Haematologica
The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells
Niels Weinhold, Tobias Meissner, David C Johnson, Anja Seckinger, Jérôme Moreaux, Asta Försti, Bowang Chen, Jolanta Nickel, Daniel Chubb, Andrew C. Rawstron, Chi Doughty, Nasrin B. Dahir, Dil B. Begum, Kwee Young, Brian A. Walker, Per Hoffmann, Marcus M. Nöthen, Faith E. Davies, Bernard Klein, Hartmut Goldschmidt, Gareth J. Morgan, Richard S Houlston, Dirk Hose, Kari Hemminki
Haematologica March 2015 100: e110-e113; doi:10.3324/haematol.2014.118786

Author Affiliations

  1. Niels Weinhold1,*,
  2. Tobias Meissner1,2,*,
  3. David C Johnson3,*,
  4. Anja Seckinger1,
  5. Jérôme Moreaux4,
  6. Asta Försti5,6,
  7. Bowang Chen5,
  8. Jolanta Nickel1,
  9. Daniel Chubb7,
  10. Andrew C. Rawstron8,
  11. Chi Doughty8,
  12. Nasrin B. Dahir3,
  13. Dil B. Begum3,
  14. Kwee Young9,
  15. Brian A. Walker3,
  16. Per Hoffmann10,11,
  17. Marcus M. Nöthen10,12,
  18. Faith E. Davies3,
  19. Bernard Klein4,**,
  20. Hartmut Goldschmidt1,13,**,
  21. Gareth J. Morgan3,**,
  22. Richard S Houlston7,**,
  23. Dirk Hose1,13,**⇑ and
  24. Kari Hemminki5,6,**
  1. 1Department of Internal Medicine V, University of Heidelberg, Germany
  2. 2Department of Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
  3. 3Centre for Myeloma Research, Division of Molecular Pathology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK
  4. 4INSERM, Unité 1040, Institut de Recherche en Biothérapie, Centre Hospitalier Universitaire de Montpellier, Hôpital Saint Eloi, Avenue Augustin Fliche, 34295 Montpellier, France
  5. 5German Cancer Research Center, Heidelberg, Germany
  6. 6Center for Primary Health Care Research, Lund University, Malmo, Sweden
  7. 7Molecular and Population Genetics, Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK
  8. 8Haematological Malignancy Diagnostic Service Laboratory, St James University Hospital, Leeds, UK
  9. 9Department of Haematology, University College London Hospital, UK
  10. 10Institute of Human Genetics, University of Bonn, Germany
  11. 11Division of Medical Genetics, Department of Biomedicine, University of Basel, Switzerland
  12. 12Department of Genomics, Life & Brain Center, University of Bonn, Germany
  13. 13National Centre for Tumor Diseases, Heidelberg, Germany
  1. Correspondence: dirk.hose{at}med.uni-heidelberg.de
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Keywords

multiple myeloma
risk
single nucleotide polymorphism
eQTL
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