A Mathematical Model of The Atrioventricular Node during Atrial Fibrillation
Corino, Valentina D.A.; Sandberg, Frida; Mainardi, Luca T.; Sörnmo, Leif (2010). A Mathematical Model of The Atrioventricular Node during Atrial Fibrillation [Host publication title missing], 37,, 117 - 120. Computing in Cardiology 2010. Ireland
Conference Proceeding/Paper
|
Published
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English
Authors:
Corino, Valentina D.A.
;
Sandberg, Frida
;
Mainardi, Luca T.
;
Sörnmo, Leif
Department:
Department of Electrical and Information Technology
Signal Processing-lup-obsolete
Research Group:
Signal Processing-lup-obsolete
Abstract:
The atrioventricular (AV) node plays a crucial role during
atrial fibrillation (AF). The aim of this study is to
present an AV node model which can be fitted to short-term
ECG recordings in order to infer certain AV node characteristics.
The proposed model is characterized by: i) the
arrival rate of atrial impulses; ii) two different refractory
periods, corresponding to dual AV nodal paths; iii) the
probability of an atrial impulse choosing either of these
pathways; iv) a parameter modeling prolongation of the
refractory period due to different physiological reasons.
The model was tested on atrial fibrillatory ECGs recorded
from 33 patients; the average normalized absolute error
between the normalized RR histogram and the estimated
model probability density function was 0.0023 ± 0.0016,
(20-ms bin size, 0–2 s interval). These preliminary results
are encouraging as AV nodal properties can be noninvasively
assessed by a set of statistical parameters with a
simple electrophysiological interpretation.
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