Structure of <i>Bombyx mori</i> chemosensory protein 1 in solution
Jansen, Severine; Chmelik, Josef; Zidek, Lukas; Padrta, Petr, et al. (2007). Structure of <i>Bombyx mori</i> chemosensory protein 1 in solution. Archives of Insect Biochemistry and Physiology, 66, (3), 135 - 145
|
Published
|
English
Authors:
Jansen, Severine
;
Chmelik, Josef
;
Zidek, Lukas
;
Padrta, Petr
, et al.
Department:
Department of Biology
Functional zoology
Pheromone Group
Project:
Evolutionary mechanisms of pheromone divergence in Lepidoptera
Research Group:
Pheromone Group
Abstract:
Chemosensory Proteins (CSPs) represent a family of conserved proteins found in insects that may be involved in chemosensory functions. BmorCSP1 is expressed mainly in antennae and legs of the silkworm moth Bombyx morii and was cloned from antennal cDNA. Here we report the determination of the structure of Bombyx mori CSP1 (BmorCSP1) by NMR. The overall fold of BmorCSP1 is globular and comprises six a-helices. These helices span residues 10-14, 17-27, 35-49, 57-72, 75-85, and 92-100. The internal hydrophobic sides of the helices are formed mostly by leucine and isoleucine residues and, therefore, well suited to constitute a binding site for hydrophobic ligands.
Keywords:
Bombyx mori ;
chemosensory proteins ;
NMR ;
Zoology ;
Biological Sciences
Cite this