1.1 287828 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 Ali Mohammad Bagher author 5bbd2eae-c43a-440d-9419-0f847c35aacb Lina Andersson author Carl Johan Wingren author cdc7e2d1-a7e4-4a1f-86a8-85487f1397ab Anders Ottosson author a946b9fa-fb58-4296-bab2-a04ae9f6dc54 Sakarias Wangefjord author 92dfa871-1c04-42e4-a17c-60ded636d69c Stefan Acosta author 3c7913bd-3508-460f-a091-8defb00eefe6 Surgery v1000516 department Forensic Medicine v1000543 department Tumor microenvironment v1000471 department Vascular Diseases - Clinical Research v1000518 department EpiHealth: Epidemiology for Health v1001239 department Surgery research group Forensic Medicine research group Vascular Diseases - Clinical Research research group We applied the new injury severity scoring system and studied mechanisms of injury and risk factors for mortality, in order to find potential preventive measures, in the present Scandinavian trauma cohort triaged through red trauma alarm according to the Medical Emergency Triage and Treatment System. https://portal.research.lu.se/en/publications/16a3b263-dd0a-4284-9494-ef315495b691 SAGE Publications 2015 eng Health Sciences http://www.ncbi.nlm.nih.gov/pubmed/25816859?dopt=Abstract yes 1651-1905 5257509 25816859 000357581300009 84936998829 25816859 10.1177/1403494815578322 http://dx.doi.org/10.1177/1403494815578322 yes 43 5 506 513 https://www.scopus.com/pages/publications/84936998829 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit for Clinical Vascular Disease Research (013242410), Surgery Research Unit (013242220), Pathology, (Lund) (013030000), Forensic medicine (013240050) 16a3b263-dd0a-4284-9494-ef315495b691 2016-04-01T09:47:25+02:00 2025-10-14T13:02:44+02:00 2016-04-01T09:47:25+02:00 1 info:srw/schema/1/mods-v3.3xml journalArticle published yes 4 Sara Sjalander author Anders Sjalander author Peter Svensson author 9beb5ebe-3809-43d2-9688-81a0ea56cfe9 Leif Friberg author Clinical Coagulation, Malmö v1000575 department Clinical Coagulation, Malmö research group Oral anticoagulation is the recommended treatment for stroke prevention in patients with atrial fibrillation. Notwithstanding, many patients are treated with acetylsalicylic acid (ASA) as monotherapy. Our objective was to investigate if atrial fibrillation patients benefit from ASA as monotherapy for stroke prevention. Retrospective study of patients with a clinical diagnosis of atrial fibrillation between 1 July 2005 and 1 January 2009 in the National Swedish Patient register, matched with data from the National Prescribed Drugs register. Endpoints were ischaemic stroke, thrombo-embolic event, intracranial haemorrhage, and major bleeding. The study population consisted of 115 185 patients with atrial fibrillation, of whom 58 671 were treated with ASA as monotherapy and 56 514 were without any antithrombotic treatment at baseline. Mean follow-up was 1.5 years. Treatment with ASA was associated with higher risk of ischaemic stroke and thrombo-embolic events compared with no antithrombotic treatment. Acetylsalicylic acid as monotherapy in stroke prevention of atrial fibrillation has no discernable protective effect against stroke, and may even increase the risk of ischaemic stroke in elderly patients. Thus, our data support the new European guidelines recommendation that ASA as monotherapy should not be used as stroke prevention in atrial fibrillation. https://portal.research.lu.se/en/publications/8b3d85a0-4847-420b-90c3-86c1e0a65f26 Oxford University Press 2014 eng Atrial fibrillation Stroke Acetylsalicylic acid Cardiology and Cardiovascular Disease 1532-2092 4559114 000336080400006 84900330073 24158253 10.1093/europace/eut333 http://dx.doi.org/10.1093/europace/eut333 16 5 631 638 https://www.scopus.com/pages/publications/84900330073 8b3d85a0-4847-420b-90c3-86c1e0a65f26 2016-04-01T09:47:25+02:00 2025-10-14T09:06:35+02:00 2016-04-01T09:47:25+02:00 2 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 Carl-Erik Flodmark author db29163e-0cc0-480a-aaa4-46132a9dde34 W Shen author M Punyanitya author Peter Leander author 623ec022-5bd7-409f-aec0-43fbd2339332 J Lanke author A Pietrobelli author Preventive Paediatrics v1000537 department Radiology Diagnostics, Malmö v1000580 department Preventive Paediatrics research group Radiology Diagnostics, Malmö research group What is already known about this subject Sagittal diameter (SAD), i.e. the mid height of the abdomen when lying down, has been reported to correlate to visceral fat, insulin resistance and cardiovascular risk factors in adults. SAD seems to be the best anthropometric predictor of cardiovascular risk, and also of more importance than waist circumference (WC) in adults. There has been no validation studies comparing SAD measured with anthropometric tools (e.g. ruler) to measurements made with more exact devices such as magnetic resonance imaging (MRI) in pediatric age. What this study adds This new reliable method is ideal for children due to limited body contact and no radiation. It is accurate, less expensive than MRI, and also easier to perform than measuring WC. It is easily available for screening purposes making future epidemiological studies possible evaluating health risks related to regional distribution of abdominal tissue. OBJECTIVES: Sagittal diameter (SAD) has been reported to correlate to visceral fat and cardiovascular risk factors. SAD is measured with the individual lying down, halfway between the lower rib margin and the iliac crest; it represents the mid-height of the abdomen. The aim of this study was to validate SAD measured using a recently-developed laser beam device (SAD(LDB) ) against SAD measured using MRI (SAD(MRI) ). METHODS: Of 48 obese children (25 boys, 23 girls) aged 9-11 years on the waiting list for obesity treatment, 34 agreed to a baseline measurement, which was followed by repeated measurements 6 and 12 months later in 31 and 22 children respectively. MRI was used to examine SAD(MRI) at 5 cm above (SAD(MRI) (,cra) ) and below (SAD(MRI) (,cau) ) the mid plane of the L4-5 intervertebral disc. RESULTS: Each of the differences SAD(LBD) - SAD(MRI) (,cau) and SAD(LBD) - SAD(MRI) (,cra) was subjected to a repeated-measurements ANOVA; the visit did not have a statistically significant effect in either case (p = 0.19 and p = 0.72, respectively). The difference SAD(LBD) - SAD(MRI) (,cau) was 1.50 on average (p &lt; 0.0001; CI 1.26-1.74) while the corresponding figure for SAD(LBD) - SAD(MRI) (,cra) was 1.26 (p &lt; 0.0001; CI 1.04-1.49). Regression of the difference on the mean gave slopes of -0.09 (p = 0.25) and -0.04 (p = 0.57) respectively. Prediction of SAD(MRI) from SAD(LDB) can be performed in different ways: by means of linear regression or by means of an additive correction. CONCLUSIONS: Thus, this laser device can be used instead of MRI to estimate SAD by using a simple correction. https://portal.research.lu.se/en/publications/53f90112-b5c4-4119-b6fa-1ea4aac065f3 Wiley-Blackwell 2013 eng Pediatrics http://www.ncbi.nlm.nih.gov/pubmed/23002010?dopt=Abstract yes 2047-6310 3123700 000316328400006 23002010 84878350618 23002010 10.1111/j.2047-6310.2012.00095.x http://dx.doi.org/10.1111/j.2047-6310.2012.00095.x yes 8 2 112 117 https://www.scopus.com/pages/publications/84878350618 53f90112-b5c4-4119-b6fa-1ea4aac065f3 2016-04-01T09:47:25+02:00 2025-10-14T09:31:55+02:00 2016-04-01T09:47:25+02:00 3 info:srw/schema/1/mods-v3.3xml journalArticle published yes 9 Anders Bergqvist author 8ea5e29f-0584-48e3-aff5-ddf5389490a0 Cecilia K Andersson author 6c8b91f1-2a5e-4df3-b389-6a51b2d6bf48 Hans-Jürgen Hoffmann author Michiko Mori author bf4dc1c2-1515-4e2d-8d49-0fec9c809de0 Medya Shikhagaie author 778e6cdb-dff6-4e93-9665-ee0b4e94c2a7 Inge Kortekaas Krohn author Ronald Dahl author Leif Bjermer author 14f9431b-d68a-4ad5-8d0f-d70144c43c56 Jonas Erjefält author 5c60a25d-92d9-45a5-9da3-696db9eed111 EpiHealth: Epidemiology for Health v1001239 department Airway Inflammation and Immunology v1000378 department Respiratory Medicine, Allergology, and Palliative Medicine v1000434 department Airway Inflammation and Immunology research group https://portal.research.lu.se/en/publications/c93c6272-3270-4812-b678-1dad5bce96ff American Thoracic Society 2013 eng Respiratory Medicine and Allergy http://www.ncbi.nlm.nih.gov/pubmed/24328780?dopt=Abstract yes 1535-4970 4224860 000328260700026 24328780 84890521552 24328780 10.1164/rccm.201308-1444LE http://dx.doi.org/10.1164/rccm.201308-1444LE yes 188 12 1475 1477 https://www.scopus.com/pages/publications/84890521552 c93c6272-3270-4812-b678-1dad5bce96ff 2016-04-01T09:47:26+02:00 2025-10-14T13:21:55+02:00 2016-04-01T09:47:26+02:00 4 info:srw/schema/1/mods-v3.3xml journalArticle published yes 10 Jialei Ye author Junxian Yun author Dong-Qiang Lin author Linhong Xu author Harald Kirsebom author 1961e7e8-a622-4459-9a22-37aeeb76bce4 Shaochuan Shen author Gensheng Yang author Kejian Yao author Yi-Xin Guan author Shan-Jing Yao author Biotechnology v1000653 department A novel super-macroporous monolithic composite cryogel was prepared by embedding macroporous cellulose beads into poly(hydroxyethyl methacrylate) cryogel. The cellulose beads were fabricated by using a microchannel liquid-flow focusing and cryopolymerization method, while the composite cryogel was prepared by cryogenic radical polymerization of the hydroxyethyl methacrylate monomer with poly(ethylene glycol) diacrylate as cross-linker together with the cellulose beads. After graft polymerization with (vinylbenzyl)trimethylammonium chloride, the composite cryogel was applied to separate immunoglobulin-G and albumin from human serum. Immunoglobulin-G with a mean purity of 83.2% and albumin with a purity of 98% were obtained, indicating the composite cryogel as a promising chromatographic medium in bioseparation for the isolation of important bioactive proteins like immunoglobulins and albumins. https://portal.research.lu.se/en/publications/9f931a1f-490a-4244-a7a9-78d6c7791e85 John Wiley & Sons Inc. 2013 eng Bioseparation Cellulose beads Cryogels Immunoglobulin-G Ion-exchange adsorption Industrial Biotechnology 1615-9314 4269100 000328138200001 84890461139 24151195 10.1002/jssc.201300911 http://dx.doi.org/10.1002/jssc.201300911 yes 36 24 3813 3820 https://www.scopus.com/pages/publications/84890461139 9f931a1f-490a-4244-a7a9-78d6c7791e85 2016-04-01T09:47:26+02:00 2025-10-14T10:48:20+02:00 2016-04-01T09:47:26+02:00 5 info:srw/schema/1/mods-v3.3xml journalArticle published yes 5 Peter Fritzell author Bjorn Knutsson author Bengt Sanden author Björn Strömqvist author 88e23d50-8f3c-4907-92aa-9f636684863a Olle Hagg author Orthopaedics (Lund) v1000443 department Lumbar disc herniation (LDH) is a common indication for lumbar spine surgery. The proportion of patients having a second surgery within 2 years varies in the literature between 0.5% and 24%, with recurrent herniation being the most common cause. Several studies have not found any relevant outcome differences between patients undergoing surgery for primary LDH and patients undergoing reoperation for a recurrent LDH, but these studies have limitations, including small sample size and retrospective design. We (1) compared patient-reported outcomes between patients operated on for primary LDH and patients reoperated on for recurrent LDH within 1 year after index surgery and (2) determined risk factors for worse outcomes. We obtained data from the Swedish National Spine Register, Swespine, where patient-reported outcomes are collected using mailed protocols at 1, 2, 5, and 10 years after surgery. Of the 13,562 patients identified who underwent LDH between January 2000 and May 2011, 13,305 (98%) underwent primary surgery for LDH and 257 (2%) underwent reoperation for a recurrent LDH within the first year. Patient-reported outcomes at 1 to 2 years were available for 8497 patients (63%), 8350 of 13,305 (63%) in the primary LDH group and 147 of 257 (57%) in the recurrent LDH group (p = 0.068). We compared leg and back pain (VAS: 0-100), function (Oswestry Disability Index [ODI]: 0-100), quality of life (EQ-5D: -0.59 to 1.0), patient satisfaction, and global assessment of leg pain between groups. We also analyzed rsik factors for worse global assessment and satisfaction. Mean (95% CI) differences in improvement between groups favoring patients with primary LDH were VAS leg pain 9 (4-14), ODI 6 (3-9), and EQ-5D 0.09 (0.04-0.15). While statistically significant, these effect sizes may be lower than the minimal clinically important differences often referred to. Percentage of satisfied patients was 79% and 58% in the primary and recurrent LDH groups, respectively (p &lt; 0.001), and percentage of patients with no or better leg pain (global assessment) was 74% and 65%, respectively (p = 0.008). Reoperation for recurrent LDH represented the largest independent risk for dissatisfaction; this factor and smoking represented similar risks for less improvement in leg pain. Repeat surgery for a recurrent LDH was performed with good probability for improvement, although not as good as for primary LDH surgery, and patients undergoing repeated surgery were less satisfied. Studies on risk factors for recurrence are warranted. Level II, therapeutic study. See Instructions for Authors for a complete description of levels of evidence. https://portal.research.lu.se/en/publications/24e5c0e3-731d-40e6-acbc-c99b6c92e937 https://portal.research.lu.se/files/1245063/8563952 application/pdf 651882 no Wolters Kluwer Health Inc 2015 eng Orthopaedics 0009-921X 7424998 000354133000018 84897359941 24711131 10.1007/s11999-014-3596-8 http://dx.doi.org/10.1007/s11999-014-3596-8 473 6 1978 1984 https://www.scopus.com/pages/publications/84897359941 24e5c0e3-731d-40e6-acbc-c99b6c92e937 2016-04-01T09:47:27+02:00 2025-10-14T10:35:06+02:00 2016-04-01T09:47:27+02:00 6 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Maysam Behravesh author b4265f79-745a-48a9-b64a-391900ea507f This article is a largely constructivist revisit to the crisis of confidence between Iran and the West. It strives to investigate the chief historical, cultural, ideological, and identity-related, as well as geostrategic factors, involved in postrevolutionary Iran-West relations, and how they have caused an almost solidified sense of fear, suspicion, and mistrust between the two. The contemporary major areas of conflict the study delineates are (a) the human rights issue, (b) Iran's nuclear program, (c) Iranian-Israeli hostility, and (d) the U.S.-led wars in Afghanistan and Iraq. The article concludes that the restoration of mutual confidence requires a structural overhaul of both sides' ideological attitudes and political practices toward each other. https://portal.research.lu.se/en/publications/0be4e2a0-f4a9-4a26-a541-d7bada37a4b8 https://portal.research.lu.se/files/1245090/4436952.pdf application/pdf 158138 no Wiley-Blackwell 2011 eng Iran identity crisis constructivism West Political Science http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1943-0787 yes 1943-0787 3051071 80055005140 10.1111/j.1943-0787.2011.01274.x http://dx.doi.org/10.1111/j.1943-0787.2011.01274.x yes 3 3 327 347 https://www.scopus.com/pages/publications/80055005140 yes 0be4e2a0-f4a9-4a26-a541-d7bada37a4b8 2016-04-01T09:47:27+02:00 2025-10-14T12:47:13+02:00 2016-04-01T09:47:27+02:00 7 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 T. Hauffe author C. Albrecht author K. Schreiber author Klaus Birkhofer author 5a137dc4-199f-4279-bd50-63e04fa4750a S. Trajanovski author T. Wilke author Biodiversity v1000603 department The quality of spatial analyses of biodiversity is improved by (i) utilizing study areas with well defined physiogeographical boundaries, (ii) limiting the impact of widespread species, and (iii) using taxa with heterogeneous distributions. These conditions are typically met by ecosystems such as oceanic islands or ancient lakes and their biota. While research on ancient lakes has contributed significantly to our understanding of evolutionary processes, statistically sound studies of spatial variation of extant biodiversity have been hampered by the frequently vast size of ancient lakes, their limited accessibility, and the lack of scientific infrastructure. The European ancient Lake Ohrid provides a rare opportunity for such a reliable spatial study. The comprehensive horizontal and vertical sampling of a species-rich taxon, the Gastropoda, presented here, revealed interesting patterns of biodiversity, which, in part, have not been shown before for other ancient lakes. <br/><br> <br/><br> In a total of 284 samples from 224 different locations throughout the Ohrid Basin, 68 gastropod species, with 50 of them (= 73.5%) being endemic, could be reported. The spatial distribution of these species shows the following characteristics: (i) within Lake Ohrid, the most frequent species are endemic taxa with a wide depth range, (ii) widespread species (i.e. those occurring throughout the Balkans or beyond) are rare and mainly occur in the upper layer of the lake, (iii) while the total number of species decreases with water depth, the proportion of endemics increases, and (iv) the deeper layers of Lake Ohrid appear to have a higher spatial homogeneity of biodiversity. Moreover, gastropod communities of Lake Ohrid and its feeder springs are both distinct from each other and from the surrounding waters. The analysis also shows that community similarity of Lake Ohrid is mainly driven by niche processes (e.g. environmental factors), but also by neutral processes (e.g. dispersal limitation and evolutionary histories of species). For niche-based mechanisms it is shown that large scale effects such as type of water body or water depth are mainly responsible for the similarity of gastropod communities, whereas small scale effects like environmental gradients affect gastropod compositions only marginally. In fact, neutral processes appear to be more important than the small scale environmental factors, thus emphasizing the importance of dispersal capacities and evolutionary histories of species. https://portal.research.lu.se/en/publications/68c933ce-3bde-4881-8196-4052abc8b6ab Copernicus GmbH 2011 eng Ecology (including Biodiversity Conservation) http://www.scopus.com/inward/record.url?eid=2-s2.0-79551501734&partnerID=40&md5=096b7077b2b870e3823b1332ec9d151a 1726-4189 2440409 79551501734 10.5194/bg-8-175-2011 http://dx.doi.org/10.5194/bg-8-175-2011 yes 8 1 175 188 https://www.scopus.com/pages/publications/79551501734 68c933ce-3bde-4881-8196-4052abc8b6ab 2016-04-01T09:47:27+02:00 2025-10-14T09:23:45+02:00 2016-04-01T09:47:27+02:00 8 info:srw/schema/1/mods-v3.3xml journalArticle published yes 22 Oliver Schweiger author Jacobus C. Biesmeijer author Riccardo Bommarco author Thomas Hickler author fb05def1-885d-4ada-9049-cf7ee09ead83 Philip E. Hulme author Stefan Klotz author Ingolf Kuehn author Mari Moora author Anders Nielsen author Ralf Ohlemueller author Theodora Petanidou author Simon G. Potts author Petr Pysek author Jane C. Stout author Martin Sykes author c8bad4f7-8e3b-4a2d-a396-aca1546d68d5 Thomas Tscheulin author Montserrat Vila author Gian-Reto Walther author Catrin Westphal author Marten Winter author Martin Zobel author Josef Settele author Dept of Physical Geography and Ecosystem Science v1000639 department BECC: Biodiversity and Ecosystem services in a Changing Climate v1000616 department Global change may substantially affect biodiversity and ecosystem functioning but little is known about its effects on essential biotic interactions. Since different environmental drivers rarely act in isolation it is important to consider interactive effects. Here, we focus on how two key drivers of anthropogenic environmental change, climate change and the introduction of alien species, affect plant-pollinator interactions. Based on a literature survey we identify climatically sensitive aspects of species interactions, assess potential effects of climate change on these mechanisms, and derive hypotheses that may form the basis of future research. We find that both climate change and alien species will ultimately lead to the creation of novel communities. In these communities certain interactions may no longer occur while there will also be potential for the emergence of new relationships. Alien species can both partly compensate for the often negative effects of climate change but also amplify them in some cases. Since potential positive effects are often restricted to generalist interactions among species, climate change and alien species in combination can result in significant threats to more specialist interactions involving native species. https://portal.research.lu.se/en/publications/8f148265-a381-4ac5-87c0-59f29bfc08a4 John Wiley & Sons Inc. 2010 eng higher order effects global change services ecosystem ecosystem functions biological invasions competition species interactions pollination multiple drivers Physical Geography 1469-185X 1721130 000282880900005 77954804802 20184567 10.1111/j.1469-185X.2010.00125.x http://dx.doi.org/10.1111/j.1469-185X.2010.00125.x yes 85 4 777 795 https://www.scopus.com/pages/publications/77954804802 8f148265-a381-4ac5-87c0-59f29bfc08a4 2016-04-01T09:47:27+02:00 2026-03-11T12:05:00+01:00 2016-04-01T09:47:27+02:00 9 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Petter Hedelin author David Kylhammar author f4d836d1-d68a-4add-9960-74bd7ed5c39d Göran Rådegran author e8a0258c-89c0-41f0-bdf1-64feb1ea74be Cardiology v1000432 department Aim: Our aim was to test the hypothesis that dual endothelin receptor blockade with tezosentan attenuates hypoxia induced pulmonary vasoconstriction. Methods: 14 anaesthetised, ventilated pigs, with a mean±SEM weight of 30,5±0,6 kg, were studied, in normoxia (FiO(2) â0,21) and with tezosentan (5mg·kg(-1) ) infusion during (n=7) or before (n=7) hypoxia (FiO(2) ∼0,10). Results: Compared to normoxia, hypoxia, increased (p&lt;0,05) pulmonary vascular resistance by 3,4±0,7 WU, mean pulmonary artery pressure by 13,7±1,3 mmHg, mean right atrial pressure by 1,9±0,4 mmHg and decreased (p&lt;0,02) systemic vascular resistance by 5,2±2,1 WU. Pulmonary capillary wedge pressure, mean aortic blood pressure, heart rate, cardiac output, stroke volume and blood-O(2) -consumption were unaltered (p=ns). Tezosentan infused during hypoxia, normalised pulmonary vascular resistance, decreased (p&lt;0,05) maximally mean pulmonary artery pressure by 7,5±0,8 mmHg, systemic vascular resistance by 5,8±0,7 WU, mean aortic blood pressure by 10,8±3,0 mmHg and increased (p&lt;0,04) stroke volume by 8,5±1,8 mL. Mean right atrial pressure, pulmonary capillary wedge pressure, heart rate, cardiac output and blood-O(2) -consumption were unaltered (p=ns). Tezosentan infused before hypoxia additionally attenuated ∼70% of the initial mean pulmonary artery pressure increase and abolished the pulmonary vascular resistance increase, without additionally affecting the other parameters. Conclusion: Dual endothelin receptor blockade during hypoxia, attenuates the "sustained" acute pulmonary vasoconstrictor response by reducing the mean pulmonary artery pressure increase by ∼62% and by normalising pulmonary vascular resistance. Pre-treatment with tezosentan before hypoxia, additionally attenuates the initial hypoxia induced mean pulmonary artery pressure rise by ∼70% and abolishes the pulmonary vascular resistance increase, during stable circulatory conditions, without affecting oxygenation. https://portal.research.lu.se/en/publications/f367bee9-b978-4ee9-b292-8dabe4070f34 Wiley-Blackwell 2012 eng hypoxic pulmonary vasoconstriction pulmonary hypertension vascular tone pulmonary Physiology and Anatomy http://www.ncbi.nlm.nih.gov/pubmed/21726419?dopt=Abstract yes 1748-1708 2059018 000299775100014 21726419 84856557478 21726419 10.1111/j.1748-1716.2011.02339.x http://dx.doi.org/10.1111/j.1748-1716.2011.02339.x yes 204 3 419 434 https://www.scopus.com/pages/publications/84856557478 f367bee9-b978-4ee9-b292-8dabe4070f34 2016-04-01T09:47:28+02:00 2025-10-14T10:47:10+02:00 2016-04-01T09:47:28+02:00 10 info:srw/schema/1/mods-v3.3xml journalArticle published yes 7 Wenxian Li author Zhan Shi author Yang Yang author Jun Xiao author Tomas Brage author fffe21c2-5ec5-4333-b257-5c36c0036643 Roger Hutton author Yaming Zou author Department of Physics v1000621 department We have recorded extreme ultraviolet spectra from W11+ to W15+ ions using a flat-field spectrometer installed at the Shanghai high-temperature superconducting electron-beam ion trap. The spectra were recorded at beam energies ranging between 200 and 400 eV and showed spectral lines and transition arrays in the 170-260 angstrom region. The charge states and spectra transitions were identified by comparison with calculations using a detailed relativistic configuration interaction method and collisional-radiative model, both incorporated in the flexible atomic code. Atomic structure calculations showed that the dominant emission arises from 5d --&gt; 5p and 5p --&gt; 5s transitions. The work also identified the ground-state configuration of W13+ as 4f(13)5s(2) both theoretically and experimentally. https://portal.research.lu.se/en/publications/ff7a3a73-f8d7-4bee-b258-0213d4aea7ef American Physical Society 2015 eng Atom and Molecular Physics and Optics 1050-2947 7410506 000355409200004 84937437706 10.1103/PhysRevA.91.062501 http://dx.doi.org/10.1103/PhysRevA.91.062501 yes 91 6 062501 https://www.scopus.com/pages/publications/84937437706 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Physics, science (011013100) ff7a3a73-f8d7-4bee-b258-0213d4aea7ef 2016-04-01T09:47:28+02:00 2025-10-14T08:57:04+02:00 2016-04-01T09:47:28+02:00 11 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Maria Stanfors author 8ebc49b1-19ef-4df3-9880-57e22ce97a3a Cecilia Larsson author 63154e0d-ba88-47f2-9dff-044ff70fcfd3 Centre for Economic Demography v1000018 department Department of Economic History v1000022 department Fertility remains higher and contraceptive levels are substantially lower in Sub-Saharan Africa than elsewhere in the developing world. In this paper we use information on individuals and couples provided in recent Demographic and Health Surveys (DHS, fifth wave) undertaken in Ghana, Kenya, Madagascar, and Zambia. We use bivariate and multivariate techniques to examine the determinants of contraceptive use among married women (aged 15-49), focusing on the impacts of women’s education and empowerment. Our results show that education was an important determinant of contraceptive use, but mattered less in choice of method effectiveness. The impact of education was similar in all the countries studied with the exception of Kenya, where it was non-existent. Empowerment was less important in determining contraceptive use. Efforts to increase contraceptive use in general and the use of modern methods more specifically need to focus on providing basic education for all women and on changing gender roles. https://portal.research.lu.se/en/publications/644e0eb6-f9f9-4ea4-9175-77f3311efeab Union for African Population Studies 2014 eng Education empowerment contraceptive use logit regression Sub-Saharan Africa Economic History 2308-7854 4857161 84915793159 10.11564/28-0-554 http://dx.doi.org/10.11564/28-0-554 28 2 1022 1034 https://www.scopus.com/pages/publications/84915793159 644e0eb6-f9f9-4ea4-9175-77f3311efeab 2016-04-01T09:47:29+02:00 2025-10-14T12:13:18+02:00 2016-04-01T09:47:29+02:00 12 info:srw/schema/1/mods-v3.3xml conference abstract published yes 10 M. D. Crema author F. W. Roemer author Martin Englund author 2c658f78-242d-4d93-a44e-4e23d5928ec4 K. Wang author D. T. Felson author M. C. Nevitt author M. D. Marra author J. Tomer author C. E. Lewis author A. Guermazi author Orthopaedics (Lund) v1000443 department EpiHealth: Epidemiology for Health v1001239 department World Congress of the OsteoArthritis-Research-Society-International https://portal.research.lu.se/en/publications/ed93804e-dbc8-456d-a829-98a3495e9e6d W.B. Saunders 2010 2010-09-23 - 2010-09-26 eng Clinical Medicine 1063-4584 1771128 000283452900422 74149084373 18 175 176 https://www.scopus.com/pages/publications/74149084373 ed93804e-dbc8-456d-a829-98a3495e9e6d 2016-04-01T09:47:29+02:00 2025-10-14T13:21:24+02:00 2016-04-01T09:47:29+02:00 13 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Johan Ruben Gustafsson author 246b3fe3-9af0-49c6-ac5c-f29253aaeda5 Per Nilsson author 9d75549c-2fe9-4d87-84f4-cda58255b8ac Katarina Sjögreen Gleisner author b5daefb9-3353-49f3-adba-d5a97b7e7a5f Medical Radiation Physics, Lund v1000468 department We have previously shown analytically that the biologically effective dose (BED), including effects of repair during irradiation and of incomplete repair between fractions, can be formulated using a convolution between the absorbed dose rate function and the function describing repair. In this work, a discrete formalism is derived along with its implementation via the fast Fourier transform. The implementation takes the intrinsic periodicity of the discrete Fourier transform into consideration, as well as possible inconsistencies that may arise due to discretization and truncation of the functions describing the absorbed dose rate and repair. Numerically and analytically calculated BED values are compared for various situations in external beam radiotherapy, brachytherapy and radionuclide therapy, including the use of different repair models. The numerical method is shown to be accurate and versatile since it can be applied to any kind of absorbed dose rate function and allows for the incorporation of different repair models. Typical accuracies for clinically realistic examples are in the order of 10(-3)% to 10(-5)%. The method has thus the potential of being a useful tool for the calculation of BED, also in situations with complicated irradiation patterns or repair functions. https://portal.research.lu.se/en/publications/7333d106-f769-4071-a8bc-5506cf70b534 IOP Publishing 2013 eng Radiology and Medical Imaging http://www.ncbi.nlm.nih.gov/pubmed/23406832?dopt=Abstract yes 1361-6560 3559831 000315191400023 23406832 84880948891 23406832 10.1088/0031-9155/58/5/1529 http://dx.doi.org/10.1088/0031-9155/58/5/1529 yes 58 5 1529 1548 https://www.scopus.com/pages/publications/84880948891 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Reconstructive Surgery (013240300) 7333d106-f769-4071-a8bc-5506cf70b534 2016-04-01T09:47:29+02:00 2026-01-14T04:27:45+01:00 2016-04-01T09:47:29+02:00 14 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Gilberto Colangelo author Andreas Fuhrer author Stefan Lanz author 75bd0a91-38f9-4b3a-bbf7-54915dea7544 Theoretical Particle Physics v1000645 department We apply the resummed version of the Luscher formula to analyze finite volume corrections to the mass of the nucleon and of heavy mesons. We show that by applying the subthreshold expansion of the scattering amplitudes one can express the finite volume corrections in terms of only a few physical observables and the size of the box. In the case of the nucleon, the available information about the quark mass dependence of these physical quantities is discussed and used to assess the finite volume corrections to the nucleon mass as a function of the quark mass including a detailed analysis of the remaining uncertainties. For heavy mesons, the Luscher formula is derived both fully relativistically and in a nonrelativistic approximation and a first attempt at a numerical analysis is made. https://portal.research.lu.se/en/publications/0076c3db-d9f5-43aa-b6b2-acf7a040aa1f American Physical Society 2010 eng Subatomic Physics 1550-2368 1675228 000280759400003 77956802978 10.1103/PhysRevD.82.034506 http://dx.doi.org/10.1103/PhysRevD.82.034506 yes 82 3 034506 https://www.scopus.com/pages/publications/77956802978 0076c3db-d9f5-43aa-b6b2-acf7a040aa1f 2016-04-01T09:47:29+02:00 2025-10-14T12:25:26+02:00 2016-04-01T09:47:29+02:00 15 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Nora Ausmees author 8f3c0c87-1b1b-4dd8-9444-755a0151ab3a Molecular Cell Biology v1000612 department Streptomyces is a multicellular mycelial bacterium, which exhibits pronounced cell polarity and grows by extension of the hyphal tips. Similarly to other polarly growing walled cells, such as filamentous fungi or pollen tubes, Streptomyces hyphae face an intrinsic problem: addition of new cell wall material causes structural weakness of the elongating tip. Cellular strategies employed by walled cells to cope with this problem are not well understood. We have identified a coiled coil protein FilP, with properties similar to those of animal intermediate filament (IF) proteins, which somehow confers rigidity and elasticity to the Streptomyces hyphae. In a recent publication we showed that FilP forms extensive cis-interconnected networks, which likely explain its biological function in determining the mechanical properties of the cells. Surprisingly, the intrinsically non-dynamic cytoskeletal network of FilP exhibits a dynamic behavior in vivo and assembles into growth-dependent polar gradients. We show that apical accumulation of FilP is dependent on its interaction with the main component of the Streptomyces polarisome, DivIVA. Thus, the same polarisome complex that orchestrates cell elongation, also recruits an additional stress-bearing structure to the growing tips with an intrinsically weak cell wall. Similar strategy might be used by all polarly growing walled cells. https://portal.research.lu.se/en/publications/de4678d5-ee3d-4305-a35e-24fe104ad95a Landes Bioscience 2013 eng FilP Streptomyces coiled coil cytoskeleton intermediate filament polar growth Biological Sciences 1949-0992 4066311 24002529 84922395106 10.4161/bioa.26194 http://dx.doi.org/10.4161/bioa.26194 yes 3 4 110 112 https://www.scopus.com/pages/publications/84922395106 de4678d5-ee3d-4305-a35e-24fe104ad95a 2016-04-01T09:47:29+02:00 2025-10-14T09:35:45+02:00 2016-04-01T09:47:29+02:00 16 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Alexandros Sopasakis author 15019cdb-2aca-4dd2-a31d-e9c428d42804 Mathematics (Faculty of Engineering) v1000667 department eSSENCE: The e-Science Collaboration v1001240 department We introduce a lattice-free hard sphere exclusion stochastic process. The resulting stochastic rates are distance based instead of cell based. The corresponding Markov chain build for this many particle system is updated using an adaptation of the kinetic Monte Carlo method. It becomes quickly apparent that due to the lattice-free environment, and because of that alone, the dynamics behave differently than those in the lattice-based environment. This difference becomes increasingly larger with respect to particle densities/temperatures. The well-known packing problem and its solution (Palasti conjecture) seem to validate the resulting lattice-free dynamics. https://portal.research.lu.se/en/publications/729c07bb-3acd-4016-bd40-6e2dfebf37cb Global Science Press 2012 eng Lattice-free microscopic stochastic dynamics kinetic Monte Carlo Mathematical Sciences 1991-7120 2826387 000303773200004 84858264637 10.4208/cicp.110211.200611a http://dx.doi.org/10.4208/cicp.110211.200611a yes 12 3 691 702 https://www.scopus.com/pages/publications/84858264637 729c07bb-3acd-4016-bd40-6e2dfebf37cb 2016-04-01T09:47:30+02:00 2025-10-14T12:40:23+02:00 2016-04-01T09:47:30+02:00 17 info:srw/schema/1/mods-v3.3xml journalArticle published yes 4 Thord von Schewelov author c61e5a95-90d4-4b21-9c4f-9c55af69e3eb Åke Carlsson author 27ca355c-9543-4145-a10d-2617037defcf Lennart Sanzén author 68706d7a-02d2-4c69-a5bc-4cd6c6a611fe Jack Besjakov author e8c28ea6-6152-4405-8a47-23ed46a9b78f Orthopedics v1000532 department Radiology Diagnostics, Malmö v1000580 department Orthopedics research group Radiology Diagnostics, Malmö research group In 2005, we demonstrated that the polished triple-tapered C-stem at two years had migrated distally and rotated internally. From that series, 33 patients have now been followed radiologically, clinically and by radiostereometric analysis (RSA) for up to ten years. The distal migration within the cement mantle had continued and reached a mean of 2 mm (0.5 to 4.0) at ten years. Internal rotation, also within the cement mantle, was a mean 3.8° (external 1.6° to internal 6.6°) The cement mantle did not show any sign of migration or loosening in relation to the femoral bone. There were no clinical or radiological signs indicating that the migration or rotation within the cement mantle had had any adverse effects for the patients. Cite this article: Bone Joint J 2014;96-B:604-8. https://portal.research.lu.se/en/publications/997141f7-11c8-426e-b46e-49f25bda7247 British Editorial Society of Bone & Joint Surgery 2014 eng Orthopaedics http://www.ncbi.nlm.nih.gov/pubmed/24788493?dopt=Abstract yes 2049-4408 4455974 24788493 000335911100008 84900545221 24788493 10.1302/0301-620X.96B5.33580 http://dx.doi.org/10.1302/0301-620X.96B5.33580 yes 96B 5 604 608 https://www.scopus.com/pages/publications/84900545221 997141f7-11c8-426e-b46e-49f25bda7247 2016-04-01T09:47:30+02:00 2025-10-14T10:16:23+02:00 2016-04-01T09:47:30+02:00 18 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Carl Turesson author 9796c11a-ed4c-4183-bbbc-bdf96d2fbfd5 Internal Medicine - Epidemiology v1000520 department EpiHealth: Epidemiology for Health v1001239 department Internal Medicine - Epidemiology research group PURPOSE OF REVIEW: To discuss recent findings on the epidemiology and pathogenesis of extra-articular manifestations in rheumatoid arthritis (RA), and provide an update on the literature on treatment of patients with extra-articular RA (ExRA) manifestations. RECENT FINDINGS: ExRA is associated with increased comorbidity and mortality. Several surveys suggest that some ExRA manifestations, in particular vasculitis, occur less frequently than previously reported. This is probably due to improved overall control of disease activity. Active RA with high disease activity is associated with increased risk of severe ExRA manifestations. Studies on the impact of treatment with biologics on the occurrence of ExRA are inconclusive. Circulating immune complexes and T cells have been implicated in the pathogenesis of ExRA. The genetic background and related disease mechanisms may be somewhat different in manifestations such as vasculitis and interstitial lung disease. Limited data support a benefit from treatment with cyclophosphamide, TNF-inhibitors or rituximab in patients with severe ExRA. SUMMARY: ExRA remains a major diagnostic and therapeutic challenge in some patients. Further studies of the pathogenesis of systemic involvement and on the effect of treatment on such mechanisms may be helpful for further improvement of the management of RA. https://portal.research.lu.se/en/publications/205cc950-18f6-4d60-9cac-07b0793992ce Lippincott Williams & Wilkins 2013 eng Clinical Medicine http://www.ncbi.nlm.nih.gov/pubmed/23425964?dopt=Abstract yes 1531-6963 3559569 000316942900011 23425964 84875907505 23425964 10.1097/BOR.0b013e32835f693f http://dx.doi.org/10.1097/BOR.0b013e32835f693f yes 25 3 360 366 https://www.scopus.com/pages/publications/84875907505 205cc950-18f6-4d60-9cac-07b0793992ce 2016-04-01T09:47:30+02:00 2025-10-14T11:15:36+02:00 2016-04-01T09:47:30+02:00 19 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Dirk-Jan ten Brink author e7559940-6abd-4d06-a00a-5c510fee3ef8 Harmen Pieter Hendriksma author Hans Henrik Bruun author 6a87659b-2cf1-45bd-b4e8-b7b923143b75 Functional zoology v1000610 department Background and AimsThis study examined the adaptive association between seed germination ecology and specialization to either forest or open habitats across a range of evolutionary lineages of seed plants, in order to test the hypotheses that (1) species' specialization to open vs. shaded habitats is consistently accompanied by specialization in their regeneration niche; and (2) species are thereby adapted to utilize different windows of opportunity in time (season) and space (habitat).MethodsSeed germination response to temperature, light and stratification was tested for 17 congeneric pairs, each consisting of one forest species and one open-habitat species. A factorial design was used with temperature levels and diurnal temperature variation (10 °C constant, 15-5 °C fluctuating, 20 °C constant, 25-15 °C fluctuating), and two light levels (light and darkness) and a cold stratification treatment. The congeneric species pair design took phylogenetic dependence into account.Key ResultsSpecies from open habitats germinated better at high temperatures, whereas forest species performed equally well at low and high temperatures. Forest species tended to germinate only after a period of cold stratification that could break dormancy, while species from open habitats generally germinated without cold stratification. The empirically derived germination strategies correspond quite well with establishment opportunities for forest and open-habitat plant species in nature.ConclusionsAnnual changes in temperature and light regime in temperate forest delimit windows of opportunity for germination and establishment. Germination strategies of forest plants are adaptations to utilize such narrow windows in time. Conversely, lack of fit between germination ecology and environment may explain why species of open habitats generally fail to establish in forests. Germination strategy should be considered an important mechanism for habitat specialization in temperate herbs to forest habitats. The findings strongly suggest that phases in the plant life cycle other than the established phase should be considered important in adaptive specialization. https://portal.research.lu.se/en/publications/a062459a-87ae-4150-8530-a5d23899b11c Oxford University Press 2012-11-27 eng germination cueing Habitat specialization beta niche dormancy forest herbs phylogenetically independent contrasts (PICs) plant functional traits regeneration niche shade monocotyledons dicotyledons. Zoology 0305-7364 3218441 000314057400011 23186835 84877590017 23186835 10.1093/aob/mcs253 http://dx.doi.org/10.1093/aob/mcs253 yes https://www.scopus.com/pages/publications/84877590017 a062459a-87ae-4150-8530-a5d23899b11c 2016-04-01T09:47:31+02:00 2025-10-14T13:02:00+02:00 2016-04-01T09:47:31+02:00 20 1.1datelastChanged &gt;= 2019-01datelastChanged>=2019-01