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A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens

Hellberg, Åsa LU ; Pesjak, Emma; Karlsson, Jessica and Storry, Jill R. LU (2016) In Transfusion 56(9). p.2391-2392
Abstract

We report a novel RHCE*02 allele in a Swedish blood donor that is characterized by the change c.460A>G (Arg154Gly). The blood donor's red blood cells showed variable reactivity with different monoclonal anti-C and anti-e and antigen strength was markedly weakened. We believe that these changes represent both a quantitative and qualitative alteration of the antigens encoded by this allele.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Transfusion
volume
56
issue
9
pages
2 pages
publisher
Wiley-Blackwell
external identifiers
  • Scopus:84987621248
ISSN
0041-1132
DOI
10.1111/trf.13679
language
English
LU publication?
yes
id
bc1a67f2-713e-4b9d-a1ed-3373330ef67a
date added to LUP
2016-10-06 09:09:19
date last changed
2016-10-06 09:09:19
@misc{bc1a67f2-713e-4b9d-a1ed-3373330ef67a,
  abstract     = {<p>We report a novel RHCE*02 allele in a Swedish blood donor that is characterized by the change c.460A&gt;G (Arg154Gly). The blood donor's red blood cells showed variable reactivity with different monoclonal anti-C and anti-e and antigen strength was markedly weakened. We believe that these changes represent both a quantitative and qualitative alteration of the antigens encoded by this allele.</p>},
  author       = {Hellberg, Åsa and Pesjak, Emma and Karlsson, Jessica and Storry, Jill R.},
  issn         = {0041-1132},
  language     = {eng},
  month        = {09},
  number       = {9},
  pages        = {2391--2392},
  publisher    = {ARRAY(0x96231e0)},
  series       = {Transfusion},
  title        = {A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens},
  url          = {http://dx.doi.org/10.1111/trf.13679},
  volume       = {56},
  year         = {2016},
}