakfasts (p = 0.158 versus p = 0.579). Cortisol dAUCs were decreased and triglyceride dAUCs were increased after both breakfasts, with no differences between the breakfasts (p = 0.933 versus p = 0.277). Calprotectin and zonulin levels were unaffected. The meals were bioequivalent for cortisol, triglycerides and zonulin, but not for calprotectin.</p>},
  author       = {Ohlsson, Bodil and Darwiche, Gassan and Roth, Bodil and Höglund, Peter},
  issn         = {0963-7486},
  keyword      = {calprotectin,cortisol,high-fat content,high-protein content,low-carbohydrate content,triglycerides,zonulin},
  language     = {eng},
  month        = {06},
  number       = {7},
  pages        = {872--880},
  publisher    = {ARRAY(0x9d75bd8)},
  series       = {International Journal of Food Sciences and Nutrition},
  title        = {Two meals with different carbohydrate, fat and protein contents render equivalent postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin},
  url          = {http://dx.doi.org/10.1080/09637486.2016.1202214},
  volume       = {67},
  year         = {2016},
}