@article{06a121f3-d614-422a-bc4d-9198095310ac,
  abstract     = {{<p>Aims Left ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was therefore to investigate how the four-chambered heart responds to exercise in ET and UT healthy individuals using exercise real-time cardiac magnetic resonance imaging (CMR) while controlling for effects of respiration. Materials and methods Twenty ET (9 women) and 13 UT healthy individuals matched for age and sex underwent CMR at rest and during moderate and vigorous exercise. LV and RV end-diastolic and end-systolic volumes (EDV and ESV), stroke volumes (SV) and maximal and minimal LA and RA volumes (LAV<sub>max</sub>, RAV<sub>max</sub> and LAV<sub>min</sub>, RAV<sub>min</sub>) were measured at end expiration. Results LVEDV and LVESV decreased during exercise in both groups. RVEDV and RVESV decreased during exercise in ET but was unchanged in UT. LAV<sub>max</sub> and LAV<sub>min</sub> were unchanged from rest to vigorous exercise in both groups. RAV<sub>max</sub> decreased during exercise in ET whilst RAV<sub>min</sub> was unchanged, and RAV<sub>max</sub> and RAV<sub>min</sub> were unchanged in UT. Thus, the RV and RA volume responses during exercise differed between ET and UT.</p>}},
  author       = {{Östenson, Björn and Ostenfeld, Ellen and Edlund, Jonathan and Arheden, Håkan and Steding-Ehrenborg, Katarina}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{5 May}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLOS ONE}},
  title        = {{Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0347745}},
  doi          = {{10.1371/journal.pone.0347745}},
  volume       = {{21}},
  year         = {{2026}},
}