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How do carriers of hemophilia and their spouses experience prenatal diagnosis by chorionic villus sampling?

Tedgård, Ulf LU ; Ljung, R. LU and McNeil, T. F. LU (1999) In Clinical Genetics 55(1). p.26-33
Abstract

A semistructured personal interview with 29 female carriers of hemophilia and 23 of their spouses was performed at a median of 3 1/2 years after the first chorionic villus sampling (CVS) and gene analysis. Carriers with a hemophilic father or brother, had high sense of coherence (SOC) scores, and thus would be expected to have good ability to handle the stress of prenatal diagnosis (PD). Prenatal diagnosis of hemophilia by CVS was generally well accepted by the women and their spouses. However, the period while waiting for test results was experienced as emotionally troublesome by both the women and their spouses; women reporting significantly more psychiatric or psychosomatic symptoms than men. Positive effects resulting from... (More)

A semistructured personal interview with 29 female carriers of hemophilia and 23 of their spouses was performed at a median of 3 1/2 years after the first chorionic villus sampling (CVS) and gene analysis. Carriers with a hemophilic father or brother, had high sense of coherence (SOC) scores, and thus would be expected to have good ability to handle the stress of prenatal diagnosis (PD). Prenatal diagnosis of hemophilia by CVS was generally well accepted by the women and their spouses. However, the period while waiting for test results was experienced as emotionally troublesome by both the women and their spouses; women reporting significantly more psychiatric or psychosomatic symptoms than men. Positive effects resulting from participation by the spouse on how the women experienced PD could not be identified. Selective abortion after first trimester PD was clearly experienced as emotionally painful by both the women and their spouses, these reactions being similar to, but not as pronounced as those found after second trimester selective abortion. Notably, signs of depressive mood were observed several years after the abortion, and the provision of psychosocial support should be recommended for couples who decide upon termination of pregnancy following PD.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Chorionic villus sampling, Hemophilia, Prenatal diagnosis, Psychology, Sense of coherence, Spouse
in
Clinical Genetics
volume
55
issue
1
pages
8 pages
publisher
Wiley-Blackwell
external identifiers
  • Scopus:0344450767
ISSN
0009-9163
language
English
LU publication?
yes
id
da0783fc-7666-483a-9a8f-e492300dfe53
date added to LUP
2016-11-08 14:56:00
date last changed
2016-11-18 13:45:34
@misc{da0783fc-7666-483a-9a8f-e492300dfe53,
  abstract     = {<p>A semistructured personal interview with 29 female carriers of hemophilia and 23 of their spouses was performed at a median of 3 1/2 years after the first chorionic villus sampling (CVS) and gene analysis. Carriers with a hemophilic father or brother, had high sense of coherence (SOC) scores, and thus would be expected to have good ability to handle the stress of prenatal diagnosis (PD). Prenatal diagnosis of hemophilia by CVS was generally well accepted by the women and their spouses. However, the period while waiting for test results was experienced as emotionally troublesome by both the women and their spouses; women reporting significantly more psychiatric or psychosomatic symptoms than men. Positive effects resulting from participation by the spouse on how the women experienced PD could not be identified. Selective abortion after first trimester PD was clearly experienced as emotionally painful by both the women and their spouses, these reactions being similar to, but not as pronounced as those found after second trimester selective abortion. Notably, signs of depressive mood were observed several years after the abortion, and the provision of psychosocial support should be recommended for couples who decide upon termination of pregnancy following PD.</p>},
  author       = {Tedgård, Ulf and Ljung, R. and McNeil, T. F.},
  issn         = {0009-9163},
  keyword      = {Chorionic villus sampling,Hemophilia,Prenatal diagnosis,Psychology,Sense of coherence,Spouse},
  language     = {eng},
  number       = {1},
  pages        = {26--33},
  publisher    = {ARRAY(0xc642390)},
  series       = {Clinical Genetics},
  title        = {How do carriers of hemophilia and their spouses experience prenatal diagnosis by chorionic villus sampling?},
  volume       = {55},
  year         = {1999},
}