Spermidine/spermine-N1-acetyltransferase activity in isoprenaline-stimulated rat salivary glands
Ekström, J. ; Månsson, B ; Nilsson, B O LU
; Rosengren, Elsa
and Tobin, G
(1989)
In Acta Physiologica Scandinavica
135(3).
p.54-249
- Abstract
In parotid, sublingual and submaxillary glands stimulated by continuous intravenous infusion of isoprenaline at various doses for 3 h, the concentrations of the polyamines putrescine, spermidine, spermine and N1-acetylspermidine as well as the activities of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase were determined. Ornithine decarboxylase is the enzyme that catalyses the formation of putrescine from ornithine. The most striking effect was observed in parotid glands. Here, the beta-adrenergic agonist increased the activity of spermidine/spermine-N1-acetyltransferase markedly, but only slightly (if at all) that of ornithine decarboxylase. It also increased the concentrations of N1-acetylspermidine and putrescine... (More)
In parotid, sublingual and submaxillary glands stimulated by continuous intravenous infusion of isoprenaline at various doses for 3 h, the concentrations of the polyamines putrescine, spermidine, spermine and N1-acetylspermidine as well as the activities of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase were determined. Ornithine decarboxylase is the enzyme that catalyses the formation of putrescine from ornithine. The most striking effect was observed in parotid glands. Here, the beta-adrenergic agonist increased the activity of spermidine/spermine-N1-acetyltransferase markedly, but only slightly (if at all) that of ornithine decarboxylase. It also increased the concentrations of N1-acetylspermidine and putrescine markedly. The result obtained in this gland indicates interconversion of higher polyamines to putrescine.
(Less)
- author
- Ekström, J.
; Månsson, B
; Nilsson, B O
LU
; Rosengren, Elsa
and Tobin, G
- organization
- publishing date
- 1989-03
- type
- Contribution to journal
- publication status
- published
- keywords
- Acetyltransferases, Animals, Infusions, Intravenous, Isoproterenol, Male, Organ Size, Ornithine Decarboxylase, Putrescine, Rats, Rats, Inbred Strains, Salivary Glands, Spermidine, Spermine
- in
- Acta Physiologica Scandinavica
- volume
- 135
- issue
- 3
- pages
- 6 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:2929364
- scopus:0024477714
- ISSN
- 0001-6772
- DOI
- 10.1111/j.1748-1716.1989.tb08574.x
- language
- English
- LU publication?
- yes
- id
- d8303fc6-8afe-4377-aded-5863fbd4e315
- date added to LUP
- 2016-06-17 16:51:05
- date last changed
- 2024-01-04 08:29:28
@article{d8303fc6-8afe-4377-aded-5863fbd4e315,
abstract = {{<p>In parotid, sublingual and submaxillary glands stimulated by continuous intravenous infusion of isoprenaline at various doses for 3 h, the concentrations of the polyamines putrescine, spermidine, spermine and N1-acetylspermidine as well as the activities of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase were determined. Ornithine decarboxylase is the enzyme that catalyses the formation of putrescine from ornithine. The most striking effect was observed in parotid glands. Here, the beta-adrenergic agonist increased the activity of spermidine/spermine-N1-acetyltransferase markedly, but only slightly (if at all) that of ornithine decarboxylase. It also increased the concentrations of N1-acetylspermidine and putrescine markedly. The result obtained in this gland indicates interconversion of higher polyamines to putrescine.</p>}},
author = {{Ekström, J. and Månsson, B and Nilsson, B O and Rosengren, Elsa and Tobin, G}},
issn = {{0001-6772}},
keywords = {{Acetyltransferases; Animals; Infusions, Intravenous; Isoproterenol; Male; Organ Size; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Salivary Glands; Spermidine; Spermine}},
language = {{eng}},
number = {{3}},
pages = {{54--249}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Physiologica Scandinavica}},
title = {{Spermidine/spermine-N1-acetyltransferase activity in isoprenaline-stimulated rat salivary glands}},
url = {{http://dx.doi.org/10.1111/j.1748-1716.1989.tb08574.x}},
doi = {{10.1111/j.1748-1716.1989.tb08574.x}},
volume = {{135}},
year = {{1989}},
}