Lund University Publications
https://lup.lub.lu.se/search
Lund University Lund University Publications
2000-01-01T00:00+00:00
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Nanoplastics in aquatic environments—Sources, sampling techniques, and identification methods
https://lup.lub.lu.se/search/publication/0a522474-9599-4989-b818-74946bfd17e5
Zeng, Eddy Y.
Mattsson, Karin
Jocic, Simonne
de Lima, Juliana Aristéia
Hansson, Lars Anders
Gondikas, Andreas
2024
Since the industrial revolution, humans have extensively been contributing to the accumulation of rubble in marine and freshwater ecosystems. Because the buildup of trash in water bodies was previously considered miniscule owing to its capacity to drift away from vantage points, the growing impact of plastic pollutants has historically been neglected. Today, however, pollution of aquatic systems is recognized as one of the biggest environmental threats to our planet. Ever since the mass production of plastic material in the 1940s, plastic has been statistically the largest contributor to marine pollution (Ryan et al., 2009). Concerns have been raised about the ecotoxicology of not only the macroform of plastic but also more recently plastic degradation products, namely micro- and nanosized plastic particles. Anthropogenic particles are manufactured particles and particles produced by human activities. Microlitter consists of anthropogenic particles in the size range of 1μm to 5mm. Microplastics, a subcategory of microlitter, include particles between 1 and 1000μm in size and have a chemical composition of synthetic polymers, semisynthetic or copolymers, including tire and road wear particles. Furthermore, another property of microplastics is that they are solid state and insoluble at 20°C (Hartmann et al., 2019). Nanoplastics are the same type of particles as microplastics but in smaller sizes, namely between 1 and 1000nm. Engineered nanoparticles are commonly defined as nanosized particles with at least two dimensions below 100nm (Klaine et al., 2008). This chapter highlights nanoplastics in the aquatic environment; sources, sampling methods, and analytical techniques to identify nanoplastic particles in the aquatic environment.
https://lup.lub.lu.se/record/0a522474-9599-4989-b818-74946bfd17e5
http://dx.doi.org/10.1016/B978-0-443-15332-7.00003-X
ISBN: 9780443153334
ISBN: 9780443153327
scopus:85184105361
eng
Environmental Sciences
Analytical methods
Aquatic environment
Degradation
Fragmentation
Marine environment
Nanoplastic
Nanoplastics in aquatic environments—Sources, sampling techniques, and identification methods
contributiontobookanthology/chapter
info:eu-repo/semantics/bookPart
text
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Comparable survival in rats with intracranial glioblastoma irradiated with single-fraction conventional radiotherapy or FLASH radiotherapy
https://lup.lub.lu.se/search/publication/c3a8d4aa-8a5a-4aa7-a3bf-f9dbffa50190
Liljedahl, Emma
Konradsson, Elise
Linderfalk, Karin
Gustafsson, Emma
Petersson, Kristoffer
Ceberg, Crister
Redebrandt, Henrietta Nittby
2023
Background: Radiotherapy increases survival in patients with glioblastoma. However, the prescribed dose is limited by unwanted side effects on normal tissue. Previous experimental studies have shown that FLASH radiotherapy (FLASH-RT) can reduce these side effects. Still, it is important to establish an equal anti-tumor efficacy comparing FLASH-RT to conventional radiotherapy (CONV-RT). Methods: Fully immunocompetent Fischer 344 rats with the GFP-positive NS1 intracranial glioblastoma model were irradiated with CONV-RT or FLASH-RT in one fraction of 20 Gy, 25 Gy or 30 Gy. Animals were monitored for survival and acute dermal side effects. The brains were harvested upon euthanasia and tumors were examined post mortem. Results: Survival was significantly increased in animals irradiated with CONV-RT and FLASH-RT at 20 Gy and 25 Gy compared to control animals. The longest survival was reached in animals irradiated with FLASH-RT and CONV-RT at 25 Gy. Irradiation at 30 Gy did not lead to increased survival, despite smaller tumors. Tumor size correlated inversely with irradiation dose, both in animals treated with CONV-RT and FLASH-RT. Acute dermal side effects were mild, but only a small proportion of the animals were alive for evaluation of those side effects. Conclusion: The dose response was similar for CONV-RT and FLASH-RT in the present model. Tumor size upon the time of euthanasia correlated inversely with the irradiation dose.
https://lup.lub.lu.se/record/c3a8d4aa-8a5a-4aa7-a3bf-f9dbffa50190
http://dx.doi.org/10.3389/fonc.2023.1309174
scopus:85184236140
pmid:38322292
eng
Frontiers in Oncology; 13, no 1309174 (2023)
ISSN: 2234-943X
Cancer and Oncology
CONV-RT
FLASH-RT
glioblastoma
rat model
tumor size
Comparable survival in rats with intracranial glioblastoma irradiated with single-fraction conventional radiotherapy or FLASH radiotherapy
contributiontojournal/article
info:eu-repo/semantics/article
text
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Ferrous and ferric complexes with cyclometalating N-heterocyclic carbene ligands : a case of dual emission revisited
https://lup.lub.lu.se/search/publication/670484e8-78a7-44d6-9b05-9b17561dbfba
Johnson, Catherine Ellen
Schwarz, Jesper
Deegbey, Mawuli
Prakash, Om
Sharma, Kumkum
Huang, Ping
Ericsson, Tore
Häggström, Lennart
Bendix, Jesper
Gupta, Arvind Kumar
Jakubikova, Elena
Wärnmark, Kenneth
Lomoth, Reiner
2023-08-29
Iron N-heterocyclic carbene (FeNHC) complexes with long-lived charge transfer states are emerging as a promising class of photoactive materials. We have synthesized [FeII(ImP)2] (ImP = bis(2,6-bis(3-methylimidazol-2-ylidene-1-yl)phenylene)) that combines carbene ligands with cyclometalation for additionally improved ligand field strength. The 9 ps lifetime of its 3MLCT (metal-to-ligand charge transfer) state however reveals no benefit from cyclometalation compared to Fe(ii) complexes with NHC/pyridine or pure NHC ligand sets. In acetonitrile solution, the Fe(ii) complex forms a photoproduct that features emission characteristics (450 nm, 5.1 ns) that were previously attributed to a higher (2MLCT) state of its Fe(iii) analogue [FeIII(ImP)2]+, which led to a claim of dual (MLCT and LMCT) emission. Revisiting the photophysics of [FeIII(ImP)2]+, we confirmed however that higher (2MLCT) states of [FeIII(ImP)2]+ are short-lived (<10 ps) and therefore, in contrast to the previous interpretation, cannot give rise to emission on the nanosecond timescale. Accordingly, pristine [FeIII(ImP)2]+ prepared by us only shows red emission from its lower 2LMCT state (740 nm, 240 ps). The long-lived, higher energy emission previously reported for [FeIII(ImP)2]+ is instead attributed to an impurity, most probably a photoproduct of the Fe(ii) precursor. The previously reported emission quenching on the nanosecond time scale hence does not support any excited state reactivity of [FeIII(ImP)2]+ itself.
https://lup.lub.lu.se/record/670484e8-78a7-44d6-9b05-9b17561dbfba
http://dx.doi.org/10.1039/d3sc02806b
scopus:85171463916
pmid:37772113
eng
Chemical Science; 14(37), pp 10129-10139 (2023)
ISSN: 2041-6520
Physical Chemistry
Ferrous and ferric complexes with cyclometalating N-heterocyclic carbene ligands : a case of dual emission revisited
contributiontojournal/article
info:eu-repo/semantics/article
text
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Free-Energy Landscape and Rate Estimation of the Aromatic Ring Flips in Basic Pancreatic Trypsin Inhibitors Using Metadynamics
https://lup.lub.lu.se/search/publication/df5f9ede-08bf-4841-a453-51d36d7cdab8
Kulkarni, Mandar
Söderhjelm, Pär
2023-10-10
Aromatic side chains (phenylalanine and tyrosine) of a protein flip by 180° around the Cβ-Cγ axis (χ2 dihedral of the side chain), producing two symmetry-equivalent states. The study of ring flip dynamics with nuclear magnetic resonance (NMR) experiments helps to understand local conformational fluctuations. Ring flips are categorized as slow (milliseconds and onward) or fast (nanoseconds to near milliseconds) based on timescales accessible to NMR experiments. In this study, we investigated the ability of the infrequent metadynamics approach to estimate the flip rate and discriminate between slow and fast ring flips for eight individual aromatic side chains (F4, Y10, Y21, F22, Y23, F33, Y35, and F45) of the basic pancreatic trypsin inhibitor. Well-tempered metadynamics simulations were performed to estimate the ring-flipping free-energy surfaces for all eight aromatic residues. The results indicate that χ2 as a standalone collective variable (CV) is not sufficient to obtain computationally consistent results. Inclusion of a complementary CV, such as χ1(Cα-Cβ), solved the problem for most residues and enabled us to classify fast and slow ring flips. This indicates the importance of librational motions in ring flips. Multiple pathways and mechanisms were observed for residues F4, Y10, and F22. Recrossing events were observed for residues F22 and F33, indicating a possible role of friction effects in ring flipping. The results demonstrate the successful application of infrequent metadynamics to estimate ring flip rates and identify certain limitations of the approach.
https://lup.lub.lu.se/record/df5f9ede-08bf-4841-a453-51d36d7cdab8
http://dx.doi.org/10.1021/acs.jctc.3c00460
scopus:85172918450
pmid:37698852
eng
Journal of Chemical Theory and Computation; 19(19), pp 6605-6618 (2023)
ISSN: 1549-9618
Biophysics
Theoretical Chemistry
Free-Energy Landscape and Rate Estimation of the Aromatic Ring Flips in Basic Pancreatic Trypsin Inhibitors Using Metadynamics
contributiontojournal/article
info:eu-repo/semantics/article
text
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Interaction of nanoparticles with lipid films : The role of symmetry and shape anisotropy
https://lup.lub.lu.se/search/publication/9a964c39-fa48-4405-b2d6-193aba81ef31
Caselli, Lucrezia
Ridolfi, Andrea
Mangiapia, Gaetano
Maltoni, Pierfrancesco
Moulin, Jean François
Berti, Debora
Steinke, Nina Juliane
Gustafsson, Emil
Nylander, Tommy
Montis, Costanza
2022-02-07
The bioactivity, biological fate and cytotoxicity of nanomaterials when they come into contact with living organisms are determined by their interaction with biomacromolecules and biological barriers. In this context, the role of symmetry/shape anisotropy of both the nanomaterials and biological interfaces in their mutual interaction, is a relatively unaddressed issue. Here, we study the interaction of gold nanoparticles (NPs) of different shapes (nanospheres and nanorods) with biomimetic membranes of different morphology, i.e. flat membranes (2D symmetry, representative of the most common plasma membrane geometry), and cubic membranes (3D symmetry, representative of non-lamellar membranes, found in Nature under certain biological conditions). For this purpose we used an ensemble of complementary structural techniques, including Neutron Reflectometry, Grazing Incidence Small-Angle Neutron Scattering, on a nanometer lengthscale and Confocal Laser Scanning Microscopy on a micrometer length scale. We found that the structural stability of the membrane towards NPs is dependent on the topological characteristic of the lipid assembly and of the NPs, where a higher symmetry gave higher stability. In addition, Confocal Laser Scanning Microscopy analyses highlighted that NPs interact with cubic and lamellar phases according to two distinct mechanisms, related to the different structures of the lipid assemblies. This study for the first time systematically addresses the role of NPs shape in the interaction with lipid assemblies with different symmetry. The results will contribute to improve the fundamental knowledge on lipid interfaces and will provide new insights on the biological function of phase transitions as a response strategy to the exposure of NPs. This journal is
https://lup.lub.lu.se/record/9a964c39-fa48-4405-b2d6-193aba81ef31
http://dx.doi.org/10.1039/d1cp03201a
pmid:34647947
scopus:85123973708
eng
Physical Chemistry Chemical Physics; 24(5), pp 2762-2776 (2022)
ISSN: 1463-9076
Physical Chemistry
Interaction of nanoparticles with lipid films : The role of symmetry and shape anisotropy
contributiontojournal/article
info:eu-repo/semantics/article
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Release of moth pheromone compounds from <i>Nicotiana benthamiana</i> upon transient expression of heterologous biosynthetic genes
https://lup.lub.lu.se/search/publication/fb3e0c95-5111-4052-bb22-bb8d36f28d26
Xia, Yi Han
Ding, Bao Jian
Dong, Shuang Lin
Wang, Hong Lei
Hofvander, Per
Löfstedt, Christer
2022-03-31
Background: Using genetically modified plants as natural dispensers of insect pheromones may eventually become part of a novel strategy for integrated pest management. Results: In the present study, we first characterized essential functional genes for sex pheromone biosynthesis in the rice stem borer Chilo suppressalis (Walker) by heterologous expression in Saccharomyces cerevisiae and Nicotiana benthamiana, including two desaturase genes CsupYPAQ and CsupKPSE and a reductase gene CsupFAR2. Subsequently, we co-expressed CsupYPAQ and CsupFAR2 together with the previously characterized moth desaturase Atr∆11 in N. benthamiana. This resulted in the production of (Z)-11-hexadecenol together with (Z)-11-hexadecenal, the major pheromone component of C. suppressalis. Both compounds were collected from the transformed N. benthamiana headspace volatiles using solid-phase microextraction. We finally added the expression of a yeast acetyltransferase gene ATF1 and could then confirm also (Z)-11-hexadecenyl acetate release from the plant. Conclusions: Our results pave the way for stable transformation of plants to be used as biological pheromone sources in different pest control strategies.
https://lup.lub.lu.se/record/fb3e0c95-5111-4052-bb22-bb8d36f28d26
http://dx.doi.org/10.1186/s12915-022-01281-8
pmid:35361182
scopus:85127377773
eng
BMC Biology; 20(1), pp 1-18 (2022)
ISSN: 1741-7007
Biochemistry and Molecular Biology
Zoology
Acetyltransferase
Alcohol oxidation
Fatty acyl desaturases
Fatty acyl reductase
Functional characterization
Heterologous expression systems
Pheromone-releasing plants
Release of moth pheromone compounds from Nicotiana benthamiana upon transient expression of heterologous biosynthetic genes
contributiontojournal/article
info:eu-repo/semantics/article
text
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Charge photogeneration dynamics in non-fullerene polymer solar cells with fluorinated and non-fluorinated acceptors
https://lup.lub.lu.se/search/publication/73df0285-9cb5-40b6-b5a5-c6a202f9c45d
Cai, Zekai
Hu, Rong
Xiao, Zijie
Feng, Junyi
Zou, Xianshao
Wen, Guanzhao
Dong, Geng
Zhang, Wei
2024-02-21
In this work, charge photogeneration and recombination processes of PM6:IDIC-4F and PM6:IDIC blend films were investigated by the steady-state and time-resolved spectroscopies, as well as the time-dependent density functional theory calculations. The peaks in absorption and photoluminescence (PL) spectra of IDIC and IDIC-4F solutions were assigned by combining the experiment and the simulation of UV-vis absorption and PL spectra. For neat acceptor films, the exciton diffusion length of neat IDIC and IDIC-4F films was estimated as ∼28.9 and ∼19.9 nm, respectively. For PM6-based blend films, we find that the fluorine substitution engineering on the IDIC acceptor material can increase the phase separate size of acceptor material in blend films, resulting in the reduction of dissociation efficiencies of acceptor excitons. In addition, we find that the charge recombination in PM6:IDIC-4F is dominated by bimolecular recombination, in comparison to geminate type carrier recombination in PM6:IDIC blend films. In addition, we find that thermal annealing treatment has a weak influence on carrier recombination but slightly reduces the exciton dissociation efficiency of acceptor in PM6:IDIC blend films, leading to a slightly reduced power conversion efficiency of PM6:IDIC solar cells. These results may shed light on the design of high-performance semiconductor molecules for application in solar cells.
https://lup.lub.lu.se/record/73df0285-9cb5-40b6-b5a5-c6a202f9c45d
http://dx.doi.org/10.1063/5.0177876
scopus:85185344450
pmid:38364001
eng
Journal of Chemical Physics; 160(7), no 074702 (2024)
ISSN: 0021-9606
Atom and Molecular Physics and Optics
Theoretical Chemistry
Charge photogeneration dynamics in non-fullerene polymer solar cells with fluorinated and non-fluorinated acceptors
contributiontojournal/article
info:eu-repo/semantics/article
text
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Environmental assessment of diets : overview and guidance on indicator choice
https://lup.lub.lu.se/search/publication/4c98bc54-1169-49a8-b135-21b37f9b23c1
Ran, Ylva
Cederberg, Christel
Jonell, Malin
Bergman, Kristina
De Boer, Imke J.M.
Einarsson, Rasmus
Karlsson, Johan
Potter, Hanna Karlsson
Martin, Michael
Metson, Geneviève S.
Nemecek, Thomas
Nicholas, Kimberly A.
Strand, Åsa
Tidåker, Pernilla
Van der Werf, Hayo
Vanham, Davy
Van Zanten, Hannah H.E.
Verones, Francesca
Röös, Elin
2024-03
Comprehensive but interpretable assessment of the environmental performance of diets involves choosing a set of appropriate indicators. Current knowledge and data gaps on the origin of dietary foodstuffs restrict use of indicators relying on site-specific information. This Personal View summarises commonly used indicators for assessing the environmental performance of diets, briefly outlines their benefits and drawbacks, and provides recommendations on indicator choices for actors across multiple fields involved in activities that include the environmental assessment of diets. We then provide recommendations on indicator choices for actors across multiple fields involved in activities that use environmental assessments, such as health and nutrition experts, policy makers, decision makers, and private-sector and public-sector sustainability officers. We recommend that environmental assessment of diets should include indicators for at least the five following areas: climate change, biosphere integrity, blue water consumption, novel entities, and impacts on natural resources (especially wild fish stocks), to capture important environmental trade-offs. If more indicators can be handled in the assessment, indicators to capture impacts related to land use quantity and quality and green water consumption should be used. For ambitious assessments, indicators related to biogeochemical flows, stratospheric ozone depletion, and energy use can be added.
https://lup.lub.lu.se/record/4c98bc54-1169-49a8-b135-21b37f9b23c1
http://dx.doi.org/10.1016/S2542-5196(24)00006-8
scopus:85186732178
pmid:38453383
eng
The Lancet Planetary Health; 8(3), pp 172-187 (2024)
ISSN: 2542-5196
Environmental Sciences
Environmental assessment of diets : overview and guidance on indicator choice
contributiontojournal/systematicreview
info:eu-repo/semantics/article
text
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Search for New Phenomena in Two-Body Invariant Mass Distributions Using Unsupervised Machine Learning for Anomaly Detection at √s = 13 TeV with the ATLAS Detector
https://lup.lub.lu.se/search/publication/f0f650f1-831f-4456-adac-b898d2580c3b
Aad, G.
Åkesson, T.P.A.
Corrigan, E.E.
Doglioni, C.
Geisen, J.
Hansen, E.
Hedberg, V.
Herde, Hannah
Konya, B.
Lytken, E.
Poettgen, R.
Simpson, N.D.
Smirnova, O.
Zwalinski, L.
2024
Searches for new resonances are performed using an unsupervised anomaly-detection technique. Events with at least one electron or muon are selected from 140 fb−1 of pp collisions at √s ¼ 13 TeV recorded by ATLAS at the Large Hadron Collider. The approach involves training an autoencoder on data, and subsequently defining anomalous regions based on the reconstruction loss of the decoder. Studies focus on nine invariant mass spectra that contain pairs of objects consisting of one light jet or b jet and either one lepton (e; μ), photon, or second light jet or b jet in the anomalous regions. No significant deviations from the background hypotheses are observed. Limits on contributions from generic Gaussian signals with various widths of the resonance mass are obtained for nine invariant masses in the anomalous regions. © 2024 CERN, for the ATLAS Collaboration.
https://lup.lub.lu.se/record/f0f650f1-831f-4456-adac-b898d2580c3b
http://dx.doi.org/10.1103/PhysRevLett.132.081801
scopus:85186742137
pmid:38457710
eng
Physical Review Letters; 132(8), no 081801 (2024)
ISSN: 0031-9007
Subatomic Physics
Anomaly detection
Machine learning
Tellurium compounds
Anomalous regions
ATLAS detectors
Auto encoders
Invariant mass distribution
Large Hadron Collider
Large-hadron colliders
Region-based
Unsupervised anomaly detection
Unsupervised machine learning
Mass spectrometry
Search for New Phenomena in Two-Body Invariant Mass Distributions Using Unsupervised Machine Learning for Anomaly Detection at √s = 13 TeV with the ATLAS Detector
contributiontojournal/article
info:eu-repo/semantics/article
text
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Enhanced Production of Λb0 Baryons in High-Multiplicity pp Collisions at s =13 TeV
https://lup.lub.lu.se/search/publication/4a81f8be-4e52-4703-a7ba-2f003d05344f
Aaij, R.
Ruiz-Vidal, Joan
Zunica, G.
2024
The production rate of Λb0 baryons relative to B0 mesons in pp collisions at a center-of-mass energy s=13 TeV is measured by the LHCb experiment. The ratio of Λb0 to B0 production cross sections shows a significant dependence on both the transverse momentum and the measured charged-particle multiplicity. At low multiplicity, the ratio measured at LHCb is consistent with the value measured in e+e- collisions, and increases by a factor of ∼2 with increasing multiplicity. At relatively low transverse momentum, the ratio of Λb0 to B0 cross sections is higher than what is measured in e+e- collisions, but converges with the e+e- ratio as the momentum increases. These results imply that the evolution of heavy b quarks into final-state hadrons is influenced by the density of the hadronic environment produced in the collision. Comparisons with several models and implications for the mechanisms enforcing quark confinement are discussed. © 2024 CERN.
https://lup.lub.lu.se/record/4a81f8be-4e52-4703-a7ba-2f003d05344f
http://dx.doi.org/10.1103/PhysRevLett.132.081901
scopus:85185840573
pmid:38457697
eng
Physical Review Letters; 132(8), no 081901 (2024)
ISSN: 1079-7114
Subatomic Physics
Hadrons
Momentum
Tellurium compounds
A-center
Center-of-mass energies
Centre-of-mass energies
Charged particle multiplicities
Final state
Hadronics
High multiplicity
Production cross section
Production rates
Transverse momenta
article
baryon
Charged particles
Enhanced Production of Λb0 Baryons in High-Multiplicity pp Collisions at s =13 TeV
contributiontojournal/article
info:eu-repo/semantics/article
text
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The genome sequence of the Brown Argus, Aricia agestis (Denis & Schiffermüller, 1775)
https://lup.lub.lu.se/search/publication/196a55ff-5d03-4283-8678-af7c25744cef
Hayward, Alex
Lohse, Konrad
Vila, Roger
Laetsch, Dominik R.
Hedlund, Johanna S.U.
2023
We present genome assemblies from two male Aricia agestis specimens (the Brown Argus; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The genome sequences are 435.3 and 437.4 megabases in span. Each assembly is scaffolded into 23 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genomes were assembled and are 15.47 and 15.45 kilobases in length. Gene annotation of these assemblies on Ensembl identified 12,688 and 12,654 protein coding genes.
https://lup.lub.lu.se/record/196a55ff-5d03-4283-8678-af7c25744cef
http://dx.doi.org/10.12688/wellcomeopenres.19784.1
pmid:38404635
scopus:85186896009
eng
Wellcome Open Research; 8, no 336 (2023)
ISSN: 2398-502X
Genetics
Aricia agestis
Brown Argus
chromosomal
genome sequence
Lepidoptera
The genome sequence of the Brown Argus, Aricia agestis (Denis & Schiffermüller, 1775)
contributiontojournal/article
info:eu-repo/semantics/article
text
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Animal migration in the Anthropocene : threats and mitigation options
https://lup.lub.lu.se/search/publication/04c0bb29-8038-4808-8031-866767108892
Cooke, Steven J.
Piczak, Morgan L.
Singh, Navinder J.
Åkesson, Susanne
Ford, Adam T.
Chowdhury, Shawan
Mitchell, Greg W.
Norris, D. Ryan
Hardesty-Moore, Molly
McCauley, Douglas
Hammerschlag, Neil
Tucker, Marlee A.
Horns, Joshua J.
Reisinger, Ryan R.
Kubelka, Vojtěch
Lennox, Robert J.
2024
Animal migration has fascinated scientists and the public alike for centuries, yet migratory animals are facing diverse threats that could lead to their demise. The Anthropocene is characterised by the reality that humans are the dominant force on Earth, having manifold negative effects on biodiversity and ecosystem function. Considerable research focus has been given to assessing anthropogenic impacts on the numerical abundance of species/populations, whereas relatively less attention has been devoted to animal migration. However, there are clear linkages, for example, where human-driven impacts on migration behaviour can lead to population/species declines or even extinction. Here, we explore anthropogenic threats to migratory animals (in all domains – aquatic, terrestrial, and aerial) using International Union for the Conservation of Nature (IUCN) Threat Taxonomy classifications. We reveal the diverse threats (e.g. human development, disease, invasive species, climate change, exploitation, pollution) that impact migratory wildlife in varied ways spanning taxa, life stages and type of impact (e.g. from direct mortality to changes in behaviour, health, and physiology). Notably, these threats often interact in complex and unpredictable ways to the detriment of wildlife, further complicating management. Fortunately, we are beginning to identify strategies for conserving and managing migratory animals in the Anthropocene. We provide a set of strategies that, if embraced, have the potential to ensure that migratory animals, and the important ecological functions sustained by migration, persist.
https://lup.lub.lu.se/record/04c0bb29-8038-4808-8031-866767108892
http://dx.doi.org/10.1111/brv.13066
pmid:38437713
scopus:85186909601
eng
Biological Reviews; (2024)
ISSN: 1464-7931
Ecology
animal movement
biodiversity
conservation
natural resources management
phenology
wildlife biology
Animal migration in the Anthropocene : threats and mitigation options
contributiontojournal/article
info:eu-repo/semantics/article
text
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Molecular imprinting on the nanoscale rapid detection of cells
https://lup.lub.lu.se/search/publication/1b114b6e-2f24-4ef4-89f4-db6f7a8d9519
Idil, Neslihan
Aslıyüce, Sevgi
Perçin, Işık
Mattiasson, Bo
2023
In the last 30 years, molecular imprinting has been evidenced as a desirable approach to design artificial, specific, and selective recognition sites for the target molecules/cells. Molecularly imprinted polymers (MIPs) are the most encouraging reflection of the advanced area of biomimetics and have attracted important popularity for the detection of many types of molecules including peptides, proteins, and even cells. In this context, imprinting of relatively small molecules is well identified; however, imprinting of cells still remains a big challenge from past to present. In this chapter, the importance of molecular recognition mechanisms in the renovation of artificial regions was stated, and molecular imprinting strategies used for cell detection were presented. In this respect, cell lithography, epitope imprinting, whole-cell imprinting technology involving cell-mediated lithography, and microcontact imprinting approaches were explained. The applications of nanoparticles, quantum dots, sensing platforms, and imaging approaches within the extensive group of nano-MIPs were discussed in terms of microbial, viral, and mammalian cell detection. In conclusion, the challenges and future perspectives on the construction of nano-MIPs aiming for cell detection were outlined.
https://lup.lub.lu.se/record/1b114b6e-2f24-4ef4-89f4-db6f7a8d9519
http://dx.doi.org/10.1016/B978-0-443-15359-4.00012-7
ISBN: 9780443153594
ISBN: 9780443153600
scopus:85179244697
eng
Biochemistry and Molecular Biology
cell detection
Molecular imprinting
nanosized materials
sensing
Molecular imprinting on the nanoscale rapid detection of cells
contributiontobookanthology/chapter
info:eu-repo/semantics/bookPart
text
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Widespread Pesticide Distribution in the European Atmosphere Questions their Degradability in Air
https://lup.lub.lu.se/search/publication/869a8d1e-14c7-44ee-bbb7-dc6030508f9f
Mayer, Ludovic
Degrendele, Céline
Šenk, Petr
Kohoutek, Jiři
Přibylová, Petra
Kukučka, Petr
Melymuk, Lisa
Durand, Amandine
Ravier, Sylvain
Alastuey, Andres
Baker, Alex R.
Baltensperger, Urs
Baumann-Stanzer, Kathrin
Biermann, Tobias
Bohlin-Nizzetto, Pernilla
Ceburnis, Darius
Conil, Sébastien
Couret, Cédric
Degórska, Anna
Diapouli, Evangelia
Eckhardt, Sabine
Eleftheriadis, Konstantinos
Forster, Grant L.
Freier, Korbinian
Gheusi, François
Gini, Maria I.
Hellén, Heidi
Henne, Stephan
Herrmann, Hartmut
Holubová Šmejkalová, Adéla
Hõrrak, Urmas
Hüglin, Christoph
Junninen, Heikki
Kristensson, Adam
Langrene, Laurent
Levula, Janne
Lothon, Marie
Ludewig, Elke
Makkonen, Ulla
Matejovičová, Jana
Mihalopoulos, Nikolaos
Mináriková, Veronika
Moche, Wolfgang
Noe, Steffen M.
Pérez, Noemí
Petäjä, Tuukka
Pont, Véronique
Poulain, Laurent
Quivet, Etienne
Ratz, Gabriela
Lammel, Gerhard
2024-02
Risk assessment of pesticide impacts on remote ecosystems makes use of model-estimated degradation in air. Recent studies suggest these degradation rates to be overestimated, questioning current pesticide regulation. Here, we investigated the concentrations of 76 pesticides in Europe at 29 rural, coastal, mountain, and polar sites during the agricultural application season. Overall, 58 pesticides were observed in the European atmosphere. Low spatial variation of 7 pesticides suggests continental-scale atmospheric dispersal. Based on concentrations in free tropospheric air and at Arctic sites, 22 pesticides were identified to be prone to long-range atmospheric transport, which included 15 substances approved for agricultural use in Europe and 7 banned ones. Comparison between concentrations at remote sites and those found at pesticide source areas suggests long atmospheric lifetimes of atrazine, cyprodinil, spiroxamine, tebuconazole, terbuthylazine, and thiacloprid. In general, our findings suggest that atmospheric transport and persistence of pesticides have been underestimated and that their risk assessment needs to be improved.
https://lup.lub.lu.se/record/869a8d1e-14c7-44ee-bbb7-dc6030508f9f
http://dx.doi.org/10.1021/acs.est.3c08488
pmid:38323876
scopus:85187303663
eng
Environmental Science and Technology; 58(7), pp 3342-3352 (2024)
ISSN: 0013-936X
Meteorology and Atmospheric Sciences
Environmental Sciences
atmosphere
Pesticide Distribution
pesticides
risk assessment
transport
air quality
Widespread Pesticide Distribution in the European Atmosphere Questions their Degradability in Air
contributiontojournal/article
info:eu-repo/semantics/article
text
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The DIRAC code for relativistic molecular calculations
https://lup.lub.lu.se/search/publication/1dd042c9-1888-4905-a998-2c9879c5e08c
Saue, Trond
Bast, Radovan
Gomes, André Severo Pereira
Jensen, Hans Jørgen Aa
Visscher, Lucas
Aucar, Ignacio Agustín
Di Remigio, Roberto
Dyall, Kenneth G.
Eliav, Ephraim
Fasshauer, Elke
Fleig, Timo
Halbert, Loïc
Hedegård, Erik Donovan
Helmich-Paris, Benjamin
Iliaš, Miroslav
Jacob, Christoph R.
Knecht, Stefan
Laerdahl, Jon K.
Vidal, Marta L.
Nayak, Malaya K.
Olejniczak, Małgorzata
Olsen, Jógvan Magnus Haugaard
Pernpointner, Markus
Senjean, Bruno
Shee, Avijit
Sunaga, Ayaki
van Stralen, Joost N.P.
2020-05-29
DIRAC is a freely distributed general-purpose program system for one-, two-, and four-component relativistic molecular calculations at the level of Hartree-Fock, Kohn-Sham (including range-separated theory), multiconfigurational self-consistent-field, multireference configuration interaction, electron propagator, and various flavors of coupled cluster theory. At the self-consistent-field level, a highly original scheme, based on quaternion algebra, is implemented for the treatment of both spatial and time reversal symmetry. DIRAC features a very general module for the calculation of molecular properties that to a large extent may be defined by the user and further analyzed through a powerful visualization module. It allows for the inclusion of environmental effects through three different classes of increasingly sophisticated embedding approaches: the implicit solvation polarizable continuum model, the explicit polarizable embedding model, and the frozen density embedding model.
https://lup.lub.lu.se/record/1dd042c9-1888-4905-a998-2c9879c5e08c
http://dx.doi.org/10.1063/5.0004844
pmid:32486677
scopus:85085909114
eng
The Journal of chemical physics; 152(20), pp 204104-204104 (2020)
ISSN: 0021-9606
Theoretical Chemistry
The DIRAC code for relativistic molecular calculations
contributiontojournal/article
info:eu-repo/semantics/article
text
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Storage, patterns, and environmental controls of soil organic carbon stocks in the permafrost regions of the Northern Hemisphere
https://lup.lub.lu.se/search/publication/36cff977-b684-4ef3-b9aa-4d2f6ac2cb30
Wu, Tonghua
Wang, Dong
Mu, Cuicui
Zhang, Wenxin
Zhu, Xiaofan
Zhao, Lin
Li, Ren
Hu, Guojie
Zou, Defu
Chen, Jie
Wei, Xianhua
Wen, Amin
Shang, Chengpeng
La, Yune
Lou, Peiqing
Ma, Xin
Wu, Xiaodong
2022-07-01
Large stocks of soil organic carbon (SOC) accumulated in the Northern Hemisphere permafrost regions may be vulnerable to climatic warming, but global estimates of SOC distribution and magnitude in permafrost regions still have large uncertainties. Based on multiple high-resolution environmental variables and a compiled soil sample dataset (>3000 soil profiles), we used machine-learning methods to estimate the size and spatial distribution of SOC for the top 3 m soils in the Northern Hemisphere permafrost regions. We also identified key environmental predictors of SOC. The results showed that the SOC storage for the top 3 m soil was 1079 ± 174 Pg C across the Northern Hemisphere permafrost regions (20.8 × 106 km2), including 1057 ± 167 Pg C in the northern permafrost regions and 22 ± 7 Pg C in the Third Pole permafrost regions. The mean annual air temperature and NDVI are the main controlling factors for the spatial distribution of SOC stocks in the northern and the Third Pole permafrost regions. Our estimations were more accurate than the existing global SOC stock maps. The results improve our understanding of the regional and global permafrost carbon cycle and their feedback to the climate system.
https://lup.lub.lu.se/record/36cff977-b684-4ef3-b9aa-4d2f6ac2cb30
http://dx.doi.org/10.1016/j.scitotenv.2022.154464
pmid:35278536
scopus:85126303370
eng
Science of the Total Environment; 828, no 154464 (2022)
ISSN: 0048-9697
Soil Science
Earth and Related Environmental Sciences
Machine learning
Northern Hemisphere
Permafrost
Soil organic carbon
Storage, patterns, and environmental controls of soil organic carbon stocks in the permafrost regions of the Northern Hemisphere
contributiontojournal/article
info:eu-repo/semantics/article
text
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Preclinical x-ray dark-field radiography for pulmonary emphysema evaluation
https://lup.lub.lu.se/search/publication/37129f15-7594-4e10-a595-ab46781fcea6
Yaroshenko, A.
Meinel, F. G.
Bech, M.
Tapfer, A.
Velroyen, A.
Schleede, S.
Muller, M.
Auweter, S.
Bohla, A.
Yildirim, A. O.
Nikolaou, K.
Bamberg, F.
Eickelberg, O.
Reiser, M.
Pfeiffer, F.
2013
Pulmonary emphysema is a widespread disorder characterized by irreversible destruction of alveolar walls. The spatial distribution of the disease, so far, could only be obtained using an x-ray CT scan, implying a high patient dose. X-ray scattering on alveolar structures is measured in the dark-field signal. The signal is dependent on the size of alveoli and therefore, a combination of absorption and dark-field signal is explored for mapping the distribution of emphysema in the lung on x-ray projection images. In this study three excised murine lungs with pulmonary emphysema and three control samples were imaged using a compact, cone-beam, small-animal x-ray dark-field scanner with a polychromatic source. Statistical analysis of the results, based on a combination of transmission and dark-field signals, revealed a distinct difference between emphysematous and control samples. Subsequently, the distribution of emphysema was mapped out per-pixel for the lungs and showed good agreement with histological findings.
https://lup.lub.lu.se/record/37129f15-7594-4e10-a595-ab46781fcea6
http://dx.doi.org/10.1109/ISBI.2013.6556489
ISBN: 978-1-4673-6455-3
ISBN: 978-1-4673-6456-0
scopus:84881620384
eng
Proceedings - International Symposium on Biomedical Imaging; pp 370-373 (2013)
ISSN: 1945-7928
ISSN: 1945-8452
Radiology, Nuclear Medicine and Medical Imaging
dark-field
emphysema
grating interferometer
phase-contrast
x-ray
Preclinical x-ray dark-field radiography for pulmonary emphysema evaluation
contributiontobookanthology/conference
info:eu-repo/semantics/conferencePaper
text