Congenital Anomalies and Childhood Celiac Disease: A Swedish Register-based Study.
Wingren, Carl Johan; Agardh, Daniel; Merlo, Juan (2012). Congenital Anomalies and Childhood Celiac Disease: A Swedish Register-based Study.. Journal of Pediatric Gastroenterology and Nutrition - Jpgn, 55, (6), 736 - 739
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Published
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English
Authors:
Wingren, Carl Johan
;
Agardh, Daniel
;
Merlo, Juan
Department:
Social Epidemiology
Celiac Disease and Diabetes Unit
EXODIAB: Excellence of Diabetes Research in Sweden
EpiHealth: Epidemiology for Health
Research Group:
Social Epidemiology
Celiac Disease and Diabetes Unit
Abstract:
Previously, chromosomal anomalies, and to a lesser extent, other congenital anomalies have been associated with an increased risk of celiac disease (CD). We investigated these associations using a systematic approach. We identified all singleton children (792,401) born in Sweden between 1987 and 1993, and obtained cases of CD using the Swedish National Inpatient Registry. We applied COX regression models as well as sibling designs to study the association between congenital anomalies and childhood CD. We observed that anomalies of either face, neck, ear, heart, digestive tract or of chromosomes were associated with CD.
Keywords:
child ;
celiac disease ;
congenital abnormalities ;
epidemiology ;
heart ;
diseases ;
risk factors
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