Hakon Leffler
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- 2011
- The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins.
- Inhibition of Galectins with Small Molecules
- Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors
- 2010
- 1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors
- Copper-Free Huisgen 1,3-Dipolar Cycloaddition to 3-Benzotriazolo-3-Deoxy-β-D-Galactopyranosides – Cyclization of a Secondary Azide and Benzyne
- Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
- Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3.
- Multimeric Lactoside "Click Clusters" as Tools to Investigate the Effect of Linker Length in Specific Interactions with Peanut Lectin, Galectin-1, and-3
- Essential role of galectin3 in reducing the severity of S. aureus-induced arthritis in mice
- Galectin-3, a marker for vacuole lysis by invasive pathogens
- Monovalent Interactions of Galectin-1
- Mutational tuning of galectin-3 specificity and biological function.
- The inflammatory mediator galectin-3 is bound to phagocytes in circulation
- 2009
- Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3
- Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils