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- 2020
-
Mark
Animal models for preclinical Parkinson´s research: An update and critical appraisal
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2017
-
Mark
Molecular Mechanisms of L-DOPA-Induced Dyskinesia
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l-DOPA in a rat model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Chemogenetic stimulation of striatal projection neurons modulates responses to Parkinson's disease therapy
(
- Contribution to journal › Article
- 2016
-
Mark
On the Effect of Eltoprazine in Dyskinetic Hemiparkinsonian Rats.
(
- Contribution to journal › Letter
-
Mark
Dramatic differences in susceptibility to L-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion
(
- Contribution to journal › Article
-
Mark
Signaling mechanisms in L-DOPA-induced dyskinesia
2016) p.155-188(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Validation of an improved scale for rating L-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists
(
- Contribution to journal › Article
-
Mark
Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model
(
- Contribution to journal › Article
-
Mark
Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice.
(
- Contribution to journal › Article
- 2015
-
Mark
Zooming in on the small: The plasticity of striatal dendritic spines in l-DOPA-Induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Rodent models of impulsive compulsive behaviors in Parkinson's disease: how far have we reached?
(
- Contribution to journal › Scientific review
-
Mark
Activity of serotonin 5-HT1A receptor 'biased agonists' in rat models of Parkinson's disease and l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine
(
- Contribution to journal › Article
-
Mark
NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.
(
- Contribution to journal › Article
-
Mark
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and l-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist.
(
- Contribution to journal › Article
-
Mark
Increased CSF biomarkers of angiogenesis in Parkinson disease.
(
- Contribution to journal › Article
-
Mark
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.
(
- Contribution to journal › Article
-
Mark
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.
(
- Contribution to journal › Scientific review
- 2014
-
Mark
Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications.
(
- Contribution to journal › Scientific review
-
Mark
Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Chapter 22 - Rodent Models of Treatment-Related Complications in Parkinson Disease
2014) p.373-386(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.
(
- Contribution to journal › Article
-
Mark
Mechanisms of Dopamine D1 Receptor-Mediated ERK1/2 Activation in the Parkinsonian Striatum and Their Modulation by Metabotropic Glutamate Receptor Type 5.
2014) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 34(13). p.4728-4740(
- Contribution to journal › Article
-
Mark
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
- 2013
-
Mark
Bad News for Neuroprotective Therapies in PD?
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: Effects of combined treatment and possible mechanisms of action.
(
- Contribution to journal › Article
-
Mark
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism.
(
- Contribution to journal › Article
- 2012
-
Mark
Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to l-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels
(
- Contribution to journal › Article
-
Mark
A Model of GDNF Gene Therapy in Mice with 6-Hydroxydopamine Lesions: Time Course of Neurorestorative Effects and ERK1/2 Activation
(
- Contribution to journal › Article
-
Mark
Levodopa-induced dyskinesia is strongly associated with resonant cortical oscillations.
2012) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 32(47). p.16541-16551(
- Contribution to journal › Article
-
Mark
Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
- 2011
-
Mark
Parkinson disease: Poor results for retinal cell transplants in Parkinson disease.
(
- Contribution to journal › Article
-
Mark
Current Options and Future Possibilities for the Treatment of Dyskinesia and Motor Fluctuations in Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
The locus coeruleus Is Directly Implicated in L-DOPA-Induced Dyskinesia in Parkinsonian Rats: An Electrophysiological and Behavioural Study
(
- Contribution to journal › Article
-
Mark
In vivo microdialysis studies of striatal dopamine efflux and its relationship to L-DOPA-induced dyskinesia in mouse models of Parkinson's disease.
2011) 41st Annual Meeting of the Society-for-Neuroscience(
- Contribution to conference › Abstract
-
Mark
Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Cortical resonance around 80 Hz is linked to dyskinesia after levodopa treatment in a rodent model of Parkinson’s disease
2011) Annual Meeting of Society for Neuroscience 2011(Neuroscience 2011)(
- Contribution to conference › Abstract
-
Mark
Mechanisms underlying cortical resonance in levodopa-induced dyskinesia
2011) Annual Meeting of Society for Neuroscience 2011(Neuroscience 2011)(
- Contribution to conference › Abstract
-
Mark
Putaminal Upregulation of FosB/Delta FosB-Like Immunoreactivity in Parkinson's Disease Patients with Dyskinesia
(
- Contribution to journal › Article
-
Mark
Apoptosis-inducing factor mediates dopaminergic cell death in response to lps-induced inflammatory stimulus Evidence in Parkinson's disease patients.
(
- Contribution to journal › Article
-
Mark
Vascular endothelial growth factor is upregulated by L-dopa in the parkinsonian brain: implications for the development of dyskinesia.
(
- Contribution to journal › Article
- 2010
-
Mark
Post- Versus Pre-Synaptic Plasticity
(
- Contribution to journal › Published meeting abstract
-
Mark
6-OH Dopamine Rat Model
2010) p.3-5(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Climbing behaviour
2010) p.26-27(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Tail-pinch stimulus
2010) p.209-210(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Recent Advances In Parkinson'S Disease: Translational And Clinical Research Preface
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Maladaptive striatal plasticity in L-DOPA-induced dyskinesia.
(
- Contribution to journal › Scientific review
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Recent advances in Parkinson's disease : basic research. Preface
(
- Contribution to journal › Article
-
Mark
Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Immunohistochemical Detection of Fosb/Delta fosb-Like Proteins Maps Areas of Maladaptive Neuroplasticity in the Post-Mortem Parkinsonian Brain
(
- Contribution to journal › Published meeting abstract
-
Mark
Differential molecular and behavioural response to L-DOPA in mice injected with 6-hydroxydopamine in the striatum or in the medial forebrain bundle
2010)(
- Contribution to conference › Poster
-
Mark
L-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia.
(
- Contribution to journal › Article
-
Mark
Deuterium substitutions in the L-DOPA molecule improve its anti-akinetic potency without increasing dyskinesias
(
- Contribution to journal › Article
-
Mark
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys.
(
- Contribution to journal › Article
-
Mark
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.
(
- Contribution to journal › Article
- 2009
-
Mark
Pathophysiology of L-DOPA-Induced Dyskinesia in Parkinson's Disease
2009) p.434-444(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Dopamine replacement therapy in Parkinson´s Disease: past, present and future
2009) p.309-334(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Rodent models of treatment-induced motor complications in Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Plastic effects of L-DOPA treatment in the basal ganglia and their relevance to the development of dyskinesia.
(
- Contribution to journal › Article
-
Mark
Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats.
(
- Contribution to journal › Article
-
Mark
Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signalling.
(
- Contribution to journal › Article
-
Mark
Chronic intermittent L-DOPA treatment induces changes in dopamine release
(
- Contribution to journal › Article
- 2008
-
Mark
Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Two routes for L-dopa to be converted to dopamine
2008) 15th Annual Meeting of the American Society for Neural Therapy and Repair In Cell Transplantation 17(4). p.482-482(
- Contribution to journal › Published meeting abstract
-
Mark
l-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation
(
- Contribution to journal › Article
- 2007
-
Mark
L-DOPA-induced dyskinesia: cellular mechanisms and approaches to treatment.
(
- Contribution to journal › Article
-
Mark
Dopamine dysregulation of movement control in l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Advances in understanding l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice.
2007) In Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] Chapter 9(Oct). p.9-25(
- Contribution to journal › Article
-
Mark
Modulation of l-DOPA-induced abnormal involuntary movements by clinically tested compounds: Further validation of the rat dyskinesia model.
(
- Contribution to journal › Scientific review
-
Mark
Expression pattern of JunD after acute or chronic l-DOPA treatment: Comparison with DeltaFosB.
(
- Contribution to journal › Article
-
Mark
The "motor complication syndrome" in rats with 6-OHDA lesions treated chronically with l-DOPA: Relation to dose and route of administration.
(
- Contribution to journal › Article
-
Mark
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors
(
- Contribution to journal › Article
-
Mark
Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
High dose levodopa therapy is not toxic in multiple system atrophy: Experimental evidence
(
- Contribution to journal › Article
-
Mark
Proteomic analysis of striatal proteins in the rat model of l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
- 2006
-
Mark
Mechanisms of L-DOPA-induced dyskinesia in Parkinson´s disease: What do animal models tell us?
2006) p.351-360(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Post- versus presynaptic plasticity in L-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Dyskinesia and neural grafting in Parkinson's disease
2006) p.184-224(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease.
(
- Contribution to journal › Letter
-
Mark
The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.
(
- Contribution to journal › Article
-
Mark
Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Role of striatal l-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats.
(
- Contribution to journal › Article
-
Mark
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.
(
- Contribution to journal › Article
- 2005
-
Mark
Dyskinesias and dopamine cell replacement in Parkinson's disease: a clinical perspective.
(
- Contribution to journal › Article
-
Mark
Chapte B7 - Utility of 6-hydroxydopamine lesioned rats in the preclinical screening of novel treatments for Parkinson disease
2005) p.193-208(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors.
(
- Contribution to journal › Article
- 2004
-
Mark
A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function.
(
- Contribution to journal › Article
-
Mark
Effects of pulsatile L-DOPA treatment in the double lesion rat model of striatonigral degeneration (multiple system atrophy)
(
- Contribution to journal › Article
-
Mark
Transcriptome analysis in a rat model of L-DOPA-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism
(
- Contribution to journal › Article
- 2003
-
Mark
Cellular and behavioural effects of the adenosine A2a receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article