@article{8695fc55-431d-43be-b389-ef4906264129,
  abstract     = {{<p>BACKGROUND: There are limited data guiding the optimal inflation time for coronary drug-coated balloons. The aim of this study was to assess the clinical efficacy of an inflation time of ≥30 seconds compared with &lt;30 seconds.</p><p>METHODS: We conducted an observational nationwide analysis using the SCAAR (Swedish Coronary Angiography and Angioplasty Registry) to identify all patients undergoing percutaneous coronary intervention with drug-coated balloons and their inflation times. Outcomes were assessed at 1 year using Kaplan-Meier estimates and adjusted Cox regression.</p><p>RESULTS: The &lt;30-second group comprised 412 patients, and the ≥30-second group 10 826 patients. Patients in the &lt;30-second group presented more often with lesions in proximal segments. After a 1-year follow-up, ≥30 seconds was associated with lower rates of target segment revascularization compared with &lt;30 seconds (3.2% versus 6.4%, adjusted hazard ratio [HR], 0.47 [95% CI, 0.32-0.69], P≤0.001) and target vessel myocardial infarction (1.8% versus 5.3%, adjusted HR, 0.32 [95% CI, 0.21-0.50], P≤0.001). No difference was observed for all-cause mortality.</p><p>CONCLUSIONS: In this analysis, including 11 238 patients undergoing PCI with drug-coated balloons, ≥30 second inflation time was associated with improved outcomes compared with a shorter inflation time.</p>}},
  author       = {{von Koch, Sacharias and Zhou, Mikael and Håkansson, Anton and Råmunddal, Truls and Omerovic, Elmir and Zwackman, Sammy and Erlinge, David and Rissanen, Tuomas T and Mohammad, Moman A}},
  issn         = {{2047-9980}},
  keywords     = {{Humans; Female; Time Factors; Registries; Angioplasty, Balloon, Coronary/instrumentation; Treatment Outcome; Male; Aged; Coronary Artery Disease/therapy; Coronary Angiography; Coated Materials, Biocompatible; Middle Aged; Sweden/epidemiology; Cardiac Catheters; Cardiovascular Agents/administration & dosage; Risk Factors; Percutaneous Coronary Intervention/instrumentation; Myocardial Infarction}},
  language     = {{eng}},
  month        = {{08}},
  number       = {{15}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Journal of the American Heart Association}},
  title        = {{Impact of Drug-Coated Balloon Inflation Time on Outcome After Percutaneous Coronary Intervention : An Observational Study From SCAAR}},
  url          = {{http://dx.doi.org/10.1161/JAHA.125.047354}},
  doi          = {{10.1161/JAHA.125.047354}},
  volume       = {{15}},
  year         = {{2026}},
}