1.1 30 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 CF Bergman author Lithosphere and Biosphere Science v1000635 department Late Ordovician jawed polychaete (Annelida) faunas from the type Cincinnatian region in the tri-state area of Indiana, Ohio. and Kentucky, North America, are discussed on the basis of an extensive and unique collection of more than 50,000 well-preserved scolecodonts. Approximately 40 to 50 multi-element species belonging to a dozen families are identified. Scolecodonts of polychaetes with prionognath, and particularly labidognath, type of jaw apparatus markedly dominate, whereas those of placognath and ctenognath taxa are very rare. The most common and/or characteristic genera include Oenonites Hinde, 1879; Kettnerites Zebera, 1935; Atrakoprion, Kielan-Jaworowska, 1962; Ramphoprion Kielan-Jaworowska, 1962; Protarabellites Stauffer, 1933a; Kalloprion, Kielan-Jaworoska. 1962: Leptoprion, Kielan-Jaworowska, 1966; Hadoprion Eriksson and Bergman, 1998; Mochtyella Kielan-Jaworowska, 1961: and Tetraprion? Kielan-Jaworowska, 1966. Members of the family Polychaetaspidae, particularly Oenonites species, generally dominate in abundance and number of species. The second most abundant family typically is either Ramphoprionidae or Paulinitidae. Overall. the taxonomic diversity seems to increase from the deeper water, shale-dominated, Edenian Kope Formation and upward in the succession to the shallower water, limestone-dominated, Richmondian Whitewater Formation. Five more or less distinct scolecodont associations were identified that are of potential biostratigraphic utility. Most families and genera identified have intercontinental distribution and can be identified also in approximately coeval strata of the Baltic paleocontinent. However, the faunal composition differs between these regions, especially at the species level. https://portal.research.lu.se/en/publications/c3c33057-7404-488e-b407-402f3beb2cb7 Cambridge University Press 2003 eng Geology 0022-3360 309567 000183267700008 0038467451 10.1666/0022-3360(2003)077<0509:LOJPFO>2.0.CO;2 http://dx.doi.org/10.1666/0022-3360(2003)077<0509:LOJPFO>2.0.CO;2 yes 77 3 509 523 https://www.scopus.com/pages/publications/0038467451 c3c33057-7404-488e-b407-402f3beb2cb7 2016-04-01T15:36:19+02:00 2025-10-14T11:15:13+02:00 2016-04-01T15:36:19+02:00 1 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 C F Bergman author Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 Lithosphere and Biosphere Science v1000635 department Jaws of fossil marine polychaete annelids, scolecodonts, from Sweden have chiefly been reported from Silurian strata. The specimens described in this paper come from Upper Danian (Paleocene) strata of the Limhamn quarry in Skane (Scania), the southernmost province of Sweden. The jaws are assigned to the Recent genera Glycera and Drilonereis, but their state of preservation did not allow species identification. The low diversity fauna is almost exclusively composed of Glycera sp. It differs conspicuously in taxonomical composition from Palaeozoic assemblages and exhibits close affinity to other Mesozoic and Cenozoic faunas as well as and modern ones. https://portal.research.lu.se/en/publications/dbadeb63-851f-4fbc-9e85-084ea59c3e10 Taylor & Francis 2003 eng Skane Paleocene Danian Drilonereis Glycera polychaetes scolecodonts Sweden Geology http://www.gff-online.se/site/article.asp?articleID=737 yes 2000-0863 297275 000186251500005 3843084247 125 3 163 167 https://www.scopus.com/pages/publications/3843084247 dbadeb63-851f-4fbc-9e85-084ea59c3e10 2016-04-01T12:16:19+02:00 2025-10-14T10:52:00+02:00 2016-04-01T12:16:19+02:00 2 info:srw/schema/1/mods-v3.3xml journalArticle published yes 5 Charlotta Sundblad author Mikael Landén author Tomas Eriksson author 2845faf3-a6f1-4c73-bcf3-66883828a3df Lars Bergman author Elias Eriksson author The Biological Psychiatry Research Group v1000539 department The Biological Psychiatry Research Group research group colon; Prompted by previous studies suggesting that bulimia nervosa in women may be associated with elevated serum levels of testosterone, we have evaluated the possible effect of androgen antagonism in this condition. To this end, women meeting the DSM-IV criteria of bulimia nervosa, purging type, were treated in a one-center study with the androgen receptor antagonist flutamide (n = 9), the serotonin reuptake inhibitor citalopram (n = 15), flutamide plus citalopram (n = 10), or placebo (n = 12) for 3 months using a double-blind design. Self-rated global assessment of symptom intensity suggests all active treatments to be superior to placebo. The reduction in binge eating compared with baseline was statistically significant in both groups given flutamide but not in the groups given citalopram only or placebo. A moderate and reversible increase in serum transaminase levels led to discontinuation in two subjects in the flutamide group. It is concluded that blockade of androgen receptors may reduce some of the symptoms of bulimia nervosa in women. https://portal.research.lu.se/en/publications/af08a914-4abc-48e6-aaa0-5ca29859414f Lippincott Williams & Wilkins 2005 eng Pharmacology and Toxicology http://www.psychopharmacology.com/pt/re/jclnpsychopharm/abstract.00004714-200502000-00013.htm yes 0271-0749 133225 000226451200013 15643104 12344287791 10.1097/01.jcp.0000150222.31007.a9 http://dx.doi.org/10.1097/01.jcp.0000150222.31007.a9 yes 25 1 85 88 https://www.scopus.com/pages/publications/12344287791 af08a914-4abc-48e6-aaa0-5ca29859414f 2016-04-01T15:48:56+02:00 2025-10-14T11:45:32+02:00 2016-04-01T15:48:56+02:00 3 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 CF Bergman author Lennart Jeppsson author 2949462f-4cd7-4c69-9455-96415da621b2 Lithosphere and Biosphere Science v1000635 department Scolecodonts, polychaete jaws, generally occur abundantly in Silurian shallow marine successions and are known from all continents except Antarctica. The assemblages are typically characterized by taxa with labidognath, placognath and prionognath type jaw apparatuses. They commonly include species of Kettnerites Zebera, 1935, Oenonites Hinde, 1879, Mochtyella Kielan-Jaworowska, 1961, Protarabellites Stauffer, 1933, Atraktoprion Kielan-Jaworowska, 1962, Pistoprion Kielan-Jaworowska, 1966, Vistulella Kielan-Jaworowska, 1961, Xanioprion Kielan-Jaworowska, 1962, Kalloprion Kielan-Jaworowska, 1962, and Leptoprion Kielan-Jaworowska, 1966. Less common genera, such as Hadoprion Eriksson and Bergman, 1998, Symmetroprion Kielan-Jaworowska, 1966 and Rhytiprion Kielan-Jaworowska, 1966, generally are recorded only from very large collections and/or suitable facies. Many of the common genera, as well as a few species, have been identified in several regions, particularly in Baltica and Laurentia, and evidently had a broad, intercontinental distribution. However, the scolecodont record from regions at higher paleolatitudes, i.e. Gondwana and peripheral paleoplates, is meager. In the famous latest Llandovery to latest Ludlow succession of Gotland, Sweden, scolecodonts are one of the most common microfossil groups, with abundances reaching thousands of specimens/kg rock. Based on an extensive collection, approximately one hundred jawed polychaete species belonging to at least 28 genera and a dozen families have been identified. Polychaetaspids, paulinitids and mochtyellids dominate. The exceptionally rare genus Synclinophora Eisenack, 1975, may belong to the family Oenonidae. If so, this is the only extant family represented in Silurian strata. The diversity patterns and temporal and stratigaphic distribution related to facies reveal that the assemblages house eurytopic as well as stenotopic taxa. Both long-ranging taxa, embracing the entire succession and beyond, and short-ranging taxa, occur. Like other metazoan groups, jawed polychaetes were affected by the documented Silurian extinction events. During the globally recognized late Ludlow Lau Event, approximately one third of the identified polychaete taxa went extinct, and some lineages show Lazarus gaps on Gotland. (C) 2004 Elsevier B.V. All rights reserved. https://portal.research.lu.se/en/publications/c42fafe8-ddbb-49c9-a404-2aff1c6e06f9 Elsevier 2004 eng Polychaete jaws polychaeta scolecodonts Silurian Geology 0034-6667 268286 000223569200006 3543058823 10.1016/j.revpalbo.2004.04.001 http://dx.doi.org/10.1016/j.revpalbo.2004.04.001 yes 131 3-4 269 300 https://www.scopus.com/pages/publications/3543058823 c42fafe8-ddbb-49c9-a404-2aff1c6e06f9 2016-04-01T15:37:33+02:00 2025-10-14T11:35:58+02:00 2016-04-01T15:37:33+02:00 4 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 SA Leslie author CF Bergman author Lithosphere and Biosphere Science v1000635 department A jawed polychaete fauna from the upper 30 in of the Upper Ordovician Sylvan Shale (Richmondian, Ash-ill) of Oklahoma is described, based on recovered scolecodonts (polychaete jaws). The fauna includes members of six families: Paulinitidae, Ramphoprionidae, Polychaetaspidae, Atraktoprionidae, Hadoprionidae, and Kalloprionidae. Ten species are identified and one new paulinitid species, Ketmerites (Aeolus) sylvanensis, dominates. The low-abundance and relatively low-diversity Sylvan Shale fauna differs from approximately coeval ones of both Laurentia and Baltica, particularly by its high relative frequency of paulinitids. The scolecodonts are associated with chitinozoans, as well as some enmnatic organic-walled microfossils. Conodonts are extremely rare. with Plectodina tenuis, Amorphognathus sp., and Dapsilodus sp. identified. https://portal.research.lu.se/en/publications/faa4501a-ee04-4645-96e6-5cca319cbbe4 Cambridge University Press 2005 eng Geology http://jpaleontol.geoscienceworld.org/cgi/content/abstract/79/3/486 yes 0022-3360 244350 000228613300005 18644370208 79 3 486 496 https://www.scopus.com/pages/publications/18644370208 faa4501a-ee04-4645-96e6-5cca319cbbe4 2016-04-01T17:09:18+02:00 2025-10-14T12:44:24+02:00 2016-04-01T17:09:18+02:00 5 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 Olle Hints author Claes F. Bergman author Lithosphere and Biosphere Science v1000635 department The polychaete annelid Kingnites diamondi, a new paulinitid genus and species, is described from the Silurian of Baltoscandia. Its large maxillae differ morphologically from those of all other known paulinitids, particularly in being very elongate and having conspicuous myocoele openings and posterior portions of the first maxillae (MI). Albeit rare, this polychaete taxon is highly characteristic and appears to be confined to the Wenlock-Ludlow transitional interval on Gotland, Sweden, and ranges into the upper Ludlow on Saaremaa, Estonia. All samples yielding this species derive from strata formed in proximal carbonate platform environments. The temporal and geographical distribution indicates that it first appeared in Gotland and subsequently spread north-eastwards to the present-day Saaremaa. Kingnites diamondi adds to the list of known members of the Paulinitidae and reinforces the importance of this family, in terms of abundance and diversity, in Silurian polychaete faunas of Baltica. This is the biggest paulinitid recorded from the Silurian with an inferred body length of approximately half a metre and its diagnostic jaws may serve as a proxy for shallow water, backreef (marginal marine to lagoonal) environments. https://portal.research.lu.se/en/publications/df3ab7c8-36e8-40a8-925b-355405f2bf4b Taylor & Francis 2012 eng scolecodonts polychaetes paulinitids proximal carbonate platform environment Silurian Baltoscandia Geology 2000-0863 3191638 000309123300004 84866751247 10.1080/11035897.2012.704066 http://dx.doi.org/10.1080/11035897.2012.704066 yes 134 3 217 224 https://www.scopus.com/pages/publications/84866751247 df3ab7c8-36e8-40a8-925b-355405f2bf4b 2016-04-01T10:00:14+02:00 2025-10-14T09:47:22+02:00 2016-04-01T10:00:14+02:00 6 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 C F Bergman author Mats Eriksson author c4d0dbd0-2ec2-46b4-bbe6-b87549717793 Mikael Calner author ca0fcf4c-7556-41f8-a06a-4e02600a1d20 Lithosphere and Biosphere Science v1000635 department The Ordovician jawed polychaete annelid Rhytiprion magnus has hitherto been recorded in erratic boulders of probable East Baltic provenance and in drill cores from Poland and North Estonia. In this study the stratigraphical range and geographical distribution are extended as R. magnus is recorded from the Silurian of Gotland (Sweden) and Indiana (U.S.A.). Hence, R. magnus is now known from the Middle Ordovician to the middle Silurian (lower Ludlow; Kockelella v. variabilis conodont Zone) and comprises one of the few Palaeozoic polychaete species with a documented intercontinental distribution. The species is generally very rare but is abundant at a few localities; on Gotland, in the offshore setting of the Late Wenlock (K. ortus absidata conodont Zone; Colonograptus? praedubeli graptolite Zone) Djupvik Member of the Halla Formation. The distribution pattern shows that R. magnus thrived in low energy, distal platform environments, in which marly and muddy terrigenous sediments accumulated. https://portal.research.lu.se/en/publications/dcbd6cde-9e3c-4f40-a43a-15665814393b Taylor & Francis 2003 eng Gotland Silurian Rhytiprion scolecodonts polychaete jaws USA Indiana Sweden Geology http://www.gff-online.se/site/article.asp?articleID=717 yes 2000-0863 286143 000189262300002 3543054570 125 4 191 199 https://www.scopus.com/pages/publications/3543054570 dcbd6cde-9e3c-4f40-a43a-15665814393b 2016-04-01T11:37:35+02:00 2025-10-14T10:43:22+02:00 2016-04-01T11:37:35+02:00 7 info:srw/schema/1/mods-v3.3xml book chapter published 4 Michael Bogdan author a1d96f0f-2136-4ce0-ab28-90ee68ae6d73 C Bergman author A Eriksson author J Hirschfeldt author Dispute resolution v1001519 department Department of Law v1000142 department Dispute resolution research group https://portal.research.lu.se/en/publications/6045768d-d73f-45c3-8eb4-5bcde44f065e 2008 swe internationell privaträtt private international law Law 1370197 6045768d-d73f-45c3-8eb4-5bcde44f065e 2016-04-04T12:58:32+02:00 2025-04-04T13:55:16+02:00 2016-04-04T12:58:32+02:00 8 info:srw/schema/1/mods-v3.3xml journalArticle published yes 4 Ulrika Järkestig-Berggren author Ann Sofie Bergman author Maria Eriksson author Gisela Priebe author da03d660-c3ec-4715-bb84-c0f91267a94b Department of Psychology v1000681 department <p>Children who have parents with any kind of illness may become young carers who take a responsibility not expected of children for household tasks, or personal or emotional care for parents and siblings. So far, little is known about children in Sweden who are at risk of becoming young carers. The aim of this article is therefore to explore the extent and impact of children's caring activities as reported in a pilot study by a sample of children in Sweden. A number of international questionnaires measuring the amount of caring activities, impact of caring, quality of life, and psychological well-being were translated and combined into a survey. The pilot survey was completed by 30 children 10–18 years of age. Also, when completing the survey, the children were interviewed concerning their experiences of caregiving. The participants report on a group level emotional symptoms such as fear and nervousness above the clinical cut-off value. They also rate a lower level of caring compared with findings from the United Kingdom, but they report a higher degree of negative impact of caring than young carers in the United Kingdom.</p> https://portal.research.lu.se/en/publications/3306b67d-5f42-482c-9cd4-492709bda895 Wiley-Blackwell 2019 eng care activities child protection impact of caring psychological wellbeing young carers youth Social Work Pediatrics Other Health Sciences 1356-7500 85055089285 10.1111/cfs.12614 http://dx.doi.org/10.1111/cfs.12614 yes 24 2 292 300 https://www.scopus.com/pages/publications/85055089285 3306b67d-5f42-482c-9cd4-492709bda895 2018-12-10T14:22:32+01:00 2025-10-14T13:28:57+02:00 2018-12-10T14:22:32+01:00 9 info:srw/schema/1/mods-v3.3xml journalArticle published yes 8 Fanny Bergman author 5e305b40-a11f-460c-a029-22b571e12ed4 Axel C. Eriksson author e20446b9-4411-46ea-8cc6-ab4545dc11c8 Marten Spanne author Lena Ohlsson author c118ad48-f0f1-49a9-83d8-c5ee4287db98 Irma Mahmutovic Persson author 27a056b4-08a8-41c8-b734-ddb31340a455 Lena Uller author b7a9d28a-79d1-486c-bbec-27534a2d3f61 Jenny Rissler author 18e92696-32fc-4edd-80ed-da7f82295054 Christina Isaxon author afd05691-77d1-4aad-8657-373525b53459 LTH Profile Area: Circular Building Sector v1001506 department LU Profile Area: Light and Materials v1001531 department LTH Profile Area: Aerosols v1001503 department Department of Clinical Sciences, Lund v1000428 department Ergonomics and Aerosol Technology v1000237 department MERGE: ModElling the Regional and Global Earth system v1000618 department NanoLund: Centre for Nanoscience v1000190 department Metalund v1000189 department LTH Profile Area: Nanoscience and Semiconductor Technology v1001504 department LTH Profile Area: The Energy Transition v1001508 department Experimental Vascular Research v1000985 department LUCC: Lund University Cancer Centre v1001347 department Respiratory Immunopharmacology v1000401 department Centre for Healthy Indoor Environments v1001412 department Experimental Vascular Research research group Respiratory Immunopharmacology research group <p>The toxicity of particulate matter (PM) is dependent on particle physical and chemical properties and is commonly studied using in vivo and in vitro approaches. PM to be used for in vivo and in vitro studies is often collected on filters and then extracted from the filter surface using a solvent. During extraction and further PM sample handling, particle properties change, but this is often neglected in toxicology studies, with possible implications for health effect assessment. To address the current lack of knowledge and investigate changes in particle properties further, ambient PM with diameter less than 2.5 μm (PM_2.5) was collected on filters at an urban site and extracted using a standard methanol protocol. After extraction, the PM was dried, dispersed in water and subsequently nebulized. The resulting aerosol properties were then compared to those of the ambient PM_2.5. The number size distribution for the nebulized aerosol resembled the ambient in terms of the main mode diameter, and &gt;90 % of particle mass in the nebulized size distribution was still in the PM_2.5 range. Black carbon made up a similar fraction of PM mass in nebulized as in ambient aerosol. The sulfate content in the nebulized aerosol seemed depleted and the chemical composition of the organic fraction was altered, but it remains unclear to what extent other non-refractory components were affected by the extraction process. Trace elements were not distributed equally across size fractions, neither in ambient nor nebulized PM. Change in chemical form was studied for zinc, copper and iron. The form did not appear to be different between the ambient and nebulized PM for iron and copper, but seemed altered for zinc. Although many of the studied properties were reasonably well preserved, it is clear that the PM_2.5 collection and re-aerosolization process affects particles, and thus potentially also their health effects. Because of this, the effect of the particle collection and extraction process must be considered when evaluating cellular and physiological outcomes upon PM_2.5 exposure.</p> https://portal.research.lu.se/en/publications/37e5d911-a0d3-47cb-90ae-e3bf68911893 Elsevier 2024-09 eng Air pollution Chemical speciation Inhalation toxicology Methanol extraction XANES Other Chemistry Topics 0021-8502 85196408742 10.1016/j.jaerosci.2024.106416 http://dx.doi.org/10.1016/j.jaerosci.2024.106416 181 106416 https://www.scopus.com/pages/publications/85196408742 37e5d911-a0d3-47cb-90ae-e3bf68911893 2024-07-01T15:10:09+02:00 2026-03-12T00:34:07+01:00 2024-07-01T15:10:09+02:00 10 info:srw/schema/1/mods-v3.3xml journalArticle published yes 9 Anders Forss author Gabriella Bröms author David Bergman author Marcus Thuresson author Jiangwei Sun author Carl Eriksson author Ola Olén author Bengt Zöller author 03dce51c-06b6-47fe-929a-a281cc7af269 Jonas F. Ludvigsson author Family medicine, cardiovascular medicine and genetics v1001322 department EpiHealth: Epidemiology for Health v1001239 department Family medicine, cardiovascular medicine and genetics research group <p>Introduction: Inflammatory diseases have been associated with increased risk of venous thromboembolism (VTE). However, data on VTE is lacking in large population-based cohorts of microscopic colitis (MC). Methods: This study included all Swedish adults with incident MC without prior VTE (1990-2017; n=12,489; follow-up until 2021). MC and subtypes (collagenous colitis and lymphocytic colitis) were defined from prospectively recorded colorectal histopathology reports from all 28 pathology departments in Sweden. Individuals with MC were matched for birth year, sex, calendar year and county with up to five general population reference individuals (n=55, 809) without prior MC. Sensitivity analyses included full sibling comparisons and stricter definitions of VTE requiring a primary diagnosis of VTE and a prescription of anticoagulant medication. Incidence rates and multivariable-adjusted hazard ratios (aHRs) and 95% confidence intervals (CI) for VTE events were calculated using Cox proportional hazards modelling. Results: Over a median of 10.0 years of follow-up, 755 (6.0%; 11.3/1000 person-years) incident VTE events occured in individuals with MC and 2674 (4.8%; 8.6/1000 person-years) in reference individuals. Individuals with MC had a higher overall relative risk of any VTE event compared with reference individuals (aHR=1.21, 95%CI=1.11-1.32) including higher risk of pulmonary embolism (aHR=1.23, 95%CI=1.08-1.40), deep vein thrombosis of the legs (aHR=1.16, 95%CI=1.03-1.32), and other VTE events (aHR=1.31, 95%CI=1.08-1.58). The results remained robust in sensitivity analyses. Discussion: In this population-based study, individuals with MC had a 21% higher risk of VTE compared with reference individuals, equivalent to one extra VTE event for every 37 MC individuals followed for ten years.</p> https://portal.research.lu.se/en/publications/1103d8bb-469f-409d-adbb-60801769eb4f Wolters Kluwer 2025 eng biopsy epidemiology inflammatory bowel disease microscopic colitis venous thromboembolism Cardiology and Cardiovascular Disease 0002-9270 105003039962 40079472 10.14309/ajg.0000000000003408 http://dx.doi.org/10.14309/ajg.0000000000003408 yes 120 12 2867 2876 https://www.scopus.com/pages/publications/105003039962 1103d8bb-469f-409d-adbb-60801769eb4f 2025-09-01T12:25:30+02:00 2026-05-26T17:12:25+02:00 2025-09-01T12:25:30+02:00 11 info:srw/schema/1/mods-v3.3xml journalArticle published yes 9 Christer Eriksson author Lars Frangsmyr author Liza Danielsson Niemi author Vuokko Loimaranta author Ulf Holmskov author Tomas Bergman author Hakon Leffler author af927e79-46c7-4e78-b915-e5d21e0ed62e Howard F. Jenkinson author Nicklas Stromberg author Division of Microbiology, Immunology and Glycobiology - MIG v1000557 department Glycoprotein gp-340 aggregates bacteria in saliva as part of innate defence at mucosal surfaces. We have detected size- and glycoforms of gp-340 between human saliva samples (n=7) and lung gp-340 from a proteinosis patient using antibodies and lectins in Western blots and ELISA measurements. Western blots of saliva samples, and of gp-340 purified, from the seven donors using a gp-340 specific antibody distinguished four gp-340 size variants, designated I to IV (n=2,2,2 and 1). While saliva gp-340 variants I to III had single bands of increasing sizes, variant IV and lung gp-340 had double bands. Purified I to IV proteins all revealed a N-terminal sequence TGGWIP upon Edman degradation. Moreover, purified gp-340 from the seven donors and lung gp-340 shared N-glycans, sialylated Gal beta 1-3GalNAc and (poly)lactosamine structures. However, the larger size gp-340 grouping II/III (n=4) and smaller size grouping I/IV correlated with a secretor, Se(+), and a non secretor, Se(-), dependent glycoform of gp-340, respectively (p=0.03). The Se(+) glycoforms contained ABH, Le(b), Le(y) and polylactosamine structures, while the Se(-) glycoforms lacked ABH antigens but expressed Lea, Lex and lactosamine structures. By contrast, lung gp- 340 completely lacked ABH, Le(a/b), Le(x/y) or sLe(x) structures. Gp-340 and secretor typing of saliva from additional donors (n=29) showed gp-340 glycoforms I to IV for 6, 16, 4 and 0 donors, respectively, and 3 non-typeable donors, and verified that gp-340 glycoforms I and II/III correlate with Se(-) and Se(+) phenotypes, respectively (p &lt; 0.0001). The glycoforms of saliva and lung gp-340 mediated differential aggregation of Le(b)-(Helicobacter pylori), sialylpolylactosamine(Streptococcus suis) or sialic acid- (Streptococcus mutans) binding bacteria. In conclusion, variant size- and glycoforms of gp-340 are expressed by different individuals and may modulate the biological properties of gp-340 pertinent to health and disease. https://portal.research.lu.se/en/publications/46a36f4f-6a89-472a-ad46-b9412ddab710 Springer 2007 eng glycoforms secretor status DMBT1 saliva Gp-340 Microbiology in the Medical Area Immunology in the Medical Area (including Cell and Immunotherapy) 1573-4986 671676 000244681000003 33847664676 10.1007/s10719-006-9020-1 http://dx.doi.org/10.1007/s10719-006-9020-1 yes 24 2-3 131 142 https://www.scopus.com/pages/publications/33847664676 46a36f4f-6a89-472a-ad46-b9412ddab710 2016-04-01T16:40:40+02:00 2025-10-14T09:45:11+02:00 2016-04-01T16:40:40+02:00 12 info:srw/schema/1/mods-v3.3xml journalArticle published yes 8 Manan Pareek author Deepak L. Bhatt author Mette L. Nielsen author Ram Jagannathan author Karl Fredrik Eriksson author 40ca18b6-33b2-494d-9bd0-376fadb439bc Peter M. Nilsson author d4f81cfb-cf32-492f-991f-f84f66734b69 Michael Bergman author Michael H. Olsen author Translational Muscle Research v1000486 department Internal Medicine - Epidemiology v1000520 department EpiHealth: Epidemiology for Health v1001239 department Translational Muscle Research research group Internal Medicine - Epidemiology research group <p>OBJECTIVE To examine whether the 1-h blood glucose measurement would be a more suitable screening tool for assessing the risk of diabetes and its complications than the 2-h measurement. RESEARCH DESIGN AND METHODS We conducted a prospective population-based cohort study of 4,867men, randomly selected fromprespecified birth cohorts between 1921 and 1949,who underwent an oral glucose tolerance test with blood glucose measurements at 0, 1, and 2 h. Subjects were followed for up to 39 years, with registry-based recording of events. Discriminative abilities of elevated 1-h (≥8.6 mmol/L) versus 2-h (≥7.8 mmol/L) glucose for predicting incident type 2 diabetes, vascular complications, andmortality were compared using Kaplan-Meier analysis, Cox proportional hazards regression, and net reclassification improvement. RESULTS Median agewas 48 years (interquartile range [IQR] 48-49). During follow-up (median 33 years [IQR 24-37]), 636 (13%) developed type 2 diabetes. Elevated 1-h glucose was associatedwith incident diabetes (hazard ratio 3.40 [95% CI 2.90-3.98], P &lt; 0.001) and provided better risk assessment than impaired glucose tolerance (Harrell concordance index 0.637 vs. 0.511, P &lt; 0.001). Addition of a 1-hmeasurement in subjects stratified by fasting glucose provided greater net reclassification improvement than the addition of a 2-h measurement (0.214 vs. 0.016, respectively). Finally, the 1-h glucose was significantly associated with vascular complications and mortality. CONCLUSIONS The 1-h blood glucose level is a stronger predictor of future type 2 diabetes than the 2-h level and is associated with diabetes complications and mortality.</p> https://portal.research.lu.se/en/publications/c425b721-e539-4e88-8475-dd9c4af51632 American Diabetes Association 2018 eng Endocrinology and Diabetes 0149-5992 85038961961 29138275 10.2337/dc17-1351 http://dx.doi.org/10.2337/dc17-1351 yes 41 1 171 177 7 https://www.scopus.com/pages/publications/85038961961 c425b721-e539-4e88-8475-dd9c4af51632 2018-01-22T10:43:29+01:00 2026-05-14T04:11:57+02:00 2018-01-22T10:43:29+01:00 13 info:srw/schema/1/mods-v3.3xml report published 12 Maj Rundlöf author 489fcb0f-8290-4d6b-9a1d-4a76de0116da Elin Eriksson author Julia Bergman author Sara Erling author Ove Jonsson author Mariana Ledesma author Laima Blažytė-Čereškienė author Bjørn Arild Hatteland author Glenn Svensson author ce2893e6-ce7a-4ea5-99ad-c470b874d884 Kajsa Weslien author Ola Olsson author 94840950-4319-4fbc-9c64-4d2a50411530 Mikaela Gönczi author Biodiversity and Evolution v1001670 department LU Profile Area: Nature-based future solutions v1001534 department Biodiversity and Conservation Science v1001394 department BECC: Biodiversity and Ecosystem services in a Changing Climate v1000616 department Sensory Biology v1001667 department Pheromone Group v1001399 department Biodiversity and Conservation Science research group Pheromone Group research group Understanding pesticide-Pollinator interactions to support EU Environmental Risk Assessment and policy project https://portal.research.lu.se/en/publications/6d84b95f-96da-425d-b302-9a706064311d 1 SLU Centrum för kemiska bekämpningsmedel i miljön (CKB) 2025 eng Ecology (including Biodiversity Conservation) Environmental Sciences https://res.slu.se/id/publ/141272 978-91-8046-615-8 10.54612/a.5rg2oa0c6g http://dx.doi.org/10.54612/a.5rg2oa0c6g 2025 46 6d84b95f-96da-425d-b302-9a706064311d 2025-05-08T10:24:28+02:00 2025-05-09T03:06:05+02:00 2025-05-08T10:24:28+02:00 14 info:srw/schema/1/mods-v3.3xml journalArticle published yes 13 P Sandin author B E Bengtsson author Å Bergman author I Brandt author L Dencker author P Eriksson author L Förlin author Per Larsson author 40bf7c98-04af-4a8e-9951-e78f00a6ada2 A Oskarsson author C Ruden author Anders Södergren author a5cd8f9c-6085-4889-8923-07a524be2950 Per Woin author ecbad2c5-71cd-4365-bbc4-341d0c10fb80 S O Hansson author Department of Biology v1000601 department In order to give adequate support to risk managers, new risk assessment methods should be developed that are (1) scientifically sound, (2) simplified, and (3) suited for precautionary risk management. In this Perspective we propose that the notion of a precautionary default can be a useful tool in the development of such methods. A precautionary default is a cautious or pessimistic assumption that is used in the absence of adequate information and that should be replaced when such information is obtained. Furthermore, we point out some promising research areas for the development of such indicators, viz. connections between chemical characteristics such as persistence and effect parameters, monitoring of contaminants in polar regions, monitoring of contaminants in breast milk, application of results from (human) toxicology in ecotoxicology and vice versa, (eco) toxicological test systems that are sensitive to effects on reproduction, and the application of bioinformatic methods to complex data, both in genomic research and in ecotoxicology. We conclude that precautionary decision-making does not require less science, but to the contrary it requires more science and improved communication between scientists and risk managers. https://portal.research.lu.se/en/publications/15befcb6-ba21-4809-8cfc-edcdaa531246 Taylor & Francis 2004 eng Ecology (including Biodiversity Conservation) 1080-7039 149744 000220374200001 1642370560 10.1080/10807030490280909 http://dx.doi.org/10.1080/10807030490280909 yes 10 1 1 18 https://www.scopus.com/pages/publications/1642370560 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Chemical Ecology/Ecotoxicology (Closed 2011) (011006020) 15befcb6-ba21-4809-8cfc-edcdaa531246 2016-04-01T16:08:18+02:00 2025-10-14T10:46:47+02:00 2016-04-01T16:08:18+02:00 15 info:srw/schema/1/mods-v3.3xml journalArticle published yes 21 Qiao Sen Chen author Hanna M. Björck author Otto Bergman author Damiano Baldassarre author Gunnar Engström author 550b9ecd-b6eb-4a08-95c5-937f82d4bc04 Antonio Gallo author Anders Gummesson author Ulf Hedin author Sudhir Kurl author Lars Lind author Ljubica Matic author Douw Johannes Mulder author Matteo Pirro author Kai Savonen author Stefan Söderberg author Fabrizio Veglia author Elena Tremoli author Carl Johan Östgren author Per Eriksson author Rona J. Strawbridge author Bruna Gigante author Cardiovascular Research - Epidemiology v1000501 department EpiHealth: Epidemiology for Health v1001239 department Department of Clinical Sciences, Lund v1000428 department Cardiovascular Research - Epidemiology research group <p>Aims Endotypes integrate individual clinical and molecular data and can be used to formulate molecular subclassifications of diseases. We previously derived four endotypes of subclinical carotid atherosclerosis in a large European cohort, c-IMT and c-IMT Progression as Predictors of Vascular Events in a High-Risk European Population (IMPROVE), identifying individuals with a specific cardiovascular (CV) risk, ranging from low (endotype 1) to very high (endotype 4). Here, we investigate the mechanisms underlying the differences in CV risk observed across these four endotypes. Methods and results We validated the four endotypes in SCAPIS (n = 5050) and UK Biobank (n = 50 396) using carotid plaque and carotid intima-media thickness (c-IMT) as subclinical atherosclerosis measures. Endotype 4 associated with a larger number of carotid plaques and increased c-IMT measures as compared to endotype 1. We performed a meta-analysis of individual genome wide association studies in IMPROVE (n = 3711), SCAPIS and UK Biobank, and identified 12 SNPs associated with endotypes. We investigated if they regulated gene expression and circulating protein levels. We found that rs2228145A/C at Interleukin-6 Receptor (IL6R), associated with endotype 4, regulated IL6R expression and circulating levels of OncoStatin M Receptor (OSMR), Complement Factor B (CFB) and Fibrinogen Chain A (FGA). We used rs2228145A/C as an instrument in two-sample Mendelian randomization analyses and showed that a decreasing IL6R expression, associated with increasing CFB, FGA, and OSMR circulating levels. Endotype 4, IL6R, CFB, FGA, and OSMR co-localized within 250 kb surrounding rs2228145A/C. However, only OSMR was up-regulated in advanced carotid atherosclerotic plaques in the presence of the A allele and in aortic region exposed to low wall shear stress. In the UK Biobank, we observed that each additional A allele at rs2228145 increased by 1.28-times the risk of myocardial infarction (MI) in endotype 4. Conclusion Rs2228145A/C associated with endotype 4 clinical and molecular characteristics and amplified the MI risk in individuals assigned to endotype 4. These effects appeared to be mediated by a crosstalk with OSMR.</p> https://portal.research.lu.se/en/publications/7488d75d-8713-4e93-887a-8f1ef8319514 Oxford University Press 2025-11-01 eng Endotype Genome-wide association Omics Subclinical atherosclerosis Cardiology and Cardiovascular Disease 0008-6363 105024495310 41124095 10.1093/cvr/cvaf177 http://dx.doi.org/10.1093/cvr/cvaf177 121 15 2360 2373 14 https://www.scopus.com/pages/publications/105024495310 Publisher Copyright: © The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. 7488d75d-8713-4e93-887a-8f1ef8319514 2026-02-17T16:51:04+01:00 2026-05-27T06:55:41+02:00 2026-02-17T16:51:04+01:00 16 info:srw/schema/1/mods-v3.3xml newspaper article published general 420 Glenn Bark author Karin Gerhardt author Jeannette Eggers author Paul Glantz author Maria Wolrath Söderberg author Cecilia Lalander author Micael Grenholm author 902dd5d6-ee0d-4ada-9283-64329b087560 Alasdair Skelton author Isabelle Letellier author Lennart Olsson author 3026cb27-98ea-41f3-b4ea-e52bc1c2ca2f Johan Friberg author 967384ce-c05b-4d1e-876f-67f2a3f5ac1a Lovisa Nilsson author fc5fac5b-5317-4066-ab71-fd4f6266913a Per Becker author 18b9c383-1686-4c82-8b50-63b0cc471802 Ebba Malmqvist author 7c4c2eed-ba3c-493b-a30f-9a0dfc0a6c46 Kes Mccormick author 4e240d04-3c4f-4b67-ac7b-919eadae9152 Frans Libertson author b4499a76-a8b6-4e7a-adf5-2a470e16fa89 Thomas B Johansson author 4f6aa0c0-3aec-4ab9-b73e-789a4c5437f7 Gustav Osberg author 910a9bb1-1d20-4459-85ed-526b74ce9cfa Helen Avery author 9d7f4747-bc5a-47ce-b6b6-5a60ba2f4d50 Jonas Allesson author 90c2729d-5924-489c-8b0a-82ecdf7c615a Lina Lefstad author 071a87be-4bcb-414e-b5d7-f6b488822d52 Jonas Ardö author bd5ad253-9990-4613-afee-e94f24e17400 Anders Dahlner author 371b98a6-9830-4e3b-acb0-bbc4b94c5be6 Emilie Stroh author aa8ac21b-3fec-4294-96ab-c7a632eefaa2 Anna S. Persson author 5c4f0bef-bab1-4a96-888e-805e532fc501 Philipp Birken author 8aefd20b-c02f-412a-a755-badcec8b25f2 Anna-Riikka Kojonsaari author 7dcfe040-8e9a-4e91-805f-093373a09918 Abhishek Lodh author 25f4844c-812c-4093-bfbe-aa8d3ae0f9c2 Tomas Persson author 41523dc0-be27-4800-8a63-51feec5c39a9 Moa Sporre author 02c199e7-fd10-433f-9d28-8a0a79d963f2 Sara Gabrielsson author 181c3a02-6f8d-43be-812e-2d09b8bd4437 Carolina Rodriguez author c2b085f7-058e-4053-a07b-d6f92436a832 Lina Eklund author 42f4ecf4-1518-4445-be6d-116d047c3f9c Emma Kritzberg author 12e1c266-067d-499d-96b2-c857b5ccef73 Torsten Krause author 8256b44c-b528-412d-8857-d60cd8273b34 Ronald Byaruhanga author c9e4fe62-889f-4ffc-8c23-0d1a202a2792 Wilhelm May author 91652728-b609-4f50-a14d-a6acfc5a43ac Martijn van Praagh author 9ca4d0af-1690-4cd8-8aa5-d893949021e2 Henner Busch author 073f9806-b4f0-4157-92db-be278f950fe6 Matthias Lehner author 6a43a467-6953-4fab-99b5-7dc12adc6f0f Margarida Soares author 5b582cf8-11ac-413d-9bf9-1b7ebe288e49 Pontus Roldin author 8ae68db4-3b2b-440f-b594-9f36c5e93573 Juan Antonio Samper author 9b4ac3a1-78ee-4e72-ac48-97e1ff34cfb2 Veronica Hederström author 547c692f-fbb6-451f-8488-dc778d1d5adf Gustaf Olsson author 3cd36d9e-4204-4287-a4d2-d000284ae8b8 Johannes Stripple author 0c613d6d-bbe9-48d6-a08a-c2a9378c3d91 Dalia Abdelhady author 6df2df3a-e218-4340-8269-6ade22807be2 Nina Gren author c50684fe-2e8d-4a16-b936-207f8aaab366 Henrik Thorén author d4099fd4-d707-4688-a591-56174924116a Magnus Wiktorsson author 8931c483-bdc9-4709-a8f5-ebae7f4ee060 Sara Maad Sasane author 55970546-0d7a-4392-944d-43b41ff33178 Helena Elvén Eriksson author 0fc73d87-f2e6-44b3-bd79-c157120e64ea Christina Isaxon author afd05691-77d1-4aad-8657-373525b53459 Göran Frank author 80f5d867-ddb1-4bb9-aaa4-f74449186cce Johanna Yourstone author 65506875-a27c-42f4-ae20-51a30d3c2bcd Roger Hildingsson author d7959cf7-7da2-47fc-98aa-c84e9ed7870b David Alcer author eaacdd31-8878-45db-8e90-fc4ff476c21f Petter Kallioinen author 2d00075a-9845-48c5-9f40-72809dab149e Andreas Persson author 5a85d0c6-e187-4736-8297-862da2dc406c Linda Hartman author f2c62e18-9e53-4641-b2a4-d948761a7e77 Jessika Luth Richter author 5f16e763-3fe0-4e52-86bf-6c7c573a475e Jennifer B. Hinton author 3c031846-fc43-411c-8604-02c0e561c507 Max Koch author 4e809051-11d9-4d7a-952f-80f24b1e3458 Eskil Rydhe author 053eeb3c-b130-4651-a8cf-9958452bfe12 Barbara Magalhaes Teixeira author 6a73e3fc-155e-4437-9e83-c53d3626a2d7 Annika Bergman Rosamond author 45e5ebb8-b391-4237-9157-9d07fca0973d Linnea Lindh author 515ea24e-daa5-42cc-898d-454709eba8c7 Robin Sjökvist author 0ec08215-1738-40c3-88b0-3d926cac76a5 Church and Mission Studies v1000045 department LUCSUS (Lund University Centre for Sustainability Studies) v1000928 department Combustion Physics v1000625 department LU Profile Area: Nature-based future solutions v1001534 department Nuclear physics v1000629 department LU Profile Area: Light and Materials v1001531 department LTH Profile Area: Nanoscience and Semiconductor Technology v1001504 department NanoLund: Centre for Nanoscience v1000190 department Division of Risk Management and Societal Safety v1000224 department EpiHealth: Epidemiology for Health v1001239 department Planetary Health v1001286 department Division of Occupational and Environmental Medicine, Lund University v1000552 department CIRCLE v1001228 department The International Institute for Industrial Environmental Economics v1000927 department Centre for Environmental and Climate Science (CEC) v1000615 department Dept of Physical Geography and Ecosystem Science v1000639 department BECC: Biodiversity and Ecosystem services in a Changing Climate v1000616 department EPI@BIO v1001298 department Biodiversity and Conservation Science v1001394 department Mathematics (Faculty of Sciences) v1000666 department eSSENCE: The e-Science Collaboration v1001240 department Mathematics (Faculty of Engineering) v1000667 department MECW: The Middle East in the Contemporary World v1001242 department Centre for Advanced Middle Eastern Studies (CMES) v1001221 department Aquatic Ecology v1001370 department Division aquatic ecology v1000602 department LTH Profile Area: Water v1001583 department Division for Industrial Electrical Engineering and Automation v1000203 department Department of Political Science v1000693 department Sociology v1000692 department Social Anthropology v1000691 department Theoretical Philosophy v1000052 department Mathematical Statistics v1000668 department Unit for Educational Services v1001474 department Centre for Healthy Indoor Environments v1001412 department Metalund v1000189 department Ergonomics and Aerosol Technology v1000237 department Biodiversity v1000603 department Department of Physics v1000621 department Solid State Physics v1000623 department Cognitive Science v1000050 department Centre for Geographical Information Systems (GIS Centre) v1000640 department LTH Profile Area: Circular Building Sector v1001506 department Social Policy and Sustainability v1001317 department School of Social Work v1000688 department Chemical Physics v1000658 department Centre for Analysis and Synthesis v1000651 department et al. author Planetary Health research group EPI@BIO research group Biodiversity and Conservation Science research group Aquatic Ecology research group Postgrowth Welfare Systems project Partial Differential Equations project Harmonic Analysis and Applications project DEBATE. We researchers have long demanded that the government take climate research seriously and speed up the transition to a sustainable society.<br/>Instead, the government is pursuing a policy that deliberately increases emissions. Now more citizens need to raise their voices and show that we demand a knowledge-based climate transition, and it is urgent. https://portal.research.lu.se/en/publications/b7766fe7-2891-4115-9cb2-d3a6f96fa102 Aftonbladet Hierta AB 2023-11-30 swe Political Science (excluding Peace and Conflict Studies) Environmental Management Climate Science https://www.aftonbladet.se/debatt/a/EQ8nk2/420-forskare-regeringens-klimatpolitik-ar-katastrofal 1103-9000 b7766fe7-2891-4115-9cb2-d3a6f96fa102 2023-11-30T07:55:22+01:00 2026-02-12T07:26:22+01:00 2023-11-30T07:55:22+01:00 17 info:srw/schema/1/mods-v3.3xml newspaper article published general 1620 Christina Moberg author Hervé Corvellec author d332d8c0-631d-4861-a5a2-a50a0ef26321 Anders Lindroth author 1473e342-664a-4de2-a7eb-af3eedcf9517 Manuela Isacson author 301d5d1b-a2c8-4f0a-8fdc-805587721191 Linn Nilsson author f98729d5-8aef-491d-b46f-0941ae1fdd50 Kimberly Nicholas author 9addf4ef-2410-43a8-8097-0b108f370def Svante Björck author a4de58b7-57d9-437b-b244-4f9df387c13b Jayeon Lee author 3dc4daee-5f5f-4263-9545-c5b316635d7f Elisabeth Gerle author Martina Angela Caretta author 5bef3fe2-55eb-4cc8-9326-977f0fabb526 Diego Galafassi author e01d3024-5074-4ce2-a535-184a49146093 Alf Hornborg author f6c93a17-5bff-4b36-90e3-2cb119ea0d0d Sara Ullström author 96060ffe-0091-4c51-a2b1-d69a8ecb2c2c Lennart Olsson author 3026cb27-98ea-41f3-b4ea-e52bc1c2ca2f Anne Jerneck author 3069f94c-b7d5-48fe-aa1a-d9afbc82f6d9 Max Koch author 4e809051-11d9-4d7a-952f-80f24b1e3458 Pontus Roldin author 8ae68db4-3b2b-440f-b594-9f36c5e93573 Sune Sunesson author bea5b6a3-a6f3-4b52-b249-16d7c3f72ffc Emma Kritzberg author 12e1c266-067d-499d-96b2-c857b5ccef73 Dan Hammarlund author 92fb9b8f-2762-4668-86fe-77f1b3769e6b Christine Wamsler author 7b29fc32-3cef-4cc0-a641-541fb57533dd Torsten Krause author 8256b44c-b528-412d-8857-d60cd8273b34 Torbjörn Tyler author f2c3caaa-e5cc-44ad-94b9-03e2d097e4b1 Ebba Malmqvist author 7c4c2eed-ba3c-493b-a30f-9a0dfc0a6c46 Gustav Osberg author 910a9bb1-1d20-4459-85ed-526b74ce9cfa Katharina Reindl author f01edbba-04c1-4432-992a-4980bb5b51fd Lina Lefstad author 071a87be-4bcb-414e-b5d7-f6b488822d52 Caroline Björnerås author cafc3512-54e2-4dd0-a908-a7a584ed82c2 Salvatore Paolo De Rosa author f4be249b-4dd1-49ff-991e-cefcce06ea69 Till Koglin author 54550ac1-2742-46ff-9cea-e13954c60670 Tim Bjermo author b674a795-c1ce-47c2-b799-c52a8640cab4 Christina Isaxon author afd05691-77d1-4aad-8657-373525b53459 Ellinor Isgren author 5625a950-af5a-42f9-a512-7e98c8a2164d Jessika Luth Richter author 5f16e763-3fe0-4e52-86bf-6c7c573a475e Erik Johansson author 90fe63a9-e9a8-4d08-b319-1a4661e1b32d Martin Jarenmark author 33fecc52-5858-4709-82f2-f526fc224842 Johan Friberg author 967384ce-c05b-4d1e-876f-67f2a3f5ac1a David Wårlind author bc722af4-cb49-4e16-9f61-85c82c860ab4 Tullia Jack author e56d963d-c659-4984-83fb-e191ce8c5615 Karl Holmberg author 96b56535-c412-462d-af55-a15cabb87943 Annika Bergman Rosamond author 45e5ebb8-b391-4237-9157-9d07fca0973d Valentin Vogl author 6b273cd0-dbba-4013-b8c8-dfb16a12e733 Johanna Olofsson author 46e496ab-ba1a-4ca1-bbd7-57196db69204 Barbara Magalhaes Teixeira author 6a73e3fc-155e-4437-9e83-c53d3626a2d7 Ellen Palm author 8b304090-9cb5-4734-acd4-1b32c931aec8 Jonas Algers author c467166c-f35a-4fcf-a6eb-519167026524 Natasha Amalie Gjerløv Fiig author 69a7b8bc-4bb2-469a-ac6a-30f3d1c7ce0c Vasna Ramasar author 300b4bb6-4587-409c-bee5-bbb9948a82cf Aitzkoa Lopez de Lapuente Portilla author 29f0485c-ba7e-4ea4-9dbe-8dfe6faebc78 Jamil Khan author fcf2f9aa-bb04-4bad-baf2-e00a0d57cc93 Jenny Palm author ea885bc9-37a0-45bd-aad0-d5fe830e2951 Joakim Haraldsson author 123fb718-33b5-4f07-adee-64069c3eeb4d Mimmi Barmark author 9d6b1173-bff6-41d2-83bd-08c071be0c53 Emilie Stroh author aa8ac21b-3fec-4294-96ab-c7a632eefaa2 Helena L. Filipsson author d326ca1f-7eef-4595-bb80-6b3dc0d77319 Kerstin Sernhed author 90bc8124-e4fc-4230-b550-52b0521eb5b8 Mattias Wengelin author 9151cdb2-7ff2-490a-85dc-95ba9fa1e94a Fredric Bauer author 45837f7a-5100-4b3c-bb9a-1adccb397d54 Tomas Persson author 41523dc0-be27-4800-8a63-51feec5c39a9 Eric Brandstedt author 1d6e078e-6d44-4689-9714-f03b6609b8b1 Kes Mccormick author 4e240d04-3c4f-4b67-ac7b-919eadae9152 Wim Carton author ff339f3e-dda0-46b4-9eb9-c7211489ac2f Simon Stattin author 2be9820e-f0de-46a1-9535-ff21a4302f8a Nina Gren author c50684fe-2e8d-4a16-b936-207f8aaab366 Alexandra Nikoleris author 0825ab17-877a-4fea-8301-e5fde601986c Per Wickenberg author 66baa4ca-60e1-4fde-acf6-bc7306c2a118 Katja Garson author fe9d2b62-453e-47f2-9ce6-97ba622563ce Karin Zackari author df6902f9-cd9a-4d34-b276-0b9289305492 Nils Droste author 421398a7-7ff0-4721-b165-46cf990dba19 Mattias Gunnemyr author 0aa1678f-cde2-4e54-822b-2e96300f24a5 L-A Hansson author c5edbdbe-9cff-49c5-9da7-bd5e86b46ce1 Emelie Lantz 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cd2f8cfb-d496-4582-975f-082040447fbd Marie Larsson author f9f0445b-0e6d-4954-afb6-a35a6f559ae1 Markus Grillitsch author 9a1e4540-6a25-48a2-ae01-2f5b9ef145c8 Mariko Takedomi Karlsson author ac5cc661-0b6d-4449-9e44-5996da4b9513 Hampus Månefjord author 3511106b-285c-4700-a9b6-1d910f56302e Laura Giese author Alexander Betsholtz author b2371f84-26c7-4dfc-84d3-9f11ff4aa819 Anton Wrisberg author fa34bc05-ca31-4873-82d8-78da3764840d Marie Söderlind author 91c5624a-b0f7-4edc-a606-bc2833cc2c7d Andreas Vilhelmsson author 4784dcae-6bd6-478e-a8c3-8a847f26af5d Kristoffer Stedt author Department of Service Studies v1000682 department Dept of Physical Geography and Ecosystem Science v1000639 department Paediatrics (Lund) v1000473 department Cancerepidemiology and radiation v1001377 department LUCSUS (Lund University Centre for Sustainability Studies) v1000928 department Quaternary Sciences v1000638 department MERGE: ModElling the Regional and Global Earth system v1000618 department Civil Society and 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department NanoLund: Centre for Nanoscience v1000190 department LTH Profile Area: Circular Building Sector v1001506 department Urbanity, housing, environment v1001469 department Department of Architecture and Built Environment v1000213 department Lithosphere and Biosphere Science v1000635 department eSSENCE: The e-Science Collaboration v1001240 department Sociology v1000692 department Environmental and Energy Systems Studies v1000256 department Department of Political Science v1000693 department StemTherapy: National Initiative on Stem Cells for Regenerative Therapy v1001247 department Hematogenomics v1001108 department Division of Hematology and Clinical Immunology v1000553 department Department of Sociology v1000689 department Efficient Energy Systems v1000206 department LTH Profile Area: The Energy Transition v1001508 department Mathematics (Faculty of Engineering) v1000667 department Human Rights Studies v1000058 department Social Anthropology v1000691 department Sociology of Law 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Societal Safety v1000224 department Division of Chemical Engineering v1000243 department Temporarily employed v1000217 department EPI@BIO v1001298 department Lund University Centre for Risk Assessment and Management (LUCRAM) v1000186 department Psychiatry v1000499 department Surgery v1000516 department Ageing and Eldercare v1001312 department Evolutionary ecology v1000609 department Department of Strategic Communication v1000683 department Combustion Physics v1000625 department Child, Youth and Family v1001313 department Environmental Epidemiology v1001082 department et al. author Aquatic Ecology research group Planetary Health research group Hematogenomics research group CAnMove - Centre for Animal Movement Research research group Sustainable futures research group Plant Biology research group Christianity and Nationalism research group EPI@BIO research group Psychiatry research group Surgery research group Environmental Epidemiology research group Climate solutions project Harmonic Analysis and Applications project Metaphysics and Collectivity project 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav https://portal.research.lu.se/en/publications/faaef48c-ba98-4329-bfc7-a11fe179e069 Aftonbladet Hierta AB 2022-12-07 swe Political Science https://www.aftonbladet.se/debatt/a/pQ1qkV/1-620-forskare-och-larare-de-unga-gor-ratt-som-stammer-staten 1103-9000 faaef48c-ba98-4329-bfc7-a11fe179e069 2022-12-08T08:44:14+01:00 2026-05-26T15:42:11+02:00 2022-12-08T08:44:14+01:00 18 info:srw/schema/1/mods-v3.3xml journalArticle published yes 276 Janina S. Ried author Janina M. Jeff author Audrey Y. Chu author Jennifer L. Bragg-Gresham author Jenny Van Dongen author Jennifer E. Huffman author Tarunveer S. Ahluwalia author Gemma Cadby author Niina Eklund author Joel Eriksson author Toñu Esko author Mary F. Feitosa author Anuj Goel author Mathias Gorski author Caroline Hayward author Nancy L. Heard-Costa author Anne U. Jackson author Eero Jokinen author Stavroula Kanoni author Kati Kristiansson author 1578cf81-bff4-42b8-9d99-5d9c992c9819 Zoltán Kutalik author Jari Lahti author Jian'an Luan author Reedik Mägi author Anubha Mahajan author Massimo Mangino author Carolina Medina-Gomez author Keri L. Monda author Ilja M. Nolte author Louis Pérusse author Inga Prokopenko author Lu Qi author Lynda M. Rose author Erika Salvi author Megan T. Smith author Harold Snieder author Alena Standáková author Yun Ju Sung author Ioanna Tachmazidou author Alexander Teumer author Gudmar Thorleifsson author Pim Van Der Harst author Ryan W. Walker author Sophie R. Wang author Sarah H. Wild author Sara M. Willems author Andrew Wong author Weihua Zhang author Eva Albrecht author Alexessander Couto Alves author Stephan J L Bakker author Cristina Barlassina author Traci M. Bartz author John Beilby author Claire Bellis author Richard N. Bergman author Sven Bergmann author John Blangero author Matthias Blüher author Eric Boerwinkle author Lori L. Bonnycastle author Stefan R. Bornstein author Marcel Bruinenberg author Harry Campbell author Yii Der Ida Chen author Charleston W K Chiang author Peter S. Chines author Francis S. Collins author Fracensco Cucca author L. Adrienne Cupples author Francesca D'avila author Eco J C De Geus author George Dedoussis author Maria Dimitriou author Angela Döring author Johan G. Eriksson author f4b586e8-b660-41ea-a21a-6aefce91019e Aliki Eleni Farmaki author Martin Farrall author Teresa Ferreira author Krista Fischer author Nita G. Forouhi author Nele Friedrich author Anette Prior Gjesing author Nicola Glorioso author Mariaelisa Graff author Harald Grallert author Niels Grarup author Jürgen Gräßler author Jagvir Grewal author Anders Hamsten author Marie Neergaard Harder author Catharina A. Hartman author Maija Hassinen author Nicholas Hastie author Andrew Tym Hattersley author Aki S. Havulinna author Markku Heliövaara author Hans Hillege author Albert Hofman author Oddgeir Holmen author Georg Homuth author Jouke Jan Hottenga author Jennie Hui author Lise Lotte Husemoen author Pirro G. Hysi author Aaron Isaacs author Till Ittermann author Shapour Jalilzadeh author Alan L. James author Torben Jørgensen author Pekka Jousilahti author Antti Jula author Johanne Marie Justesen author Anne E. Justice author Mika Kähönen author Maria Karaleftheri author Kay Tee Khaw author Sirkka M. Keinanen-Kiukaanniemi author Leena Kinnunen author Paul B. Knekt author Heikki A. Koistinen author Ivana Kolcic author Ishminder K. Kooner author Seppo Koskinen author Peter Kovacs author Theodosios Kyriakou author Tomi Laitinen author Claudia Langenberg author Alexandra M. Lewin author Peter Lichtner author Cecilia M. Lindgren author d20482c1-d798-44c4-887b-7f053c578c57 Jaana Lindström author Allan Linneberg author Roberto Lorbeer author Mattias Lorentzon author Robert Luben author Valeriya Lyssenko author c046e235-1f03-4c34-96eb-8d57e603d984 Satu Männistö author Paolo Manunta author Irene Mateo Leach author Wendy L. Mcardle author Barbara Mcknight author Karen L. Mohlke author Evelin Mihailov author Lili Milani author Rebecca Mills author May E. Montasser author Andrew P. Morris author Gabriele Müller author Arthur W. Musk author Narisu Narisu author Ken K. Ong author Ben A. Oostra author Clive Osmond author Aarno Palotie author 81c374d1-89cb-460c-b312-41fdd16a31f9 James S. Pankow author Lavinia Paternoster author Brenda W. Penninx author Irene Pichler author Maria G. Pilia author Ozren Polašek author Peter P. Pramstaller author Olli T. Raitakari author Tuomo Rankinen author D. C. Rao author Nigel W. Rayner author Rasmus Ribel-Madsen author Treva K. Rice author Marcus Richards author Paul M. Ridker author Fernando Rivadeneira author Kathy A. Ryan author Serena Sanna author Mark A. Sarzynski author Salome Scholtens author Robert A. Scott author Sylvain Sebert author Lorraine Southam author Thomas Hempel Sparsø author Valgerdur Steinthorsdottir author Kathleen Stirrups author Ronald P. Stolk author Konstantin Strauch author Heather M. Stringham author Morris A. Swertz author Amy J. Swift author Anke Tönjes author Emmanouil Tsafantakis author Peter J. Van Der Most author Jana V. Van Vliet-Ostaptchouk author Liesbeth Vandenput author Erkki Vartiainen author Cristina Venturini author Niek Verweij author Jorma S. Viikari author Veronique Vitart author Marie Claude Vohl author Judith M. Vonk author Gérard Waeber author Elisabeth Widén author Gonneke Willemsen author Tom Wilsgaard author Thomas W. Winkler author Alan F. Wright author Laura M. Yerges-Armstrong author Jing Hua Zhao author M. Carola Zillikens author Dorret I. Boomsma author Claude Bouchard author John C. Chambers author Daniel I. Chasman author Daniele Cusi author Ron T. Gansevoort author Christian Gieger author Torben Hansen author Andrew A. Hicks author Frank Hu author Kristian Hveem author Marjo Riitta Jarvelin author Eero Kajantie author Jaspal S. Kooner author Diana Kuh author Johanna Kuusisto author Markku Laakso author Timo A. Lakka author Terho Lehtimäki author Andres Metspalu author Inger Njølstad author Claes Ohlsson author Albertine J. Oldehinkel author Lyle J. Palmer author Oluf Pedersen author Markus Perola author 602ecb53-5942-4a28-a736-ec9792d3e93a Annette Peters author Bruce M. Psaty author Hannu Puolijoki author Rainer Rauramaa author Igor Rudan author Veikko Salomaa author Peter E H Schwarz author Alan R. Shudiner author Jan H. Smit author Thorkild I A Sørensen author Timothy D. Spector author Kari Stefansson author Michael Stumvoll author Angelo Tremblay author Jaakko Tuomilehto author André G. Uitterlinden author Matti Uusitupa author Uwe Völker author Peter Vollenweider author Nicholas J. Wareham author Hugh Watkins author James F. Wilson author Eleftheria Zeggini author Goncalo R. Abecasis author Michael Boehnke author Ingrid B. Borecki author Panos Deloukas author Cornelia M. Van Duijn author Caroline Fox author Leif C. Groop author 63cd5965-35ec-4f4a-99c3-8f53884abc5c Iris M. Heid author David J. Hunter author Robert C. Kaplan author Mark I. Mccarthy author Kari E. North author Jeffrey R. O'connell author David Schlessinger author Unnur Thorsteinsdottir author David P. Strachan author Timothy Frayling author Joel N. Hirschhorn author Martina Müller-Nurasyid author Ruth J F Loos author Department of Health Sciences v1000411 department Translational Muscle Research v1000486 department EXODIAB: Excellence of Diabetes Research in Sweden v1001241 department EpiHealth: Epidemiology for Health v1001239 department Translational Muscle Research research group <p>Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits. We developed an approach that calculates averaged PCs (AvPCs) representing body shape derived from six anthropometric traits (body mass index, height, weight, waist and hip circumference, waist-to-hip ratio). The first four AvPCs explain &gt;99% of the variability, are heritable, and associate with cardiometabolic outcomes. We performed genome-wide association analyses for each body shape composite phenotype across 65 studies and meta-analysed summary statistics. We identify six novel loci: LEMD2 and CD47 for AvPC1, RPS6KA5/C14orf159 and GANAB for AvPC3, and ARL15 and ANP32 for AvPC4. Our findings highlight the value of using multiple traits to define complex phenotypes for discovery, which are not captured by single-trait analyses, and may shed light onto new pathways.</p> https://portal.research.lu.se/en/publications/07f751f5-3bc7-4e81-a03e-c72b40a4600c Nature Publishing Group 2016-11-23 eng Medical Genetics and Genomics (including Gene Therapy) Physiology and Anatomy 2041-1723 85000900079 27876822 000388319700001 10.1038/ncomms13357 http://dx.doi.org/10.1038/ncomms13357 7 13357 https://www.scopus.com/pages/publications/85000900079 07f751f5-3bc7-4e81-a03e-c72b40a4600c 2017-01-02T10:24:10+01:00 2026-03-23T12:10:01+01:00 2017-01-02T10:24:10+01:00 19 info:srw/schema/1/mods-v3.3xml journalArticle published yes 204 Andrew P. Morris author Benjamin F. Voight author Tanya M. Teslovich author Teresa Ferreira author Ayellet V. Segre author Valgerdur Steinthorsdottir author Rona J. Strawbridge author Hassan Khan author Harald Grallert author Anubha Mahajan author Inga Prokopenko author Hyun Min Kang author Christian Dina author Tonu Esko author Ross M. Fraser author Stavroula Kanoni author Ashish Kumar author Vasiliki Lagou author Claudia Langenberg author Jian'an Luan author Cecilia M. Lindgren author Martina Mueller-Nurasyid author Sonali Pechlivanis author N. William Rayner author Laura J. Scott author Steven Wiltshire author Loic Yengo author Leena Kinnunen author Elizabeth J. Rossin author Soumya Raychaudhuri author Andrew D. Johnson author Antigone S. Dimas author Ruth J. F. Loos author Sailaja Vedantam author Han Chen author Jose C. Florez author Caroline Fox author Ching-Ti Liu author Denis Rybin author David J. Couper author Wen Hong L. Kao author Man Li author Marilyn C. Cornelis author Peter Kraft author Qi Sun author Rob M. van Dam author Heather M. Stringham author Peter S. Chines author Krista Fischer author Pierre Fontanillas author Oddgeir L. Holmen author Sarah E. Hunt author Anne U. Jackson author Augustine Kong author Robert Lawrence author Julia Meyer author John R. B. Perry author Carl G. P. Platou author Simon Potter author Emil Rehnberg author Neil Robertson author Suthesh Sivapalaratnam author Alena Stancakova author Kathleen Stirrups author Gudmar Thorleifsson author Emmi Tikkanen author Andrew R. Wood author Peter Almgren author 84eb2a92-237d-4e05-af64-cc15d0d8f416 Mustafa Atalay author Rafn Benediktsson author Lori L. Bonnycastle author Noel Burtt author Jason Carey author Guillaume Charpentier author Andrew T. Crenshaw author Alex S. F. Doney author Mozhgan Dorkhan author 6c7eb08b-d5d1-433a-b41c-5cc93f49ca3c Sarah Edkins author Valur Emilsson author Elodie Eury author Tom Forsen author Karl Gertow author Bruna Gigante author George B. Grant author Christopher J. Groves author Candace Guiducci author Christian Herder author Astradur B. Hreidarsson author Jennie Hui author Alan James author Anna Jonsson author 1a3749aa-fd21-455c-b76d-b44c06e08aab Wolfgang Rathmann author Norman Klopp author Jasmina Kravic author ef01911b-db9b-4b0a-a9c1-1aee54bc4c24 Kaarel Krjutskov author Cordelia Langford author Karin Leander author Eero Lindholm author db66066c-1da3-49af-8285-7f476e0379b1 Stephane Lobbens author Satu Mannisto author Ghazala Mirza author Thomas W. Muehleisen author Bill Musk author Melissa Parkin author Loukianos Rallidis author Jouko Saramies author Bengt Sennblad author Sonia Shah author Gunnar Sigurdsson author Angela Silveira author Gerald Steinbach author Barbara Thorand author Joseph Trakalo author Fabrizio Veglia author Roman Wennauer author Wendy Winckler author Delilah Zabaneh author Harry Campbell author Cornelia van Duijn author Andre G. Uitterlinden author Albert Hofman author Eric Sijbrands author Goncalo R. Abecasis author Katharine R. Owen author Eleftheria Zeggini author Mieke D. Trip author Nita G. Forouhi author Ann-Christine Syvanen author Johan G. Eriksson author Leena Peltonen author Markus M. Noethen author Beverley Balkau author Colin N. A. Palmer author Valeriya Lyssenko author c046e235-1f03-4c34-96eb-8d57e603d984 Tiinamaija Tuomi author Bo Isomaa author David J. Hunter author Lu Qi author Alan R. Shuldiner author Michael Roden author Ines Barroso author Tom Wilsgaard author John Beilby author Kees Hovingh author Jackie F. Price author James F. Wilson author Rainer Rauramaa author Timo A. Lakka author Lars Lind author George Dedoussis author Inger Njolstad author Nancy L. Pedersen author Kay-Tee Khaw author Nicholas J. Wareham author Sirkka M. Keinanen-Kiukaanniemi author Timo E. Saaristo author Eeva Korpi-Hyovalti author Juha Saltevo author Markku Laakso author Johanna Kuusisto author Andres Metspalu author Francis S. Collins author Karen L. Mohlke author Richard N. Bergman author Jaakko Tuomilehto author Bernhard O. Boehm author Christian Gieger author Kristian Hveem author Stephane Cauchi author Philippe Froguel author Damiano Baldassarre author Elena Tremoli author Steve E. Humphries author Danish Saleheen author John Danesh author Erik Ingelsson author Samuli Ripatti author Veikko Salomaa author Raimund Erbel author Karl-Heinz Joeckel author Susanne Moebus author Annette Peters author Thomas Illig author Ulf de Faire author Anders Hamsten author Andrew D. Morris author Peter J. Donnelly author Timothy M. Frayling author Andrew T. Hattersley author Eric Boerwinkle author Olle Melander author 708de71a-2d3c-4937-92fc-7768da5dab4c Sekar Kathiresan author Peter Nilsson author d4f81cfb-cf32-492f-991f-f84f66734b69 Panos Deloukas author Unnur Thorsteinsdottir author Leif Groop author 63cd5965-35ec-4f4a-99c3-8f53884abc5c Kari Stefansson author Frank Hu author James S. Pankow author Josee Dupuis author James B. Meigs author David Altshuler author Michael Boehnke author Mark I. McCarthy author Translational Muscle Research v1000486 department Cardiovascular Research - Hypertension v1000523 department Internal Medicine - Epidemiology v1000520 department EXODIAB: Excellence of Diabetes Research in Sweden v1001241 department EpiHealth: Epidemiology for Health v1001239 department Translational Muscle Research research group Cardiovascular Research - Hypertension research group Internal Medicine - Epidemiology research group To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent. We identified ten previously unreported T2D susceptibility loci, including two showing sex-differentiated association. Genomewide analyses of these data are consistent with a long tail of additional common variant loci explaining much of the variation in susceptibility to T2D. Exploration of the enlarged set of susceptibility loci implicates several processes, including CREBBP-related transcription, adipocytokine signaling and cell cycle regulation, in diabetes pathogenesis. https://portal.research.lu.se/en/publications/b8fc18e7-0d89-439a-a0b3-792ec43d5bd6 Nature Publishing Group 2012 eng Endocrinology and Diabetes Other Clinical Medicine Cardiology and Cardiovascular Disease 1546-1718 3139300 000308491200009 84868337361 22885922 10.1038/ng.2383 http://dx.doi.org/10.1038/ng.2383 yes 44 9 981 981 https://www.scopus.com/pages/publications/84868337361 b8fc18e7-0d89-439a-a0b3-792ec43d5bd6 2016-04-01T13:50:41+02:00 2025-10-14T10:31:35+02:00 2016-04-01T13:50:41+02:00 20 1.1author all "eriksson bergman"authoralleriksson bergman