1.1 565 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 Ivar Dimberg author Bartosz Grzymala-Lubanski author Anette Hagerfelth author Marten Rosenqvist author Peter Svensson author 9beb5ebe-3809-43d2-9688-81a0ea56cfe9 Anders Sjalander author Clinical Coagulation, Malmö v1000575 department Clinical Coagulation, Malmö research group Background: Well-managed warfarin treatment with a high time in therapeutic range (TTR) corresponds to fewer bleedings or thromboembolic complications. Many small centres manage their warfarin dosing manually, with little or no knowledge of their treatment quality as measured by TTR. AuriculA is a Swedish National web-based anticoagulation dosing system. Our hypothesis was that the web based dosing system, compared to manual dosing, would improve the TTR. Methods: Retrospective cohort study of medical records from patients with atrial fibrillation on warfarin treatment from two centres, with previously manual warfarin dosing regimens. Data for calculation of TTR was extracted manually from medical records from the time when using manual dosing and compared with the computerised regimen. Results: In centre 1, the mean TTR was significantly increased after the introduction of AuriculA, from 64.3% (95% CI 58.8-69.8) to 71.3% (95% CI 67.7-74.8), p=0.03. In centre 2, a high TTR of 73.6% (95% CI 71.3-75.9) was maintained after the implementation, 74.0% (95% CI 71.6-76.3). INR tests were prescribed significantly more frequent after the introduction of AuriculA in both centres; 20% more often at centre 1 and 21% at centre 2. Conclusion: Computerised dosing assistance within the Swedish national quality registry AuriculA improves or maintains a high treatment quality with warfarin as measured by TTR. (C) 2012 European Federation of Internal Medicine. Published by Elsevier B. V. All rights reserved. https://portal.research.lu.se/en/publications/1f28a09f-e238-41a8-90a1-8c4eb1703550 Elsevier 2012 eng Anticoagulation Warfarin Atrial fibrillation General Medicine 1879-0828 3256241 000310577800023 84869085735 22917757 10.1016/j.ejim.2012.07.011 http://dx.doi.org/10.1016/j.ejim.2012.07.011 yes 23 8 742 744 https://www.scopus.com/pages/publications/84869085735 1f28a09f-e238-41a8-90a1-8c4eb1703550 2016-04-01T09:53:20+02:00 2025-10-14T10:55:05+02:00 2016-04-01T09:53:20+02:00 1 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Elin Trägårdh author 96079361-69fb-4f14-a32e-0bc9d6c18a6c Marcus Carlsson author d63f9457-377d-47fe-bd89-aa272b6d0480 Lars Edenbrandt author 9f2ff310-224b-4f3b-b3ab-9471b06a3968 Clinical Physiology (Lund) v1000467 department Nuclear medicine, Malmö v1000565 department Lund Cardiac MR Group v1001127 department Nuclear medicine, Malmö research group Lund Cardiac MR Group research group https://portal.research.lu.se/en/publications/b663a36f-37c9-4e29-b41a-5dd1a1b8a8e8 Springer 2015 eng Cardiology and Cardiovascular Disease http://www.ncbi.nlm.nih.gov/pubmed/25500801?dopt=Abstract yes 1532-6551 4908446 25500801 000361622400006 84942294926 25500801 10.1007/s12350-014-0041-z http://dx.doi.org/10.1007/s12350-014-0041-z yes 22 5 885 887 https://www.scopus.com/pages/publications/84942294926 b663a36f-37c9-4e29-b41a-5dd1a1b8a8e8 2016-04-01T10:13:20+02:00 2025-10-14T10:59:54+02:00 2016-04-01T10:13:20+02:00 2 info:srw/schema/1/mods-v3.3xml journalArticle published yes 8 Cecilia Nakeva von Mentzer author Björn Lyxell author Birgitta Sahlén author 7a74e019-6dd2-4243-9dad-3ca9653bc47e Örjan Dahlström author Magnus Lindgren author f4d9fcd8-69a1-4b2d-9ea9-40d0d3e06898 Marianne Ors author 0190fc52-1d56-4531-9f3b-7cf5c5611bb2 Petter Kallioinen author Inger Uhlén author Logopedics, Phoniatrics and Audiology v1000449 department Department of Psychology v1000681 department Clinical Neurophysiology v1000448 department Thinking in Time: Cognition, Communication and Learning project https://portal.research.lu.se/en/publications/83a0d7ba-8392-4846-bd4a-3c77756989cc Wiley-Blackwell 2014 eng Psychology 1467-9450 4500036 000341908300007 84926488186 25078707 10.1111/sjop.12149 http://dx.doi.org/10.1111/sjop.12149 yes 55 5 448 455 https://www.scopus.com/pages/publications/84926488186 83a0d7ba-8392-4846-bd4a-3c77756989cc 2016-04-01T10:32:26+02:00 2025-10-14T10:47:58+02:00 2016-04-01T10:32:26+02:00 3 info:srw/schema/1/mods-v3.3xml journalArticle published yes 8 Cecilia Nakeva von Mentzer author Börn Lyxell author Birgitta Sahlén author 7a74e019-6dd2-4243-9dad-3ca9653bc47e Malin Wass author Magnus Lindgren author f4d9fcd8-69a1-4b2d-9ea9-40d0d3e06898 Marianne Ors author 0190fc52-1d56-4531-9f3b-7cf5c5611bb2 Petter Kallioinen author 2d00075a-9845-48c5-9f40-72809dab149e Inger Uhlén author Logopedics, Phoniatrics and Audiology v1000449 department Department of Psychology v1000681 department Clinical Neurophysiology v1000448 department Thinking in Time: Cognition, Communication and Learning project https://portal.research.lu.se/en/publications/af8de4d6-7ec5-4e38-aa0a-bce9195fc69e Elsevier 2013 eng Psychology 1872-8464 4091238 000328870800027 84889574680 24210843 10.1016/j.ijporl.2013.10.007 http://dx.doi.org/10.1016/j.ijporl.2013.10.007 yes 77 12 2049 2057 https://www.scopus.com/pages/publications/84889574680 af8de4d6-7ec5-4e38-aa0a-bce9195fc69e 2016-04-01T10:51:54+02:00 2025-10-14T13:26:36+02:00 2016-04-01T10:51:54+02:00 4 info:srw/schema/1/mods-v3.3xml journalArticle published yes 5 Bartosz Grzymala-Lubanski author Sara Sjalander author Henrik Renlund author Peter Svensson author 9beb5ebe-3809-43d2-9688-81a0ea56cfe9 Anders Sjalander author Clinical Coagulation, Malmö v1000575 department Clinical Coagulation, Malmö research group Introduction: Warfarin treatment with a high time in therapeutic range (TTR) is correlated to fewer complications. The TTR in Sweden is generally high but varies partly depending on local expertise and traditions. A dosing algorithm could minimize variations and increase treatment quality. Here we evaluate the performance of a computerized dosing algorithm. Materials and methods: 53.779 warfarin treated patients from 125 centers using the Swedish national quality registry AuriculA. If certain criteria are met, the algorithm gives one of seven possible dose suggestions, which can be unchanged, decreased or increased weekly dose by 5, 10 or 15%. The outcome evaluated by the resulting INR value was compared between dose suggestions arising from the algorithm that were accepted and those that were manually changed. There were no randomization, and outcomes were retrospectively analyzed. Results: Both the algorithm-based and the manually changed doses had worse outcome if only two instead of three previous INR values were available. The algorithm suggestions were superior to manual dosing regarding percent samples within the target range 2-3 (hit-rate) or deviation from INR 2.5 (mean error). Of the seven possible outcomes from the algorithm, six were significantly superior and one equal to the manually changed doses when three previous INR:s were present. Conclusions: The algorithm-based dosing suggestions show better outcome in most cases. This can make dosing of warfarin easier and more efficient. There are however cases where manual dosing fares better. Here the algorithm will be improved to further enhance its dosing performance in the future. (c) 2012 Elsevier Ltd. All rights reserved. https://portal.research.lu.se/en/publications/f4740c17-514e-4762-aa0e-4b2bf646bff6 Elsevier 2013 eng Anticoagulation Atrial fibrillation Computer-assisted therapy INR Warfarin Cardiology and Cardiovascular Disease http://www.ncbi.nlm.nih.gov/pubmed/23232091 1879-2472 3591210 000313719400009 84872293345 23232091 10.1016/j.thromres.2012.11.016 http://dx.doi.org/10.1016/j.thromres.2012.11.016 yes 131 2 130 134 https://www.scopus.com/pages/publications/84872293345 f4740c17-514e-4762-aa0e-4b2bf646bff6 2016-04-01T10:52:58+02:00 2025-10-14T10:20:28+02:00 2016-04-01T10:52:58+02:00 5 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Birte Tornöe author 7618c5a2-80ea-48d1-8688-073d183fd35b Liselotte Skov author Department of Health Sciences v1000411 department This pilot study evaluated the effect of computer animated relaxation therapy in children between 7 and 13 years with tension-type headache and the children's experiences with the therapy. The therapy consisted of an uncontrolled nine-session course in modified progressive relaxation therapy assisted by computer animated surface EMG provided from the trapezius muscles and with the physiotherapist as a participant observer. Outcome measures were (a) headache frequency and intensity, (b) pericranial tenderness, (c) tension patterns, and (d) evaluations assessed at baseline and at 3 months follow up. Nine children, mean age 10.9 (SD 1.7) years, diagnosed with frequent episodic or chronic tension-type headache completed the course. The results showed a mean improvement of 45% for headache frequency at 3 months follow up versus baseline and a significant reduction in headache frequency for all participants and in Total Tenderness Score for children with frequent episodic tension-type headache. The children expressed a growing understanding of body reactions and an acquired ability to deactivate and regulate these reactions. Computer animated SEMG seems an applicable learning strategy for young headache sufferers. This study suggests that children below the age of 13 need both the dialog and guidance from a participant observer in order to achieve body awareness. https://portal.research.lu.se/en/publications/36a74bfe-9c14-4289-9db2-644a78f413a3 Springer 2012 eng Tension-type headache in children Computer animated SEMG Progressive relaxation Body awareness Learning strategies Psychology 1573-3270 2826836 000303876500005 84863007677 22080435 10.1007/s10484-011-9173-y http://dx.doi.org/10.1007/s10484-011-9173-y yes 37 1 35 44 https://www.scopus.com/pages/publications/84863007677 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Nursing (Closed 2012) (013065000) 36a74bfe-9c14-4289-9db2-644a78f413a3 2016-04-01T11:15:04+02:00 2025-10-14T09:35:20+02:00 2016-04-01T11:15:04+02:00 6 info:srw/schema/1/mods-v3.3xml conference paper published yes 1 Bertil Ekdahl author a3a723f6-ab49-47d8-995b-ae86e69b647f Department of Computer Science v1000234 department Robotics and Semantic Systems v1001420 department 8th International Conference on Computing Anticipatory Systems (CASYS 07) In 1958, two years after the Dartmouth conference, where the term artificial intelligence was coined, Herbert Simon and Allen Newell asserted the existence of "machines that think, that learn and create". They were further prophesying that the machines' capacity would increase and be oil par with the human mind. Now, 50 years later, computers perform many more tasks than one could imagine in the 1950s but, virtually, no computer can do more than could the first digital computer, developed by John von Neumann in the 1940s. Computers still follow algorithms, they do not create them. However, the development of nanotechnology seems to have given rise to new hopes. With nanotechnology two things are Supposed to happen. Firstly, due to the small scale it will be possible to construct huge Computer memories which are supposed to be the precondition for building an artificial brain, secondly, nanotechnology will make it possible to scan the brain which in turn will make reverse engineering possible: the mind will be decoded by studying the brain. The consequence of such a belief is that the brain is no more than a calculator, i.e., all that the mind can do is in principle the results of arithmetical operations. Computers are equivalent to formal systems which in turn was an answer to an idea by Hilbert that proofs should contain ideal statements for which operations cannot be applied in a contentual way. The advocates of artificial intelligence will place content in a machine that is developed not only to be free of content but also cannot contain content. In this paper I argue that the hope for artificial intelligence is in vain https://portal.research.lu.se/en/publications/9aa97cc0-1c94-4654-a999-77ab1bf6f650 American Institute of Physics (AIP) 2008 2007-08-06 - 2007-08-11 eng Artificial intelligence linguistic complementarity mechanical system Turing machine semantics formal system Computer Sciences 1551-7616 0094-243X 1376266 000262094700025 57049091525 1051 283 292 https://www.scopus.com/pages/publications/57049091525 9aa97cc0-1c94-4654-a999-77ab1bf6f650 2016-04-01T11:48:32+02:00 2026-01-02T01:12:59+01:00 2016-04-01T11:48:32+02:00 7 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Björn Breidegard author 01c6bb47-7d8d-446d-99c5-5b1e70e69de4 Certec - Rehabilitation Engineering and Design v1000236 department Certec - Rehabilitation Engineering and Design research group This article presents the first technology ever for on-line registration and interactive and automatic analysis of<br/><br> finger movements during tactile reading (Braille and tactile pictures). Interactive software has been developed for registration (with two cameras and a microphone), MPEG-2 video compression and storage on disk or DVD as well<br/><br> as an Interactive Analysis Program to aid human analysis. An Automatic Finger Tracking System has been implemented which also semi-automatically tracks the reading aloud speech on the syllable level. This set of tools opens the way for large scale studies of blind people reading Braille or tactile images. It has been tested in a pilot project involving congenitally blind subjects reading texts and pictures. https://portal.research.lu.se/en/publications/f21fd0d7-f6c5-4392-944b-288fab360a9d Springer 2007 eng Metod- och teoribildning Synskador och blindhet certec Human Computer Interaction http://www.ingentaconnect.com/content/psocpubs/berm/2007/00000039/00000004/art00016 yes http://www.certec.lth.se/dok/attgora/ yes 1554-3528 754976 000251492800016 37349007339 39 4 824 834 https://www.scopus.com/pages/publications/37349007339 f21fd0d7-f6c5-4392-944b-288fab360a9d 2016-04-01T11:54:05+02:00 2025-10-14T10:21:20+02:00 2016-04-01T11:54:05+02:00 8 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Leif Uttman author 2fac7236-f06f-4e87-885c-afbf4886cdae Björn Jonson author d1baeda4-a036-4c0a-b842-e2552fab0cae Clinical Physiology (Lund) v1000467 department BACKGROUND: Ventilator resetting is frequently needed to adjust tidal volume, pressure and gas exchange. The system comprising lungs and ventilator is so complex that a trial and error strategy is often applied. Comprehensive characterization of lung physiology is feasible by monitoring. The hypothesis that the effect of ventilator resetting could be predicted by computer simulation based on a physiological profile was tested in healthy pigs. METHODS: Flow, pressure and CO2 signals were recorded in 7 ventilated pigs. Elastic recoil pressure was measured at postinspiratory and post-expiratory pauses. Inspiratory and expiratory resistance as a function of volume and compliance were calculated. CO2 elimination per breath was expressed as a function of tidal volume. Calculating pressure and flow moment by moment simulated the effect of ventilator action, when respiratory rate was varied between 10 and 30 min(-1) and minute volume was changed so as to maintain PaCO2. Predicted values of peak airway pressure, plateau pressure, and CO2 elimination were compared to values measured after resetting. RESULTS: With 95% confidence, predicted pressures and CO2 elimination deviated from measured values with &lt; 1 cm H2O and &lt; 6%, respectively. CONCLUSION: It is feasible to predict effects of ventilator resetting on the basis of a physiological profile at least in health. https://portal.research.lu.se/en/publications/f5b83306-5992-43ff-8a23-acd5b8b9a9e4 https://portal.research.lu.se/files/2741407/623594.pdf application/pdf 214702 no Blackwell Munksgaard 2002 eng Signal Processing Respiratory Mechanics Artificial Respiration Lung Compliance Human Computer Simulation Carbon Dioxide : analysis Breath Tests Animal Airway Resistance Anesthesia Computer-Assisted Support Non-U.S. Gov't Swine Therapy Anesthesiology and Intensive Care 0001-5172 107474 11939920 000174808200011 0036210033 10.1034/j.1399-6576.2002.460311.x http://dx.doi.org/10.1034/j.1399-6576.2002.460311.x yes 46 3 289 296 https://www.scopus.com/pages/publications/0036210033 f5b83306-5992-43ff-8a23-acd5b8b9a9e4 2016-04-01T12:00:33+02:00 2025-10-14T13:13:10+02:00 2016-04-01T12:00:33+02:00 9 info:srw/schema/1/mods-v3.3xml journalArticle published yes 1 Bernt Nilsson author fc637d52-2533-4d07-adf5-2fd5c10752bb Division of Chemical Engineering v1000243 department https://portal.research.lu.se/en/publications/7db7a84b-b0df-4dfb-908e-64959181e40b Elsevier 2005 eng Chemical Engineering 1873-4863 3917767 000231195200105 118 30 31 7db7a84b-b0df-4dfb-908e-64959181e40b 2016-04-01T12:05:02+02:00 2025-04-04T15:13:41+02:00 2016-04-01T12:05:02+02:00 10 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 M Dubiel author GH Breborowicz author M Ropacka author M Pietryga author D Maulik author Saemundur Gudmundsson author 151f6c5f-1f40-4c9b-8328-d001b9ce2ffb Department of Clinical Sciences, Malmö v1000476 department Three-dimensional (3-D) ultrasound (US) has greatly improved evaluation of organ circulation. The aim of this study was to explore the possible use of this new technique in normal and high-risk pregnancies. Fetal brain, lung and placenta 3-D power Doppler signal intensity were recorded in 115 normal singleton pregnancies (24 to 42 weeks gestation) and in 67 high-risk pregnancies. Mean image pixel signal intensity was calculated for each organ and a brain-lung ratio. In normal pregnancy, placental and lung signal intensity increased until 33, with a rapid decrease after 38, weeks of gestation. Fetal cerebral signal intensity increased with gestational age. Placental and fetal lung signal intensity was significantly lower in high-risk pregnancies than in the control group, with increased fetal brain and brain-lung ratios. The present results suggest a reduction of placental perfusion after 38 weeks of gestation in normal pregnancy, with redistribution of fetal circulation. Lung signal intensity increased abruptly at 32 weeks of gestation, which might reflect lung maturity. The new method showed signs of centralization of fetal circulation at the end of gestation. The results might suggest a possible clinical use for fetal surveillance in high-risk pregnancies. https://portal.research.lu.se/en/publications/bad0c555-aff2-4c3c-86c9-504231f3c8e9 Elsevier 2005 eng three-dimensional power angiography fetus blood flow computer pregnancy analysis Doppler Radiology and Medical Imaging 0301-5629 897088 000227591200006 15749554 14744270027 15749554 10.1016/j.ultrasmedbio.2004.12.008 http://dx.doi.org/10.1016/j.ultrasmedbio.2004.12.008 yes 31 3 321 327 https://www.scopus.com/pages/publications/14744270027 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400) bad0c555-aff2-4c3c-86c9-504231f3c8e9 2016-04-01T12:07:57+02:00 2025-10-14T13:20:59+02:00 2016-04-01T12:07:57+02:00 11 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Per Nilsson author 9d75549c-2fe9-4d87-84f4-cda58255b8ac B Persson author Medical Radiation Physics, Lund v1000468 department A hyperthermia system which has been developed for clinical use is described. Different direct-contact applicators working at the ISM microwave frequency of 915 MHz are used for inducing heat in superficial tumours to a depth of about 3 cm. The system is a further development of an earlier prototype which worked at 2450 MHz. The microwave generator is controlled by a microcomputer governed by temperature measurements with thermistor probes inserted into the tissue. To minimise the influence of the interaction between the microwaves and the temperature probes, a pulsed irradiation technique is used. Up to July 1984, 80 superficial tumours had been treated with radiotherapy combined with local hyperthermia applied using this system. https://portal.research.lu.se/en/publications/6b290525-bbb0-418c-99e6-cd2ec589bdb3 IOP Publishing 1985 eng Radiology and Medical Imaging 1361-6560 1103386 4001156 36149038767 10.1088/0031-9155/30/4/001 http://dx.doi.org/10.1088/0031-9155/30/4/001 yes 30 4 283 292 https://www.scopus.com/pages/publications/36149038767 6b290525-bbb0-418c-99e6-cd2ec589bdb3 2016-04-01T12:09:36+02:00 2025-10-14T11:19:20+02:00 2016-04-01T12:09:36+02:00 12 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Anders Thapper author Robert J Deeth author Ebbe Nordlander author d1ae8493-64b8-4f36-810a-6b8aa8d1a720 Department of Chemistry v1000647 department https://portal.research.lu.se/en/publications/e32024d8-4906-4b84-9a01-4c5a94150441 The American Chemical Society (ACS) 1999 eng Inorganic Chemistry 1520-510X 959738 0001110764 10.1021/ic980646g http://dx.doi.org/10.1021/ic980646g yes 38 5 1015 1018 https://www.scopus.com/pages/publications/0001110764 e32024d8-4906-4b84-9a01-4c5a94150441 2016-04-01T12:14:42+02:00 2025-10-14T10:50:37+02:00 2016-04-01T12:14:42+02:00 13 info:srw/schema/1/mods-v3.3xml journalArticle published yes 7 Lene Rosendahl author Peter Blomstrand author Einar Heiberg author 0a1601d9-046e-49fa-a1ae-bd5f2ad2011c Jan Ohlsson author Per-Gunnar Bjoerklund author Britt-Marie Ahlander author Jan Engvall author Clinical Physiology (Lund) v1000467 department Lund Cardiac MR Group v1001127 department Lund Cardiac MR Group research group Background: Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and to measure the time saved. Methods: Delayed enhancement magnetic resonance imaging was performed in 40 patients where myocardial perfusion single photon emission computed tomography imaging showed irreversible uptake reduction suggesting a myocardial scar. After segmentation, the semi-automatic software was applied. A scar area was displayed, which could be corrected and compared with manual delineation. The different time steps were recorded with both methods. Results: The software shortened the average evaluation time by 12 4 min per cardiac exam, compared with manual delineation. There was good correlation of myocardial volume, infarct volume and infarct percentage (%) between the two methods, r = 0 95, r = 0 92 and r = 0 91 respectively. Conclusion: A computer software for myocardial volume and infarct size determination cut the evaluation time by more than 50% compared with manual assessment, with maintained clinical accuracy. https://portal.research.lu.se/en/publications/7989ade3-02fa-4078-bba2-e1e66844aa3e Wiley-Blackwell 2008 eng time saving semi-automatic magnetic resonance imaging computer software myocardial infarct size Physiology and Anatomy 1475-0961 966152 000251629100001 37349011248 10.1111/j.1475-097X.2007.00765.x http://dx.doi.org/10.1111/j.1475-097X.2007.00765.x yes 28 1 1 7 https://www.scopus.com/pages/publications/37349011248 7989ade3-02fa-4078-bba2-e1e66844aa3e 2016-04-01T12:16:15+02:00 2025-10-14T12:45:36+02:00 2016-04-01T12:16:15+02:00 14 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Birgitta Roos author 4897e3c5-68cd-4e2a-b080-0415f57a8c1d Harry J Whitlow author d57b9259-cfca-4c0f-946d-bd13befd6da5 Medical Radiation Physics, Lund v1000468 department Nuclear physics v1000629 department https://portal.research.lu.se/en/publications/87bbd011-8305-455c-afc1-d53a23728de6 Lippincott Williams & Wilkins 2003 eng Radiology and Medical Imaging http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12498519&dopt=Abstract yes 1538-5159 111754 12498519 000179932900006 0037213307 84 1 72 81 https://www.scopus.com/pages/publications/0037213307 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Nuclear Physics (Faculty of Technology) (011013007) 87bbd011-8305-455c-afc1-d53a23728de6 2016-04-01T12:18:32+02:00 2025-10-14T11:24:33+02:00 2016-04-01T12:18:32+02:00 15 info:srw/schema/1/mods-v3.3xml journalArticle published yes 6 Milad El-Segaier author 2a33f487-edfc-4ee5-9db5-fca00d9e76d5 O Lilja author S Lukkarinen author Leif Sörnmo author 6f12338a-b2af-4787-99ab-c30b14b572b5 R Sepponen author Erkki Pesonen author ece8dd1a-f7ea-4a6f-aec9-e2d8db9d28d5 Paediatrics (Lund) v1000473 department Department of Electrical and Information Technology v1000242 department Integrated Electronic Systems v1001101 department https://portal.research.lu.se/en/publications/1bbfdee2-1e30-4413-ae22-823f3e5b9bb0 Springer 2005 eng Clinical Medicine http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16060534&dopt=Abstract yes 1573-9686 143020 000230431700009 16060534 22344442029 10.1007/s10439-005-4053-3 http://dx.doi.org/10.1007/s10439-005-4053-3 yes 33 7 937 942 https://www.scopus.com/pages/publications/22344442029 1bbfdee2-1e30-4413-ae22-823f3e5b9bb0 2016-04-01T12:20:56+02:00 2025-10-23T15:49:06+02:00 2016-04-01T12:20:56+02:00 16 info:srw/schema/1/mods-v3.3xml journalArticle published yes 5 Leif Uttman author 2fac7236-f06f-4e87-885c-afbf4886cdae Helena Ögren author Lisbet Niklason author a3a54caa-cfc6-42f3-b2da-7d042413bcac Björn Drefeldt author 3cdc0a49-9768-4001-a506-a58ece8f63ed Björn Jonson author d1baeda4-a036-4c0a-b842-e2552fab0cae Clinical Physiology (Lund) v1000467 department Introduction To prevent further lung damage in patients with acute respiratory distress syndrome ( ARDS), it is important to avoid overdistension and cyclic opening and closing of atelectatic alveoli. Previous studies have demonstrated protective effects of using low tidal volume ( VT), moderate positive end-expiratory pressure and low airway pressure. Aspiration of dead space ( ASPIDS) allows a reduction in VT by eliminating dead space in the tracheal tube and tubing. We hypothesized that, by applying goal-orientated ventilation based on iterative computer simulation, VT can be reduced at high respiratory rate and much further reduced during ASPIDS without compromising gas exchange or causing high airway pressure. Methods ARDS was induced in eight pigs by surfactant perturbation and ventilator-induced lung injury. Ventilator resetting guided by computer simulation was then performed, aiming at minimal VT, plateau pressure 30 cmH(2)O and isocapnia, first by only increasing respiratory rate and then by using ASPIDS as well. Results VT decreased from 7.2 +/- 0.5 ml/kg to 6.6 +/- 0.5 ml/kg as respiratory rate increased from 40 to 64 +/- 6 breaths/min, and to 4.0 +/- 0.4 ml/kg when ASPIDS was used at 80 +/- 6 breaths/min. Measured values of arterial carbon dioxide tension were close to predicted values. Without ASPIDS, total positive end-expiratory pressure and plateau pressure were slightly higher than predicted, and with ASPIDS they were lower than predicted. Conclusion In principle, computer simulation may be used in goal-oriented ventilation in ARDS. Further studies are needed to investigate potential benefits and limitations over extended study periods. https://portal.research.lu.se/en/publications/9f6a1e36-1f5f-4e3e-bc22-883db477d811 BioMed Central (BMC) 2007 eng Anesthesiology and Intensive Care 1364-8535 659659 000247721200006 34147118131 10.1186/cc5719 http://dx.doi.org/10.1186/cc5719 11 2 https://www.scopus.com/pages/publications/34147118131 9f6a1e36-1f5f-4e3e-bc22-883db477d811 2016-04-01T12:22:00+02:00 2025-10-14T10:44:15+02:00 2016-04-01T12:22:00+02:00 17 info:srw/schema/1/mods-v3.3xml journalArticle published yes 2 Magnus Jonsson author 4b424301-0ef8-44c6-90e6-abb9fd5873e4 Joyce Carlson author 61097605-3056-4d0b-af3a-e97a51854836 Clinical Chemistry, Malmö v1000574 department Clinical Chemistry, Malmö research group https://portal.research.lu.se/en/publications/9af78bde-7a08-4464-a32d-69b11c5e98f0 Oxford University Press 2002 eng Iron-Deficiency: diagnosis Autoanalysis Computer-Assisted Capillary Support ROC Curve Human Inflammation: diagnosis Numerical Analysis Non-U.S. Gov't Blood Proteins: analysis Computers Electrophoresis Adult Algorithms Anemia Biological Sciences http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12089178&dopt=Abstract http://www.clinchem.org/cgi/content/abstract/48/7/1084 0009-9147 115175 12089178 000176373200018 0036095991 48 7 1084 1093 https://www.scopus.com/pages/publications/0036095991 9af78bde-7a08-4464-a32d-69b11c5e98f0 2016-04-01T12:23:07+02:00 2025-10-14T11:39:26+02:00 2016-04-01T12:23:07+02:00 18 info:srw/schema/1/mods-v3.3xml journalArticle published yes 4 A. G. Bobba author B. Ventresca author V. P. Singh author Lars Bengtsson author 7e9bd679-0f0e-4a8d-ac6e-01b5e74b9000 Division of Water Resources Engineering v1000225 department High hydrogen ion concentrations of runoff events were analyzed in terms of the probability distributions of frequency, duration, magnitude, and time of occurrence. Simple stochastic models were applied to the probability distributions of the annual frequency of high hydrogen ion concentration flows and their magnitudes. A consideration of the statistical properties of the given stochastic variables led to the development of a technique with which higher hydrogen flow events exceeding any higher level of interest may be investigated without resorting to reanalysis of the historical data. The proposed methodology was applied to the daily hydrogen ion concentration flow records of Mersey River Watershed, N.S., Canada, which is affected by acid precipitation. Copyright (C) 1996 Elsevier Science Ltd https://portal.research.lu.se/en/publications/c25ee312-db61-4460-84ee-59bb6306123d Pergamon Press Ltd. 1996 eng Water Engineering 1873-7803 2595347 0029731436 10.1016/0098-3004(95)00102-6 http://dx.doi.org/10.1016/0098-3004(95)00102-6 yes 22 4 399 408 https://www.scopus.com/pages/publications/0029731436 c25ee312-db61-4460-84ee-59bb6306123d 2016-04-01T12:23:22+02:00 2025-10-14T10:21:21+02:00 2016-04-01T12:23:22+02:00 19 info:srw/schema/1/mods-v3.3xml journalArticle published yes 3 Anna Stromberg author Ulf Dahlstrom author Bengt Fridlund author 6933a8ca-9192-4770-914a-23c8067ee1f8 Department of Health Sciences v1000411 department Objective: To evaluate the effects of a single-session, interactive computer-based educational program on knowledge, compliance and quality of life in heart failure patients with special emphasis on gender differences. Methods: One hundred and fifty-four patients, mean age 70 years, from five heart failure clinics were randomised to either receiving only standard education (n = 72) or standard education and additional computer-based education (n = 82). Results: Knowledge was increased in both groups after I month with a trend towards higher knowledge (P = 0.07) in the computer-based group. The increase in knowledge was significantly higher in the computer-based group after 6 months (P = 0.03). No differences were found between the groups with regard to compliance with treatment and self-care or quality of life. The women had significantly lower quality of life and did not improve after 6 months as the men did (P = 0.0001). Conclusion: Computer-based education gave increased knowledge about heart failure. Practice implications: Computers can be a useful too] in heart failure education, but to improve compliance a single-session educational intervention is not sufficient. Gender differences in learning and quality of life should be further evaluated. (c) 2005 Elsevier Ireland Ltd. All rights reserved. https://portal.research.lu.se/en/publications/de609aa5-33ed-442f-a0cf-59d62e829f33 Elsevier 2006 eng compliance nursing self-care intervention patient education heart failure computer-based education quality of life knowledge gender Health Sciences 0738-3991 681447 000243012600016 33751080118 10.1016/j.pec.2005.12.007 http://dx.doi.org/10.1016/j.pec.2005.12.007 yes 64 1-3 128 135 https://www.scopus.com/pages/publications/33751080118 The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Nursing (Closed 2012) (013065000) de609aa5-33ed-442f-a0cf-59d62e829f33 2016-04-01T12:30:07+02:00 2025-10-14T11:34:58+02:00 2016-04-01T12:30:07+02:00 20 1.1title=computer* and title &lt;&gt; gamesandtitle=computer*title<>games